Analogues of nemosol, their comparison and reviews. Action of suppositories makmiror in case of damage to the genitourinary system makmiror complex of suppositories from inflammation


Macmiror cream is a medicinal drug used to treat a number of infections of the genitourinary system of bacterial and fungal origin. It is a very effective and completely safe medicine designed to cure inflammation of the genital organs in women caused by these infections, but also to prevent candidiasis, a disease that can appear in response to the use of other drugs.

Macmiror cream and its action

Macmiror cream is an antibacterial medication with a rather wide spectrum of action. His active substance - Nifuratel, a derivative of nitrofuran, has a detrimental effect on many pathogenic microorganisms: bacteria, protists and fungi. It shows high efficiency and at the same time has low toxicity.

Macmiror cream is primarily intended for the treatment of vulvovaginitis - inflammation of the vagina and external genital organs in women.

Various infectious agents can cause this disease:

  • staphylococci;
  • trichomonas;
  • chlamydia;
  • escherichia coli;
  • fungi, etc.

The therapeutic effect of Macmiror cream in the treatment of vulvovaginitis is based on the fact that most pathogens of this disease of a bacterial and fungal nature also exhibit increased sensitivity to nifuratel. The drug is excreted from the body along with urine, continuing to provide a therapeutic effect in the urinary tract, destroying microorganisms that cause pyelonephritis, cystitis, urethritis and pyelitis.

Macmiror complex and its action

If several pathogens simultaneously become the cause of infectious lesions of the female genital organs, then you can get rid of them with the help of McMiror ointment complex. In addition to nifuratel, this drug also contains nystatin, a substance with an antimycotic effect used in the treatment of fungal diseases, in particular candidiasis.

Macmiror complex cream is a combined drug that is intended for topical use for gynecological problems, primarily vulvovaginitis. A more pronounced therapeutic effect from it is explained by the powerful effect of 2 medicinal substances at once that are part of it.

Nifuratel perfectly kills various bacteria:

  • hay and colibacillus;
  • shigella;
  • salmonella;
  • pathogenic enterococci;
  • klebsiella;
  • staphylococci;
  • Helicobacter pylori (even strains resistant to metronidazole),

as well as protozoa (Trichomonas, lamblia and amoeba), fungi of the genus Candida. The second substance, nystatin, acts only on pathogenic fungi, especially on the aforementioned yeast-like Candida and Aspergillus fungi, but it is inactive against bacteria. The substance has poor absorption, its main part is excreted from the body of patients in the feces.

How to use McMiror cream

When treating vaginal diseases, Macmiror cream should be used for at least 7 or 8 days.

It is very convenient to use the cream, for this you need:

  1. Take a tube of cream that contains 30 g of medicinal contents.
  2. Remove the cap and put on the special applicator that comes with the product in its place.
  3. Press down on the tube and draw up the required dose of cream using the scale on the applicator (in grams). For a single use, it is enough to take 2.5 g of ointment.
  4. After that, remove the applicator from the tube, carefully insert it deeply into the vagina and squeeze the medicinal contents inside it.

Macmiror cream is suitable for both curing and preventing infections that affect the external genital organs in women. To do this, apply a single dose of the cream to their mucous membranes and leave until the next treatment. The medicinal cream should be used 1 or 2 times throughout the day, preferably in the morning or evening. On the days when therapy takes place, it is necessary to completely abandon sexual intercourse. At this time, it is advisable to treat your sexual partner as well.

Unlike many antibiotic medications, Ointment McMiror and McMiror complex do not violate the composition of the natural vaginal microflora and therefore it is quite possible to use them in case of vaginal dysbiosis or during the restoration of its normal microflora. In addition, Macmiror is able not only to suppress the growth of pathogenic microorganisms, but also promotes the multiplication of bifidobacteria and lactobacilli, normalizing the composition of the vaginal microflora and its acid-base balance.


For this reason, after the application of Macmirora, there is no need to use drugs to restore the lost natural vaginal environment. The cure of the diseases against which McMiror is directed is quick and painless, the period of therapy is significantly reduced, and the risk of contracting a secondary infection is reduced to a minimum.

Contraindications and side effects of the drug

Instructions for use indicate that Macmiror cannot be used by women with individual intolerance to its active ingredients: nifuratel or nystatin. During pregnancy, especially in the 1st trimester, and during the period of breastfeeding, women are prescribed it in rare cases. This is done only when the therapeutic effect of the drug presumably exceeds the harm that the active substance of Macmiror cream can cause to a developing fetus or infant (nifuratel is able to penetrate the hemoplacental barrier, as well as into breast milk).

