Ascorbic acid in ampoules. Ascorbic acid solution: instructions for use


Vitamin C  or vitamin C is known even to a child. Almost everyone knows that this vital element is necessary for the body to maintain immunity, prevent colds and viral diseases. An excellent prophylactic is tea with lemon, citrus fruits and berries, which include vitamin. But ascorbic acid can be ingested not only from food, but in the form of special preparations. Today, pharmacological companies offer vitamin C in ampoules. Due to this form of release, after the injection, the drug quickly enters the blood and has a great effect. In addition, it is widely used in cosmetology.

Benefits of ascorbic acid

A very important vitamin for the human body is organic substancewhich participates in most vital processes:

Getting into the blood of a person with food or as drugs, ascorbic acid is immediately included in all metabolic processes. If it is not enough in the body, many vital processes begin to suffer.

However, it is impossible to abuse and uncontrolled vitamin. The drug is capable of disrupting the integrity of the stomach and heavily load the kidneys. That is why experts recommend saturate the body with vitamin C through injections. Injections of ascorbic acid in the right doses will help the body and will not harm the gastrointestinal tract.

pharmachologic effect

With the introduction of ascorbic acid intramuscularly or intravenously easily, quickly and easily absorbed. In the body, it is transported by platelets and leukocytes. If you compare with blood plasma, then the concentration of vitamin in them is 30 times more.

Metabolism of the drug produced by the liver. It concentrates in the muscles and lungs, the pituitary and brain, the kidneys and the genitals, the liver and the pancreas. Excreted vitamin from the faeces and urine.

Indications for use

Vitamin C, released in ampoules, as injections applies under the following conditions and pathologies:

Contraindications

Despite great benefit  ascorbic acid for the body, in some diseases of its application is contraindicated:

Instructions for use of ascorbic acid in ampoules

To avoid negative consequences, injections of vitamin C should be done strictly in the dosage specified in the instructions.

Ascorbic acid is administered intravenously as a jet (within 2-3 minutes), and drip (25-30 drops per minute). When administered dropwise, from 50 to 100 ml of 0.9% saline or 5% glucose solution is taken as the basis.

Intramuscular injection  the solution is preheated to room temperatureand then they are inserted into a syringe and inserted into the needle deep into the muscle. For injection use 5% solution of the drug.

For the treatment of diseases, adults are prescribed from 1 to 5 ml of vitamin one to three times a day. For children, the daily dose of 5% of the drug is 0.6–1.0 ml. The course of treatment depends on the condition of the patient and the neglect of the disease.

Injections of ascorbic acid in ampoules should be administered after the examination by the attending physician.

special instructions

Since one of the key actions of ascorbic acid is the synthesis of corticosteroid hormones, it is possible risk of kidney stones. Therefore, treatment with this vitamin should take place under the control of the kidneys, adrenal glands and blood pressure.

With caution, the drug should be used with a high content of iron in the blood.

Excess vitamin levels can lead to a decrease in the work of the insular apparatus of the pancreas.

Side effects

In most cases, ascorbic acid is well tolerated by patients, however, in the process of taking the drug some side effects are possible:

  1. In the case of a quick injection, dizziness and fatigue.
  2. With intramuscular injection - pain in the injection site.
  3. In case of overdose, headaches and irritability.
  4. The increase in blood pressure due to the deterioration of capillary permeability.
  5. With prolonged use and excess doses - a violation of the kidneys, the development of nephrolithiasis or moderate pollakiuria.
  6. In patients prone to allergies, allergic reactions are possible, and even anaphylactic shock.
  7. Development of hypoprothrombinemia, glycosuria, leukocytosis, thrombocytosis, erythropenia.

Storage conditions and prices

Ascorbic acid in ampoules should be stored.  at air temperature from +5 ° С to +15 ° С in a place protected from direct sunlight. The drug should not be available for children. Shelf life of a vitamin for injection ranges from one and a half to two years.

Ascorbic acid is inexpensive. The price for a package of 10 ampoules of 2 ml of 5% solution is only about 30 rubles.

