ATX codes for SODIUM ALGINAT

A02AX (Antacids in combination with other drugs)
B02BC (Hemostatic preparations for local use)

Analogues of the drug SODIUM ALGINAT by ATH codes:

Before using the drug SODIUM ALGINAT, you should consult your doctor. This instruction manual is intended solely for information. For more information, please refer to the manufacturer's annotations.

SODIUM ALGINAT: Clinico-pharmacological groups

27.024 (The drug with hemostatic, anti-inflammatory and wound-healing effect for local use in proctology)
11.008 (Antacid preparation)

SODIUM ALGINAT: Pharmacological action

Hemostatic preparation for local use. It is a natural polysaccharide derived from brown algae. It has a pronounced hemostatic effect, has anti-inflammatory and reparative properties.

SODIUM ALGINAT: Dosage

Apply rectally 2 times / day. The duration of treatment is 7-14 days depending on the severity of the disease.

SODIUM ALGINAT: Pregnancy and lactation

Perhaps rectal use during pregnancy and lactation according to indications.

SODIUM ALGINAT: Side Effects

Possible: allergic reactions.

SODIUM ALGINAT: Indications

Anal fissures in the epithelialization stage, chronic bleeding hemorrhoids, proctosigmoiditis, inflammation of the rectum in the postoperative period.

SODIUM ALGINAT: Contraindications

Hypersensitivity to sodium alginate.

Russian name

Sodium Alginate

Latin substance name Sodium Alginate

Natrii alginas ( kind of  Natrii alginatis)

Pharmacological group of substance Sodium alginate

Nosological classification (ICD-10)

CAS code

9005-38-3

Characteristics of the substance Sodium alginate

Alginic acid derivative. Natural polysaccharide derived from brown seaweed.

Pharmacology

pharmachologic effect  - reparative, hemostatic, local anti-inflammatory.

In case of local application, it effectively helps to stop bleeding, eliminate inflammation and speed up healing processes, incl. in diseases of the gastrointestinal tract, including the anorectal region. Reduced signs of inflammation observed on the 7th day of treatment. On the 14th day, signs of inflammation usually disappear, improvement in the peripheral blood pattern is noted (increased hemoglobin level, red blood cells and a decrease in the number of leukocytes, a decrease in ESR).

Sodium Alginate

Description of the pharmacological action

Indications for use

   Anal fissures, proctosigmoiditis, colitis, bleeding and inflammation after colorectal interventions, chronic bleeding hemorrhoids, acute intestinal diseases with damage to the large intestine (like enterocolitis, hemocolitis, salmonellosis, dysentery).

Release form

   excipient powder; polyethylene bag (sachet) 1.2 or 3 kg;

Pharmacodynamics

   Hemostatic preparation for local use. It is a natural polysaccharide derived from brown algae. It has a pronounced hemostatic effect, has anti-inflammatory and reparative properties.

Use during pregnancy

   Perhaps rectal use during pregnancy and lactation according to indications.

Contraindications

   Hypersensitivity.

Side effects

   Allergic reactions.

Dosage and administration

   Apply rectally 2 times / day. The duration of treatment is 7-14 days depending on the severity of the disease.

Storage conditions

   In a dry, ventilated place (isolated from odorous substances and materials).

Shelf life

   60 months

Belonging to ATX-classification

V Other drugs

V03 Other miscellaneous drugs

V03A Other miscellaneous drugs

Sodium salt of alginic acid

Chemical properties

Sodium Alginate - an organic compound guluronic   and mannuronic acid linked by glycosidic linkages with branching. The natural polysaccharide is a white with a yellow tint powder, sometimes grayish. With water it forms a viscous colloidal solution; it is insoluble in alcohol and org. solvents. Depending on the number n, the molar mass varies from 32 to 600 thousand grams per mole. Acids of this kind are obtained from algae by treating the raw material with alkali solutions.

Substance applied:

• in the food industry as a gelling and thickening agent E401 , is a part of some desserts, homemade cheeses, cottage cheese products, sauces, canned products, ice cream;
• in perfumery and cosmetics;
• in the manufacture of certain drugs as a water-holding agent and thickener or as an active ingredient for local use.

Sodium Alginate Harm

When applying the drug topically or externally, it does not cause harm. Sodium Alginate is actively used in cosmetology, pharmacology and food industry. Substance is allowed in most countries of the world, including Russia and Ukraine. The tool does not cause allergic reactions, does not irritate the mucous membranes of the digestive tract. However, recent studies show that the systematic use of this chemical compound in food slows down the absorption of beneficial trace elements, iron, magnesium, calcium, and so on. The body does not receive enough vitamins and minerals that can affect health.

pharmachologic effect

Hemostatic, anti-inflammatory, reparative.

Pharmacodynamics and pharmacokinetics

Sodium Alginate has anti-inflammatory and reparative effects. Effectively stops bleeding, accelerates healing processes, reduces inflammation. Significant improvements occur after a week of systematic use of the drug, after 2 weeks the indices of the peripheral blood system improve, the level rises and decreases. ESR .

Indications for use

The drug is used:

• for treatment anal fissures , proctosigmoiditis bleeding;
• during rehabilitation after colorectal surgery;
• chronic bleeding