Among adverse reactions, which complicates the intake of McMiror cream, skin rash and itching are noted, but they appear quite rarely, as well as cases of drug overdose. But, despite the fact that McMiror is easy to use and relatively safe, you cannot prescribe it yourself. Only a physician with the necessary knowledge can correctly prescribe this medication.


yachist.ru

pharmachologic effect

Macmiror complex is indicated for topical use, has an antibacterial, antifungal, antiprotozoal effect (affects protozoa - toxoplasma, trypanosomes, pneumocysts, lamblia, amoeba, Trichomonas, leishmania).

The active substances of the complex are nifuratel (a nitrofuran derivative), which is active against fungi, protozoa, bacteria, and nystatin is an antibiotic with an antifungal effect, especially effective against Candida albicans.

The combination of nystatin and nifuratel allows to achieve a significant antifungal effect, expand the spectrum of antimicrobial action.

Judging by the McMiror reviews, the complex does not provoke dysbiosis, it quickly restores the normal vaginal flora.

Release form

Produce vaginal cream, McMiror complex suppositories.

Indications for use

According to the McMiror instructions, the complex is prescribed for the treatment of vaginal infections provoked by microorganisms sensitive to the drug: vaginal candidiasis, urogenital trichomoniasis, bacterial infections developing in the urogenital region.

Instructions for the use of McMirora

Suppositories Makmiror complex is used for treatment for 8 days. - one candle is injected every day.

The duration of treatment can be adjusted by the attending physician. To improve efficiency, the candle is inserted into the upper vagina.

Macmiror complex cream is injected using a special applicator one or two p / day in an amount of 2.5 g - in the evening or in the morning (to use the cream, the applicator is wound onto a tube, the cream is squeezed into it, focusing on the scale applied to it). The applicator is disconnected from the tube, inserted into the vagina, and then, pressing on the rod, the cream is squeezed inside. Therapy also lasts on average 8 days. Only a doctor can adjust the cream treatment regimen. The special design of the applicator allows you to inject the cream without the risk of damaging the hymen. To do this, before the introduction of Macmiror complex cream, it is necessary to remove the cannula from the rod and put it on the syringe from the opposite side.

Side effects

Contraindications to the use of Makmirora

According to the McMiror instructions, the complex is contraindicated in case of individual intolerance.

During pregnancy, lactation, it is not recommended to use the complex - only in special cases and with caution.

www.neboleem.net

Clinical and pharmacological group

A drug with antibacterial, antiprotozoal and antifungal effects for local use in gynecology.

Terms of dispensing from pharmacies

Dispensed by prescription.

Prices

How much does McMire cost? The average price in pharmacies is 750 rubles.

Release form and composition

"Macmiror complex" candles consist of:

  • Nifuratela (500 mg in one suppository)
  • Nystatin
  • Excipients.

"Makmiror complex" candles are available in blisters of two options:

  • 8 suppositories in one
  • 12 suppositories in one.

A cardboard package contains 1 blister. The candles are oval, yellow-brown in color. In the middle of the suppository there is an oily liquid with a yellow tint. The suppository itself is soft to the touch (gelatinous consistency).

Pharmacological effect

Macmiror complex is a combined medication for local use in the treatment of gynecological diseases. The pharmacological properties of the drug are due to the action of its active ingredients. The main active ingredients of the drug are nystatin and nifuratel.

Nystatin is a mycostatic antimicrobial agent, the action of which is aimed at destroying fungal cells (by attaching to sterols in the membrane of fungal cells, it disrupts their structure, while destroying the cell itself). Nystatin is highly active against Candida fungi. When combined with nifuratel, a powerful, pronounced antimycotic effect is provided.

The drug has antifungal, antibacterial and antiprotozoal effect (it is active against protozoa - trypanosomes, toxoplasma, pneumocysts, amoeba, lamblia, trichomonads). Due to such a variety of effects, this drug is used in the treatment of a wide variety of vaginal infections.

Indications for use

Macmiror complex is prescribed for the treatment of vaginal infections provoked by microorganisms sensitive to the drug: vaginal candidiasis, urogenital trichomoniasis, bacterial infections developing in the urogenital area.

Good reviews about the Macmiror complex used in the local treatment of chlamydial infections.