Ascorbic Acid for Face

Proved that vitamin C has a positive effect on the skintherefore, the solution produced in ampoules has long been used in cosmetology.

Proper use of ascorbic acid nourishes the skin and eliminates its redness and peeling, renews cells, improves complexion.

To maintain the skin in good condition, nourish and refresh it, the following procedure is recommended.:

  1. Two vials of the drug diluted with boiled water at room temperature in a 1: 1 ratio.
  2. The resulting solution to wipe the face, neck and décolleté morning and evening after water treatments.
  3. If after applying the solution there is a burning sensation, then you need to add another portion of water.

Excellent effect can be achieved if you use a mask consisting of vitamins C, E, A. The solutions are mixed and applied to the skin. The combination of ascorbic acid and fresh fruit will enhance the effect of the mask.

To remove cosmetic defects and improve the appearance of the skin professional cosmetologists conduct facial mesotherapy. During this procedure, a special preparation containing vitamins is injected under the skin with a very thin needle. Ascorbic acid injections nourish and protect cells from free radicals, help to improve blood circulation, and have a whitening effect. Trust this therapy should only proven and certified professionals.

Content of the article:

What are the properties of vitamin C. In which cases this vitamin is prescribed in the form of injections and how to determine the dosage.

Ascorbic acid (vitamin C) is a vital element that is involved in many processes and strengthens the immune system. Reception of an element is recommended for prevention of cold, treatment of viral and other diseases. Vitamin C is an element involved in the production of collagen, strengthens blood vessels, bone system and muscles. Substance comes only from food or by means of reception of special preparations.

Ascorbic acid is sold in several forms:

  • dragee;
  • pills;
  • ampoules.

Vitamin C in ampoules is a liquid form of ascorbic acid, characterized by a rapid flow into the blood and a great effect. The drug is taken with the requirements of the instructions and after the recommendation with a doctor.

Solution Dosage Form

The drug is sold in various volumes and dosages. Features of the release of vitamin C in ampoules:

  • In ampoules (volume) - 1, 2 and 5 ml.
  • The concentration of the active element - 5 or 10 percent.
  • Substance content on 1 ml - 50 mg.

Indications for use

Vitamin C in the form of injections appointed in the following cases:

  • diseases of scurvy or tuberculosis;
  • hypo- and aminominoz;
  • hard work (mental or physical);
  • lactation or active growth (for children);
  • hypothermia;
  • recovery period after illness or surgery;
  • parenteral or unbalanced nutrition;
  • gastrointestinal tract diseases - peptic ulcer, diarrhea;
  • recovery period after gastroectomy, bowel resection;
  • chronic intoxication of the body;
  • treatment of alcoholism and getting rid of smoking;
  • recovery from stressful conditions and injuries;
  • intoxication;
  • bleeding (liver, lung, nose);
  • radiation sickness and others.

Properties

Ascorbic acid enters the body with an injection and is carried with blood to all parts of the body. The greatest concentration is reached in the intrasecretory glands. Further vitamin has the following effect:

  • Regulates immune reactions, increases the body's resistance to viruses and infections.
  • It has anti-allergic and anti-inflammatory effects.
  • Participates in the exchange of cholesterol, amino acids, and also contributes to the accumulation of glycogen in the liver.
  • Accelerates the synthesis of hemoglobin in the body.
  • Participates in the process of tissue respiration.
  • Accelerates metabolic processes involving proteins, fats and carbohydrates.
  • Penetrates into platelets and leukocytes, and then - in all tissues.
  • After performing the functions assigned to it, it is excreted with feces, urine and sweat.

Doses of injections

To avoid the negative last, decide on the time of administration and dosage of vitamin C. The instructions for use in ampoules reads as follows.

For the treatment of diseases appointed:

  • Adults - 0.05-0.2 grams. If the composition is taken orally, the frequency of use - 4-5 times a day after eating. In the case of intravenous (intramuscular) administration, a 5% solution of sodium ascorbate is used. The dosage in this case is 1-5 ml, and the frequency of injections - 1-3 times a day, depending on the doctor's prescriptions and the purpose of the intake.
  • Children appointed to eliminate the deficit in the dosage 0.03-0.05 grams. In the case of injections, 0.6-1.0 ml of a 5% solution is injected once a day.

