HPV is HIV infection. Viral infections in HIV-infected If there is HPV, will it show HIV positive

The similarity of abbreviations in medicine is not uncommon. But the overlap of terms or the overlap of HPV and HIV symptoms is not the worst thing. One disease can be a harbinger of another. The appearance of certain signs suggests that it was possible to prevent the development of a terrible diagnosis by taking timely measures. How medically interrelated are these types of infectious diseases?

HIV infection is often preceded by HPV infection

What is HPV or why papillomas appear

HPV is a sexually transmitted virus. Pathogenic cells enter the bloodstream. The infection has several varieties and manifests itself with a decrease in the activity of the immune system.

Key Features:

Widespread, according to statistics, about 90% are infected.
Leads to the appearance on the integument of the skin, including the intimate organs, papillomas, genital warts and other benign formations.
In the absence of adequate therapy, the growths degenerate into cancer.
There is a chance for self-healing, it happens in a year.

Note: HPV is an infectious disease with specific manifestations. There are several varieties of the virus, type 16 and 18 are considered dangerous.

Papillomas can degenerate into a cancerous tumor

Possible consequences:

degeneration of a benign tumor into a malignant one with the development of oncology;
suppuration, inflammation or damage to the papilloma;
the appearance on the body of multiple formations, their active growth (development of papillomatosis).

It is believed that if a person has everything in order with immunity, then the disease should not be treated, it will go away on its own, and warts that have appeared on the skin will disappear with it.

The virus causes the appearance of multiple papillomas on the body

But self-healing does not occur in 100% of cases. If papillomas have not disappeared after 10-12 months, they characterize themselves with rapid growth or cause serious inconvenience to the patient, symptomatic treatment is carried out, it consists in:

Taking medications that improve protective functions.
Cleansing and normalizing the work of vital organs and systems.
Removal by any available method of warts.

Human papillomavirus can be detected by performing appropriate diagnostic procedures. But often they are not required, since the doctor only needs to conduct a visual examination.

HPV has an unfavorable prognosis only under certain circumstances, there is a degeneration of the tumor, the development of oncology. In other cases, the patient can count on a cure.

The patient should use drugs to strengthen the immune system

HIV positive status: what is it

Immunodeficiency is the inability to resist pathogenic microorganisms. A person with such a diagnosis is unstable to viral agents and bacteria, easily becomes infected and often suffers from protracted, complicated diseases of various origins.

A virus, whose cells suppress natural protective functions, can cause a deficiency in immunity. Antibodies lose their ability to resist pathogens. As a result, the common cold becomes a fatal diagnosis for a person.

But HIV is not AIDS, but a condition that must be corrected with the help of drug therapy. It is customary to associate these diseases, although the difference between them is obvious.

Immunodeficiency prevents the body from resisting infections

Attention! AIDS is the final stage in the development of the immunodeficiency virus, patients with this diagnosis rarely live longer than 2 years.

The main signs and manifestations of the disease:

at the initial stage, a person begins to feel worse: there is lethargy, drowsiness, malaise;
there are signs of a respiratory or viral infection with a slight increase in body temperature;
an increase in lymph nodes in the inguinal, axillary or submandibular zone, accompanied by pain.

The disease is accompanied by an increase in lymph nodes

In both women and men, one non-specific symptom may be present - an increase in body temperature. At the same time, there are no other signs of the disease.

Often, any symptomatology is absent, which leads to late diagnosis. HIV does not manifest itself in any way, which means that a person has been a carrier of infection for a long time without knowing about it. To give the patient the correct diagnosis, you will need to donate blood for analysis and wait for the results.

Is there a connection between infections

Undoubtedly, HPV and HIV are two different diseases, but a closer study of the issue can reveal similarities between infections:

Lead to a decrease in the activity of the immune system.
Foreshadow each other.

HIV contributes to the development of dysplasia

The relationship between diseases is obvious to medical professionals. They managed to establish the following pattern:

people with a deficiency of the immune system are more likely to suffer from the manifestations of HPV;
however, in such patients, the human papillomavirus degenerates into cancer.

According to research, HPV in HIV-infected people often leads to the development of dysplasia, resulting in oncology. Most often, women suffer from this, faced with such a diagnosis as cervical cancer.

The relationship between the diseases is considered conditional and it cannot be argued that everyone who has had HPV or found several warts on the body is infected with HIV.

A blood test will help identify an infection

You can also find similarities during drug therapy: for the treatment of these diseases, agents that stimulate the immune system are used. It can be difficult to determine if HPV and HIV are related or not. But in order not to subsequently become a victim of a fatal diagnosis, when papillomas appear on the body, it is worth donating blood for HIV infection and determining your status.

For the causes of human papillomavirus infection, see below:

Hello dear guest of our site. In this article we will tell you how you can get tested for the human papillomavirus and what is needed for this.

Papillomavirus is an epitheliotropic pathogen that causes changes in mucous membranes and skin. Papillomas appear on the skin of the neck, face, upper half of the body, on the mucous membranes of the genital organs (cervix, vagina, vulva), on the skin of the genital organs (anogenital warts).