Contraindications

The drug can only be used as directed by a doctor. Before starting the use of suppositories, patients should carefully read the attached instructions. The main contraindication is the individual intolerance of the components included in the preparation.

Relative contraindications for use are pregnancy in the 1st trimester and age up to 18 years due to lack of experience with adolescents.

Use during pregnancy and lactation

For pregnant women, this antibiotic can only be prescribed by a doctor on strict indications. This takes into account the potential risk to the fetus, because the main component of nifuratel is able to penetrate the placenta.

If it becomes necessary to use the drug during lactation, then at the time of taking the woman should suspend feeding (the main active ingredient enters breast milk).

Dosage and method of administration

The instructions for use indicate that to achieve the maximum effect, the suppository is inserted deep into the vagina.

  • Intravaginally: 1 vaginal suppository is administered daily in the evening before bedtime for 8 days or as recommended by a doctor.

During menstruation, the use of suppositories is not recommended, since the therapeutic effect will be significantly reduced. If a woman knows that her menstruation should begin one of these days, then it is better to postpone the course of treatment until the end of the critical days.

Side effects

The Macmiror complex is usually well tolerated, only in rare cases there are allergic manifestations in the form of a rash, itching on the skin.

Overdose

Since the absorption of the drug McMiror Complex is very low and the drug acts locally, the probability of an overdose is negligible. The uncontrolled use of suppositories is not recommended, since the above-described side effects may occur against this background.

special instructions

It is necessary to carry out simultaneous treatment of the sexual partner due to the danger of re-infection. During the period of drug treatment, sexual intercourse should be avoided.

Suppositories are not used for treatment in childhood, if it is necessary to use the drug in this category of patients, it is recommended to use the drug Macmiror Complex in dosage form vaginal cream complete with an applicator (graduated syringe). The presence of a special nozzle allows you to inject the cream without damaging the hymen.

Drug interactions

Clinically significant interaction of Macmiror Complex cream with other drugs has not been established.

Nemozole or Vormil

Patients and doctors are always looking for a drug that better and faster affects the causative agent of the disease. It is very difficult to answer the question of which anthelmintic agent is better - Nemozol or Vormil, since these drugs have one active ingredient (albendazole). The same active ingredient means that both drugs have the same side effects and contraindications.

Sometimes there are cases when it becomes necessary to replace a drug with a drug that will act in a similar way.

To date, the following drugs are provided on the pharmacological market, which are substitutes for Nemozole:

  1. 1 Gelmodol-VM.
  2. 2Sanoxal.
  3. 3 Albendazole.

The above medications have the same active substance in their composition as Nemozol.

A similar spectrum of effects on the body, treatment of similar diseases and elimination of symptoms can be achieved using the following drugs:

  1. 1 Mebendazole.
  2. 2 Vermox.
  3. 3 Medamin.

Medamin is a drug that has a pronounced anthelmintic effect. As a result of taking the medicine by the patient in the helminths that live in the intestines, the mechanism of blocking the nervous system is activated and their further death occurs.

How to take medications

What pharmacological properties does the drug have?

The drug Nemozol, in terms of its pharmacological effect, is widely used as an anthelmintic agent. Today it is one of the most effective pharmacological drugs, which has a wide range of effects on the human body.

Various pharmaceutical manufacturing companies can produce this medicine in different forms:

  1. 1 Tablet form, which is presented on the market in different dosages (200 or 400 mg of the main active ingredient). Available in one or two tablets in a package (blister).
  2. 2Suspension. Sold in 20 ml plastic bottles. 5 ml of suspension accounts for 100 mg of the main component.
  3. 3 In the form of chewable tablets. This pharmacological form has a dosage of 400 mg of albendazole.
  4. 4 Creamy form for external use.
  • enterobiasis;
  • ascariasis;
  • trichinosis;
  • syndrome skin, which is often referred to as "migratory larva";
  • giardiasis, which often manifests itself in childhood.

Features of the use of antihelminthic drugs

Most drugs designed to get rid of helminthic invasion have a quick therapeutic effect.

When treating an ailment with low-toxic drugs, it is important to follow the individual dosage regimen recommended by the doctor and monitor the body's response. In some cases, side effects may develop: dizziness, skin rashes and itching, leukopenia, pancytopenia

As well as the original Indian drug, and analogs of "Nemozol" can affect blood pressure, cause an increase in body temperature, impair kidney function. Synthetic drugs, despite the minimum content of toxic substances in the composition, have a negative effect on the liver, immune system and blood cells.