The duration of the course of treatment depends on the neglect of the disease, its type and the effect of preliminary complex treatment.


It is prescribed the drug and in order to prevent. Here the dosages are as follows:

  • Adults - 0.05-1 grams per day  (taken by mouth).
  • Children - when used parenterally 5%  volume solution 1-2 ml once a day. The course of treatment is 14-21 days.

When treating with the use of vitamin C, the limiting dosage should be taken into account:

  • For adults, a single dose - not more than 0.2 g, and daytime - not more than 0.5 grams.
  • In children, the maximum dosage depends on age. So, at 6 months, the marginal portion per day - 30 mgand at 14 years old 50 mg.

The introduction of ascorbic acid is possible:

  • inside;
  • intramuscularly.

Overdose

If you take more than one gram per day, the following effects are possible.

  • diarrhea;
  • heartburn;
  • nausea;
  • difficult urination;
  • hemolysis.

When the first signs of an overdose appear, the vitamin intake is terminated with the obligatory notification of the doctor about the incident.


Separate instructions

Participation in the synthesis of corticosteroid hormones - one of the key actions of vitamin C in ampoules. The instructions in this regard require:

  • control of blood pressure and adrenal glands;
  • avoidance of excess dosage of ascorbic acid due to the risk of kidney stones.

Please note a number of features:

  • Symptoms of scurvy may appear in the large-dosage period when the vitamin C is taken by newborns or their mothers.
  • Prolonged intake of ascorbic acid (in case of exceeding the norm) leads to the suppression of the function of the insular apparatus, which requires additional control.
  • With a high iron content is recommended intake of vitamin C in a limited dosage.
  • The presence of ascorbic acid in the blood affects a number of laboratory tests concerning urinary bilirubin, glucose, or other elements.
  • During the period of treatment, get behind the wheel or perform work requiring high concentration is not recommended.


Vitamin C not compatible  with a group of items, including:

  • doxapram;
  • aminophylline;
  • cefazolin;
  • belomitsin;
  • erythromycin;
  • chlordiazepoxide;
  • cefapirin;
  • nafillin;
  • methicillin and others.

The simultaneous intake of ascorbic acid and oral contraceptives leads to an increase in the bioavailability of ethinyl estradiol. It is also not recommended to combine vitamin C with anticoagulants or heparin due to a decrease in the potency of the latter.

In the matter of combining  ascorbic acid with other drugs, take into account a number of points:

  • Simultaneous intake with acetylsalicylic acid leads to the withdrawal of vitamin C from the body while at the same time delaying aspirin.
  • Treatment with concurrent use of ascorbic acid and sulfonamides guarantees rapid withdrawal. drugshaving an alkaline reaction.
  • Long-term intake of vitamin C sometimes leads to disruption of the interaction between ethanol and disulfiram. In addition, when exceeding the dosage of vitamin accelerates the withdrawal of meksiletin through the urogenital system.
  • Simultaneous reception with isoprenaline reduces the effect of the latter.


Contraindications and side effects

In the process of taking ascorbic acid, the following are possible. side effects:

  • The appearance and development of allergic reactions. In the most difficult situations, the risk of anaphylactic shock is high.
  • With long-term use of more than 0.6 grams per day, there is a high risk of developing moderate pollakiuria, and in the case of an increase in the daily ration, the development of nephrolithiasis and renal impairment.
  • The deterioration of capillary permeability, which is expressed by an increase in blood pressure, the appearance of microangiopathy.
  • Fatigue and dizziness (in case of a quick injection). With an overdose, irritability and headaches are possible.
  • Appearance pain sensations  at the injection site (intramuscular injection).
  • Development of erythropenia, thrombocytosis, leukocytosis, glycosuria, hypoprothrombinemia.