Which analogs are better

Vermox is based on mebendazole. Nemozole and Vermox are used at the same frequency. One of the nuances noted by the attending physicians is the constant adherence to enhanced contraception. Vormil cannot be compared with Nemosol. The presented drugs are generic albendazole. They have not only an identical clinical effect, but also a component composition.

How to use the drug

The drug is allowed to be taken from the age of two. Thus, the average dosage of the drug for children (over two years old) and adults is 400 mg (one or two tablets, depending on the dose) or 20 ml of suspension. It should be remembered that only a medical professional can determine the exact dosage. The drug is taken once. It should be borne in mind that the doctor may prescribe a drug little child under two years old, but then the single dosage will be reduced to 200 mg. Moreover, for such a category of patients, a medicine in the form of a suspension is used.

To achieve the maximum effect, the instructions for use recommend using the medicine during meals.

The duration of taking the drug in the treatment of various diseases and lesions may differ:

  1. 1 The drug should be taken within three days if stongyloidosis or teniasis is present.
  2. 2 The symptoms of toxocariasis will be eliminated with ten days of therapy. In this case, a single dosage is determined by a doctor. The number of receptions per day is one time.
  3. 3 Neurocysticercosis and echinococcosis are treated using the dosage of the drug based on the patient's body weight. The attending physician calculates the dosage of the drug for each patient individually, taking into account the patient's weight and the characteristics of his body. The duration of therapeutic treatment is 28 days. After a two-week break, the course of taking the medication should be repeated.
  4. 4 In order to avoid the development of neurocysticercosis in the patient's body, the drug should be used for therapeutic purposes for seven days to a month.

It should be remembered that the dosage and duration of therapy is prescribed by the attending physician.

Analogues of Nemozol

Analogues of Nemozol

Only the attending physician can unambiguously decide which drug is better, he also replaces the drug if necessary.

Nemozole and analogues

The main active ingredient of Nemozole is albendazole, a methyl ester of carbamic acid. There are only a few registered analogues of Nemozol: Gelmodol VM, Vormil and Sanoxal with the same active substance.

Contraindications to the use of Nemozol and its analogs - Gelmodol VM, Vormil and Sanoxal are allergies to the components of the product, the period of gestation and breastfeeding, as well as to children under 6 years of age (studies on the toxic effect of drugs on the body of preschoolers have not been carried out, therefore it is better choose other medicines).

The drug is used with caution in patients with insufficient bone marrow function, liver cirrhosis, liver failure, as well as in case of retinal lesions in cysticercosis. When prescribing medicines based on Nemozole, the attending physician assesses all the risks and feasibility of treatment, and also monitors the patient's condition at the time of therapy

Nemozole for children

How to take Nemozole correctly? In the course of treatment, there is no need for additional use of laxatives. The drug Nemozole for children is prescribed by mouth, the drug should be drunk before meals or half an hour after meals. You don't need to follow any diet either. To prevent recurrence of the disease after undergoing a course of treatment, prophylactic intake of Nemozole with the whole family is desirable.

Features of the appointment of Nemozole for children under 2 years of age:

  • Tablets for worms Nemozol for diseases such as cestodosis and stongyloidosis should be taken at 200 mg. The treatment period is three days. The therapy should be repeated after a couple of weeks.
  • With more harmless helminthiasis - enterobiasis or ascariasis, a single use of the Nemozol tablet is enough.

How to take Nemozole for children correctly? The dosage for babies is calculated as follows: per 1 kg of the baby's weight, 15 mg drug per day. The duration of treatment is a week.

Woman - this is a gentle and fragile creature. Her body, her health, too, cannot be distinguished by heroic indicators. Therefore, diseases associated with infectious infections of her genitals are not something unusual and rare.

It is quite difficult to do without antibiotics these days. They do an excellent job with all kinds of microbial and bacterial ailments, but at the same time they can cause unprecedented harm to the female body, causing a relapse of some "sleeping" sluggish disease and other unpleasant moments. There is more than one remedy to resist this and help a woman. McMiror candles have proven themselves quite well in this regard. They not only effectively, but also gently affect the body of women and are one of the most popular assistants in the most unpredictable and unpleasant cases.