To receive vitamin C in the form of injections:

  • individual intolerance;
  • thrombophlebitis;
  • diabetes;
  • thrombosis;
  • increased blood clotting.

When prescribed in higher dosages, kidney function monitoring, pressure and glucose measurement are required.


Term and storage conditions

Ascorbic acid in capsules has a shelf life of one and a half to two years (depending on the manufacturer), after which its use is prohibited. Storage conditions:

  • the place must be inaccessible to children;
  • no direct hit of light;
  • temperature - 5-15 degrees Celsius.

As part of the packaging of vitamin C - ampoules and instructions for use.

The use of vitamin C in ampoules in cosmetology

The ampoule form of ascorbic acid is used not only in the treatment of "internal" diseases and the prevention of vitamin deficiency, but also for cosmetic purposes. Proven positive action  vitamin on the skin - it becomes more elastic, wrinkles disappear. The tablet form is also applied (after grinding into powder).

Due to the saturation of vitamin C, the skin perceives better peels, absorbs useful material  masks, faster responds to moisturizing and nourishing creams. Ascorbic acid in ampoules is more often used in professional cosmetology, but when used correctly, it provides no less results at home. Its action is:

  • improvement in complexion;
  • eliminating acne and blackheads;
  • skin cell renewal;
  • normalization of the nutrition of the epidermis;
  • elimination of peeling, redness, dilated capillaries.


To achieve the greatest results the following recommendations are recommended.:

  • The combination of vitamins E, C and A provides a more powerful effect. Elements are recommended to be mixed and applied as part of a common mask.
  • The use of fortified formulations in the presence of skin lesions is not recommended. You should not apply it in its pure form on the delicate eye area.
  • The combination of vitamin C and fresh fruit - the ability to enhance the effect of the mask.
  • Frequent use of ascorbic acid mixed with glucose is not recommended. If you choose a tool for processing, then it is necessary to give preference to the "clean" option.
  • When mixing ingredients in the process of making a mask, the use of metal containers is prohibited. Otherwise, ascorbic acid is destroyed. For the same reason, the use of metal spoons for stirring is prohibited.
  • Before applying the composition of the skin is recommended to clear of other cosmetics.
  • The optimal time for the mask - before bedtime.

When applying liquid vitamin in the area around the eyes, be careful. To achieve the result, mix ascorbic with additional ingredients - unsweetened yogurt, sugar and neroli oil. Apply the composition after complete dissolution using a cotton swab. The storage time of the mask is not more than a week.

If after application there is a burning sensation, redness of the skin, swelling and other problems, immediately wash off the mask warm water  and no longer use the composition. Allergic reaction is possible as in the case of the use of pure, and when applying mixed compounds.

Vitamin C positive effect on hair. Use of any mask with the subsequent addition of an ascorbic solution is allowed. The principle of application is simple. Apply the finished composition on the hair, hold it for 30 minutes, then rinse. To simplify the task, you can buy a ready-made mask and add vitamin C to it. As for mixing with shampoo, it does not make sense because of the short exposure time to the scalp.

Results

Ascorbic acid is a vitamin, the use of which helps to get rid of many health problems and strengthen the immune system. The main thing in this matter is not to show initiative and act in accordance with the recommendations of the attending physician. With this approach, you can avoid the risk of side effects  and overdose.

Vitamin C (ascorbic acid) is the most important substance for the normal functioning of the human body. Today, ascorbic remains the best way to strengthen the immune system, especially during cold seasons. In addition, this vitamin plays an important role in the process of production of collagen, which is necessary for maintaining good condition, restoring vessels, muscles, bone system, tissues and cells of the whole organism. At the same time, the human body itself does not produce this element. Vitamin C comes only from the food consumed.

Everyone knows the pills, pills of ascorbic acid. Many have taken them or taken regularly to maintain their health. Vitamin C ampoules are also used for therapeutic and prophylactic purposes. They, in particular, are prescribed when the body urgently needs additional administration of this substance. It should be noted that ampoules are also actively used in cosmetology.