Description

Many gynecological diseases are treated with antimicrobial medicines broad action. It is to them that the McMiror complex belongs. Due to the fact that nystatin and nifuratel, which are the main components of these suppositories, are not very toxic, their effect on the body is not too noticeable and with minimal side effects. Moreover, the body does not get used to nifuratel, which means that in the event of a repeated illness, it is quite possible to be treated again with McMiror vaginal suppositories.

The great advantage of this drug over all the others is that it does not cause vaginal dysbiosis and gently affects its microflora.

The fact that this tool combines nystatin with nifuratel further expands the spectrum of its action. Nystatin has always been one of the strongest agents for fighting fungi, and nifurathrel is an excellent antimicrobial, antibacterial and antifungal medicine.

Getting into the body of women, the active components of Macmiror, a complex of suppositories, instantly protect it from the penetration of harmful microorganisms and simultaneously kill them.

Macmiror is afraid of such microorganisms:

  • amoeba;
  • toxoplasma;
  • lamblia;
  • trichomonas;
  • trypanosoma, etc.

The pharmacokinetics of a drug can be tracked with great difficulty because it is absorbed in the body for a long time.

Many doctors and patients are almost unanimously positive about the McMirore vaginal complex. Such reviews allow us to draw conclusions about their high efficiency.


Women who have used these candles say with complete confidence that they can easily help to overcome many female ailments. Suppositories McMiror are prescribed for:

  1. thrush;
  2. female urethritis;
  3. bacterial vaginosis;
  4. vaginal trichomoniasis and many other, purely female problems.

In just a couple of days, all signs of diseases and unpleasant symptoms associated with them disappear, helping to completely eliminate all the negative effects of antibiotics on the body of women.

The cons of the candles are insignificant. Many point to their bright color, which can stain underwear. But this problem can be easily solved if you use panty liners when treating with McMiror candles. Many women are not happy with their rather high price. But they are really effective and can get rid of several diseases at the same time. In addition, they are an excellent prophylactic agent that prevents secondary infection with an infectious and fungal disease.

Instructions for use


McMiror suppositories are used vaginally. In order to achieve the desired therapeutic effect, one suppository per day will be sufficient.

It is advisable to insert the suppository deep into the vagina right before bedtime to avoid the medicine from leaking out of the vagina when the woman walks.

Before you enter the candle, you need to wash your hands and genitals well. Yet more effective treatment it will be if, before the introduction of the candle, you do douching with chamomile or calendula, but in no case should you use soap solutions.

Women with long manicure should be extremely careful when inserting a candle into the vagina to avoid possible injury to the mucous membrane and re-infection.

"Macmiror complex 8" is called so because, according to official recommendations, it takes 8 days to use these candles for full recovery. Only in some cases, a venereologist or gynecologist can extend the treatment with suppositories up to 10-14 days.

It is inappropriate to use suppositories during menstruation. It is advisable to calculate and undergo a course of treatment before her.

There are cases when a woman has been treated, but the therapeutic effect has not been achieved. In such cases, you should wait for menstruation, and after them continue treatment.

The use of these suppositories for the treatment of children is not applicable. If necessary, apply this tool only in the form of a cream.

Application during pregnancy and lactation


As already mentioned, the components of McMiror suppositories are very slowly absorbed in a woman's body and practically does not penetrate into her blood. Therefore, it can be used in the treatment of pregnant women who are often haunted by thrush. But still, with caution, you need to use candles for pregnant women in the first trimester, when it is better to refrain from any medications. Teratogenic and toxic effects on the unborn baby during the treatment of pregnant women with this medication were not identified.

Also, the components of McMiror suppositories do not enter breast milk and are not excreted with it, therefore they are allowed to be used by nursing mothers, but also with great care and under the constant supervision of the attending physician.

Side effects


Macmiror vaginal suppositories in complex treatment are normally tolerated by women of all ages. Of 100%, only 6.5% were noticed negative consequences of the use of candles.

In some cases, women develop:

  • rash;
  • red spots;
  • hyperemia of the vaginal mucosa;
  • discharge of unknown origin.

If a woman develops one or more of these pronounced symptoms, you should immediately inform the attending physician about it, who will rule out a severe form of allergy and consider further treatment with this remedy. Side effects disappear almost immediately after stopping the use of this drug. Antihistamines are sometimes prescribed.

Overdose


Using these suspensions for local administration, overdose has not been observed in any case to date. Their interaction with other medications did not bring either positive or negative results in the study.

More about McMiror candles


It should be remembered that when treating with this drug, one should completely abstain from alcohol and sexual activity. And it doesn't matter at all what kind of disease a woman is being treated for. From neglected chlamydia or from a banal, at first glance, harmless thrush. It is advisable to undergo treatment for two partners. For a man, a cream with the same constituent components is suitable. The same cream will help virgins in the fight against female infectious diseases. The cream is equipped with a special graduated applicator that will help the girl inject the medicine without harming her hymen.

No interaction with other medications was noticed.


In order for the constituent suppositories to be evenly distributed in the vagina, it must be inserted as deeply as possible.

Nystatin and nifuratel do not enter the blood plasma and do not accumulate in the organs and tissues of women.

You can be treated with McMiror candles and drive a car, as well as engage in other activities that require concentration of attention.

Contraindications


As mentioned above, McMiror candles act quite mildly on female organs. There are almost no contraindications for this drug. Except only for the individual intolerance of a woman to its components.

Storage conditions and periods


McMiror candles are stored in a dry, dark and cool place at a temperature not exceeding 26 degrees, away from children. If candles are stored in the refrigerator, they should not be allowed to freeze in the cream.

  • glycerol , sodium methyl parahydroxybenzoate, propylene glycol, triethanolamine 30%, xalifin, sodium propyl parahydroxybenzoate, 70% sorbitol solution, water.
  • The composition of vaginal suppositories includes:

    • nystatin, nifuratel ;
    • glycerin, titanium dioxide, sodium ethyl parahydroxybenzoate, gelatin, yellow iron oxide.

    Release form

    Vaginal suppositories are produced in cartons containing a blister, in which there are 8 or 12 suppositories.

    Vaginal cream is produced in an aluminum tube containing 30 g of cream. The kit also includes an applicator (graduated syringe).

    pharmachologic effect

    The tool has antibacterial, antifungal and antiprotozoal effects.

    Pharmacodynamics and pharmacokinetics

    Macmiror Complex is a combined antifungal drug local action. Nifuratel effectively fights against many types of bacteria, fungi and protozoan microorganisms (for example, Trichomonas vaginalis ).

    Nystatin is an antifungal antibiotic. Violates the permeability of the membrane of fungi, after which the cell is destroyed. Particularly effective against fungi Candida albicans .

    The combination of nystatin and nifuratel makes it possible to increase the effectiveness of antifungal action and expand the range of indications for use.

    Makmikor Complex has low toxicity, due to which it does not destroy the physiological flora, does not cause dysbacteriosis and quickly restores the normocenosis of the vagina.

    Indications for use

    Comprehensive treatment vulvovaginal infections which are caused by bacteria, Candida fungi, chlamydia and Trichomonas.

    Contraindications

    Sensitivity to any component of the drug.

    Side effects

    Allergic reactions were extremely rare - and skin rash .

    Instructions for the use of candles and cream Makmiror Complex (Method and dosage)

    The drug is used ingravaginally .

    Every day for 8 days before going to bed, 2.5 g of cream is applied using the applicator. The instruction for suppositories Macromir Complex is the same as for the ointment, 1 suppository should be administered per day. To maximize the effect, the suppository is inserted into the upper part of the vagina. After menstruation, you can repeat the treatment if necessary.

    In childhood, vaginal suppositories are not used, in such cases it is recommended to use cream with applicator .

    Overdose

    No cases of drug overdose have been recorded.

    Interaction

    The significant effect of the drug with other drugs has not been established.

    Storage conditions

    The drug should be stored at a temperature not exceeding 25 ° C, in a dark place.

    Terms of sale

    The drug is sold by prescription in pharmacies.

    Shelf life

    special instructions

    At the same time, the sexual partner should be treated using a cream for men to avoid the risk of re-infection. You should refrain from sexual intercourse during the course of treatment.

    Long-term use of the drug can cause hypersensitivity reactions.

    Stop using the drug if allergic reaction .

    Analogs

    Analogues of candles Makmiror Complex:, , Povidin .

    During pregnancy and lactation

    Reviews for McMiror Complex

    Reviews about McMiror Complex candles and about the cream are positive, all patients note the ease of use, the absence of odor, the effectiveness and speed of action of the product. Among the disadvantages are the unpleasant yellow color of the suppositories and the cost.

    You can also find reviews on the McMiror Complex during pregnancy, despite the fact that it is not recommended to use it in this case.

    Price for Macmiror Complex

    Cream in Russia costs 465 rubles, in Ukraine - 172 UAH.