When vitamin C is prescribed in ampoules - use instructions for use, indications for the drug, what? For complete information, we used the instructions for the drug attached to the package. On the basis of this description and compiled. However, before using the drug, be sure to read the instructions yourself.

Dosage Form

Is it possible for everyone to use vitamin C in ampoules (indications for use)?

As stated in the instructions for use, vitamin C injections are prescribed for conditions of increased need for it:

Hypo-or avitaminosis;
- Unbalanced or parenteral nutrition;
- With intense physical, mental work;
- Women for the period of lactation, as well as children during the period of intensive growth (if indicated);
-Patients after illness, the postoperative period;
- With the disease of tuberculosis, scurvy, burn disease, alcoholism, as well as during smoking;
- With prolonged hypothermia of the body, the presence of fever, hyperthyroidism, as well as chronic infections;
- In some diseases of the gastrointestinal tract: persistent diarrhea, peptic ulcer, as well as after resection of the small intestine and gastrectomy;
- With chronic intoxication with Fe, idiopathic methemoglobinemia.

Also, the drug is prescribed for prolonged stressful conditions, injuries, as well as during pregnancy, especially in multiple pregnancy, occurring against the background of alcohol or drug dependence.

How to dose vitamin C in ampoules (application)?

This drug is prescribed by the doctor after the examination. He also determines the course of treatment, as well as the route of administration (intravenously or intramuscularly). Usually the duration is 10 days. But, if necessary, the course can be extended, however, not earlier than in a month.

Single injection of the solution should not exceed 200 mg. Daily dosage should not exceed 500 mg.

Application in cosmetology

A solution of askorbinki in ampoules is also used to improve the condition of the skin. When applied externally in the form of masks, the complexion improves, fine wrinkles are reduced.

Regular application (2-3 times per week) significantly improves skin condition.
In addition, a solution of vitamin C is used to improve the condition of the hair. Just add the contents of the ampoule to your shampoo, then wash your hair as usual. With regular use, hair becomes strong, shiny, increases their elasticity.

What are the side effects of Vitamin C (in ampoules)?

With intravenous administration, caution should be exercised. Too fast process can cause dizziness, fatigue. In case of intolerance of the main component, allergic reactions may occur, accompanied by a skin rash, skin hyperemia.

With long-term treatment with large doses of the drug "Vitamin C (in ampoules)" instructions for use also warns that there may be signs of thrombocytosis, neutrophilic leukocytosis. Hyperprothrombinemia, erythropenia, or hypokalemia may occur.

What are the contraindications to the use of "Vitamin C (in ampoules)"?

The drug is not prescribed for individual intolerance. Intravenous administration is contraindicated in diabetes mellitus, thrombosis and thrombophlebitis, as well as in other conditions accompanied by increased blood clotting, or tendency to them.

Important!

At purpose of the increased doses of vitamin, the work of kidneys is surely carried out, regular measurement of arterial pressure is carried out. It is also necessary to monitor the level of glucose.

Patients with hypoacidic (anacidic) conditions, before the course of injections, are prescribed the introduction of hydrochloric acid with pepsin. This is necessary to eliminate the risk of destruction of vitamin C.

It must be remembered that in the treatment of this drug may be a distortion of some laboratory tests, namely: blood glucose, bilirubin, as well as transaminases and lactate dehydrogenase (LDH).

Without a doubt, vitamin C is an extremely important element for maintaining health and strengthening the immune system. Nevertheless, you need to understand that long-term use, or high doses of this substance lead to hypervitaminosis, which is no less harmful to the body than hypovitaminosis. Therefore, use this drug only on the recommendation of your doctor. Be healthy!

Name:  Ascorbic acid injection 10%

Active substance

Ascorbic acid * (Ascorbic acid *)

ATH

A11GA01 Ascorbic Acid (Vitamin C)

Pharmacological group

  • Vitamins and vitamin-like remedies
  • Composition and release form

    1 tablet contains ascorbic acid 50 mg; in a glass jar or bottles of 50, 100 or 200 pieces, or in a blister pack of 10 pieces, in a carton pack of 5 packs. 1 ml solution for injection — 50 or 100 mg; in 1 and 2 ml ampoules, in a carton of 10 pieces; 1 tablet - 50 mg; 50 pieces in a glass jar; 1 tablet for children - 25 mg; in a blister pack of 10 pcs., in a carton of 5 packs, or in a glass jar of 50 or 100 pcs. Powder - 2.5 mg; in paper bags.

    pharmachologic effect

    Pharmacological effects - compensating for vitamin C deficiency.