    The price of McMiror Complex candles in Russia averages 491 rubles, in Ukraine - 109 UAH.

    • Online pharmacies in RussiaRussia
    • Online pharmacies of UkraineUkraine

    Macmiror complex is indicated for topical use in gynecology.

    It has antibacterial, antifungal, antiprotozoal effect (affects protozoa - toxoplasma, trypanosomes, pneumocysts, lamblia, amoeba, Trichomonas, leishmania).

    The active substances of the complex are nifuratel (a nitrofuran derivative), which is active against fungi, protozoa, bacteria, and nystatin is an antibiotic with an antifungal effect, especially effective against Candida albicans.

    Clinical and pharmacological group

    A drug with antibacterial, antiprotozoal and antifungal effects for local use in gynecology.

    Terms of dispensing from pharmacies

    Dispensed by prescription.

    Prices

    How much does McMire cost? The average price in pharmacies is 750 rubles.

    Release form and composition

    "Macmiror complex" candles consist of:

    • Nifuratela (500 mg in one suppository)
    • Nystatin
    • Excipients.

    "Makmiror complex" candles are available in blisters of two options:

    • 8 suppositories in one
    • 12 suppositories in one.

    A cardboard package contains 1 blister. The candles are oval, yellow-brown in color. In the middle of the suppository there is an oily liquid with a yellow tint. The suppository itself is soft to the touch (gelatinous consistency).

    Pharmacological effect

    Macmiror complex is a combined medication for local use in the treatment of gynecological diseases. The pharmacological properties of the drug are due to the action of its active ingredients. The main active ingredients of the drug are nystatin and nifuratel.

    Nystatin is a mycostatic antimicrobial agent, the action of which is aimed at destroying fungal cells (by attaching to sterols in the membrane of fungal cells, it disrupts their structure, while destroying the cell itself). Nystatin is highly active against Candida fungi. When combined with nifuratel, a powerful, pronounced antimycotic effect is provided.

    The drug has antifungal, antibacterial and antiprotozoal effect (it is active against protozoa - trypanosomes, toxoplasma, pneumocysts, amoeba, lamblia, trichomonads). Due to such a variety of effects, this drug is used in the treatment of a wide variety of vaginal infections.

    Indications for use

    Macmiror complex is prescribed for the treatment of vaginal infections provoked by microorganisms sensitive to the drug: bacterial infections developing in the urogenital region.

    Good reviews about the McMiror complex used locally.

    Contraindications

    The drug can only be used as directed by a doctor. Before starting the use of suppositories, patients should carefully read the attached instructions. The main contraindication is the individual intolerance of the components included in the preparation.

    Relative contraindications for use are pregnancy in the 1st trimester and age up to 18 years due to lack of experience with adolescents.

    Use during pregnancy and lactation

    For pregnant women, this antibiotic can only be prescribed by a doctor on strict indications. This takes into account the potential risk to the fetus, because the main component of nifuratel is able to penetrate the placenta.

    If it becomes necessary to use the drug during lactation, then at the time of taking the woman should suspend feeding (the main active ingredient enters breast milk).

    Dosage and method of administration

    The instructions for use indicate that to achieve the maximum effect, the suppository is inserted deep into the vagina.

    • Intravaginally: 1 vaginal suppository is administered daily in the evening before bedtime for 8 days or as recommended by a doctor.

    During menstruation, the use of suppositories is not recommended, since the therapeutic effect will be significantly reduced. If a woman knows that her menstruation should begin one of these days, then it is better to postpone the course of treatment until the end of the critical days.

    Side effects

    The Macmiror complex is usually well tolerated, only in rare cases there are allergic manifestations in the form of a rash, itching on the skin.

    Overdose

    Since the absorption of the drug McMiror Complex is very low and the drug acts locally, the probability of an overdose is negligible. The uncontrolled use of suppositories is not recommended, since the above-described side effects may occur against this background.

    special instructions

    It is necessary to carry out simultaneous treatment of the sexual partner due to the danger of re-infection. During the period of drug treatment, sexual intercourse should be avoided.

    Suppositories are not used for treatment in childhood, if it is necessary to use the drug in this category of patients, it is recommended to use the drug Macmiror Complex in a vaginal cream dosage form complete with an applicator (graduated syringe). The presence of a special nozzle allows you to inject the cream without damaging the hymen.

    Drug interactions

    Clinically significant interaction of Macmiror Complex cream with other drugs has not been established.