    Forms a system of ascorbic - dehydroascorbic acid, participating in the transfer of hydrogen and regulating the recovery of a number of metabolites and the activity of the monooxygenase system.

    Indications drug Ascorbic acid injection 10%

    Hypovitaminosis C, hemorrhagic diathesis, bleeding (nasal, pulmonary, hepatic, uterine), infections, intoxication, liver disease, adrenal insufficiency, sluggish healing wounds, ulcers, bone fractures, degeneration, increased physical and mental stress, pregnancy and lactation.

    Contraindications

    Thrombophlebitis, tendency to thrombosis, diabetes mellitus.

    Side effects

    Hyperglycemia, glycosuria, arterial hypertension.

    Dosage and administration

    Inside, for prevention, adults - 50-100 mg / day, children - 25 mg / day; for the treatment of children - 50-100 mg / day after meals; during pregnancy and lactation - 300 mg for 10-15 days, then - 100 mg / day. In / m, in / in - 1 ml of 10% or 1-3 ml of 5% solution. The highest dosage: single - no more than 200 mg, daily - 500 mg.

    Storage conditions of the drug Ascorbic acid injection 10%

    In the dark place.

    Keep out of the reach of children.

    The shelf life of the drug Ascorbic acid injection 10%

    Do not use beyond the expiration date printed on the package.

    Ascorbic acid solution: instructions for use

    Composition

    Active ingredient - ascorbic acid - 50 mg in 1 ml or 100 mg in 2 ml of solution; excipients: sodium bicarbonate, sodium sulfite anhydrous, water for injection.

    Description

    Transparent colorless or slightly colored liquid.

    Indications for use

    Treatment of hypo- and avitaminosis C (if necessary, rapid replenishment of vitamin C and the impossibility of oral administration).

    Clinical situations associated with the need for additional administration of ascorbic acid, including parenteral nutrition, diseases of the gastrointestinal tract (persistent diarrhea, resection of the small intestine, peptic ulcer, gastrectomy), Addison's disease.

    Contraindications

    Hypersensitivity to the drug. The administration of large doses - hypercoagulation, thrombophlebitis, tendency to thrombosis, diabetes mellitus, renal stone disease, deficiency of glucose-6-phosphate dehydrogenase.

    Carefully

    Hyperoxaluria, renal failure, hemochromatosis, thalassemia, polycythemia, leukemia, sideroblastic anemia, sickle cell anemia, malignant neoplasms.

    Dosage and administration

    Injection solution is administered intravenously or intramuscularly with therapeutic purpose  0.05 - 0.15 g (1-3 ml of 50 mg / ml solution), the maximum single dose - 0.20 g (4 ml), daily - 1 g (20 ml); children - 0.05 - 0.10 g / day (1 - 2 ml). The duration of treatment depends on the nature and course of the disease.

    Side effect

    From the side of the central nervous system: with rapid intravenous administration - dizziness, fatigue, with prolonged use of large doses (more than 1 g) - headache, increased excitability of the central nervous system, insomnia.

    On the part of the urinary system: frequent urination (with a dose of more than 600 mg / day), with prolonged use of large doses - the formation of urinary stones from calcium oxalate, damage to the glomerular apparatus of the kidneys.

    Since the cardiovascular system: with long-term use of large doses - a decrease in capillary permeability and deterioration of tissue trophism, increased blood pressure, increased blood clotting.

    Allergic reactions: skin rash, skin hyperemia, anaphylactic shock.

    Laboratory values: thrombocytosis, hyperprothrombinemia, erythropenia, neutrophilic leukocytosis, hypokalemia, hyperglycemia, glycosuria.

    Local reactions: pain at the site of intramuscular injection.

    Other: with prolonged use of large doses (more than 1 g) - inhibition of the function of the insular apparatus of the pancreas (hyperglycemia, glycosuria), hypervitaminosis, Na + and fluid retention, metabolic Zn 2+ and Cu 2+, with intravenous administration in large doses - threat abortion.

    Overdose

    Overdose symptoms occur with the introduction of ascorbic acid in large doses or for an extended period of time. The development of arterial hypertension, hyperglycemia, glycosuria, thromboembolic complications, and nephrolithiasis is characteristic.

    Aid measures include drug withdrawal and symptomatic therapy. There is no specific antidote.

    Interaction with other drugs

    Increases blood concentration of benzylpenicillin and tetracyclines; at a dose of 1 g / day increases the bioavailability of ethinyl estradiol (including part of oral contraceptives).

    Reduces the effectiveness of heparin and indirect anticoagulants.

    Increases the risk of crystalluria in the treatment of short-acting salicylates and sulfonamides, slows the kidneys excretion of acids, increases the excretion of drugs having an alkaline reaction (including alkaloids), reduces the concentration of oral contraceptives in the blood.

    Increases the overall clearance of ethanol, which in turn reduces the concentration of ascorbic acid in the body.

    Drugs quinoline series, calcium chloride, salicylates, glucocorticosteroids with prolonged use deplete reserves of ascorbic acid.

    With simultaneous use reduces the chronotropic effect of isoprenaline.

    With prolonged use or use in high doses may interfere with the interaction of disulfiram and ethanol.

    In high doses, increases the excretion of meksiletina kidneys.

    Barbiturates and primidone increase the excretion of ascorbic acid in the urine.

    Reduces the therapeutic effect of antipsychotic drugs (neuroleptics) - phenothiazine derivatives, tubular reasorption of amphetamine and tricyclic antidepressants.

    Pharmaceutically incompatible with aminophylline, bleomycin, cefazolin, cefapirin, chlordiazepoxide, estrogens, dextrans, doxapram, erythromycin, methicillin, nafcillin, benzylpenicillin, warfarin.

    Application features

    In connection with the stimulating effect of ascorbic acid on the synthesis of corticosteroid hormones, it is necessary to monitor renal function and blood pressure.

    With long-term use of large doses, the function of the insular apparatus of the pancreas may be inhibited, therefore it must be regularly monitored during treatment.

    In patients with a high content of iron in the body, ascorbic acid should be used in minimal doses.

    The administration of ascorbic acid to patients with rapidly proliferating and intensely metastatic tumors may aggravate the process. Ascorbic acid as a reducing agent can distort the results of various laboratory tests (blood glucose, bilirubin, activity of "liver" transaminases and lactate dehydrogenase).

    Use during pregnancy and lactation

    In pregnancy and lactation, apply only if the intended benefit to the mother outweighs the potential risk to the fetus and child. Theoretically, there is a danger to the child when the mother applies high doses of ascorbic acid (it is recommended that the nursing mother not exceed the maximum daily need for ascorbic acid).

    The minimum daily need for ascorbic acid in the II-III trimesters of pregnancy is about 60 mg. It should be borne in mind that the fetus can adapt to high doses of ascorbic acid, which a pregnant woman is taking, and then the development of a “withdrawal” syndrome is possible in a newborn.

    The minimum daily need during lactation is 80 mg. A mother's diet that contains an adequate amount of ascorbic acid, sufficient to prevent a deficiency in an infant.

    Influence on ability to steer the car and work with moving mechanisms:does not affect.

    Release form

    In 1 or 2 ml ampoules in a package No. 10, No. 10x1.

    Storage conditions

    In the dark place at a temperature of no higher than 25 C.

    Keep out of the reach of children.

    Shelf life

    1 year. Do not use after the expiration date.

    Pharmacy sales terms

    On prescription.

    Self-medication can be detrimental to your health.
    You must consult with your doctor, as well as read the instructions before use.