The virus is transmitted exclusively among the human population. At the same time, there are almost no people who would not be infected, so HPV is the most common sexually transmitted infection.

Other routes of transmission of the pathogen include the contact and household route, as well as from mother to child. The persons at risk include not only the decreed groups (prostitutes, drug addicts), but any person who is sexually active.

In the course of its activity, the human papillomavirus causes two types of changes:

Productive (when papillomas form);
Transforming (dysplasia of the mucous epithelium, malignant tumors).

The number of viruses with a high oncogenic risk is growing every year, thanks to the clarification of the DNA structure of various types of HPV.

Pathogens multiply in the squamous epithelium of the skin, resulting in skin warts and papillomas. Human papillomavirus infection is characterized by a variable course: subclinical, pronounced, latent.

Manifestations in persons of both sexes can be anogenital warts (cover the vestibule of the vagina, cervix, urethral opening, vaginal walls). In men, the localization is as follows: the foreskin, the glans penis, the skin of the scrotum.

The ability to cause a latent course in infected people is a feature of human papillomavirus infection. At this time, the pathogen is in an inactive state, only expression and transcription occurs, the formation of infectious viruses does not occur.

How to check for HPV in the body?

In the presence of vivid clinical manifestations, large condylomas, laboratory confirmation is not required. When confirmation of the diagnosis is required in the case of genital warts on the cervix, a Pap test is performed.

This is a smear taken from the cervix. The test has excellent diagnostic value, allowing you to detect malignant changes in the early stages. But sometimes the results are false negative (even up to 55% of cases) and also false positive (up to 15%).

The analysis for the human papillomavirus in men and women is carried out using the polymerase chain reaction. The method has high specificity and sensitivity: when determining the DNA of the virus, these indicators are up to 100%.

What is PCR?

This is a highly sensitive method for laboratory determination of the DNA of infectious agents. Material (blood, urine, saliva, sputum, amniotic fluid) is taken from the patient and the presence of DNA or RNA of the pathogen in it is determined. More often, a scraping smear from the mucous membrane of the cervix or urethra becomes the material for research.

The indications for the analysis are:

Warts and condylomas of the anogenital area;
If the cytological examination reveals epithelial dysplasia;
As a preventive screening study.

It is not allowed to take material from women during menstruation. The papillomavirus test can show normal cytological results if the virus DNA is present. In women, such an analysis result may indicate that after 2 years, 15-28% of patients may develop squamous and intraepithelial dysplasia.

If the results indicate viruses with a high risk of oncogenicity, and the patient is over 35 years old, one can think of a persistent infection and an increased risk of cervical cancer. A malignant tumor develops in 40-65% of cases.

If you have received questionable results of cytological analysis, then you should expect the detection of human papillomavirus in 75% of cases. Thus, the analysis makes it possible to correctly assess the contradictory result of cytological analysis.

After the course of treatment, a blood test should give a negative result.

Other ways to identify infection

Today, the most sensitive diagnostic method is the Daijin test. In addition to detecting the virus itself, the test allows you to determine the degree of its oncogenicity and belonging to one of 100 types.

Also, the doctor will be able to recognize clinically significant concentrations of the virus in the tissues taken for analysis, which is the primary diagnostic sign.

Analysis by this technique is generally accepted in the world community, since doctors, based on its results, can develop uniform protocols for the management of patients with HPV.
Material for research can be:

Scraping of epithelial cells of the cervical canal;
A similar scraping from the vagina and from the mucous membrane of the urethra;
Slide slide with already available material for analysis;
Patient tissue taken during biopsy.

The method is good as a screening quantitative analysis of a person when examining women, as well as in the case of an indeterminate result of the PAP test.
Decoding the analysis according to the Dajin test gives the following results:

Positive results in the absence of clinical manifestations. In this case, a re-analysis is prescribed after 6 months;
With a second positive test, it can be concluded that the virus is persistent. If the analysis is complemented by a clinical picture, the specialist can conclude about the risk of developing cervical cancer;
For women over the age of 30, with a negative result, it is recommended to repeat the study after a year.

The prices for tests that determine the presence of the virus in a person are injured. A polymerase chain reaction test will be inexpensive. If you decide to make a diagnosis based on the latest medical advances, and this is the Daijin test, you will have to pay several times the high cost.

HPV 16 and 18 types: a detailed description and methods of treatment

HPV type 16 and 18: what is it

These include:

early onset of sexual relations;
promiscuous sex life, frequent partner changes, unconventional sex - oral or anal;
the presence in the body of infections that cause sexually transmitted diseases;
abortions, gynecological diseases in women;
bad habits and stress;
chronic diseases, diabetes mellitus, HIV infection.

Entry ways into the body:

with intimate relationships, papillomas and condylomas are formed on the organs of the genitourinary system;
during household contact, if there is even the slightest wound or cut on the skin, the virus can easily enter the body through household items or personal belongings;
during labor - a baby may be born with growths in the mouth, larynx, genitals or perineum.

The main symptoms of HPV types 16 and 18 in men and women are:

growths in the form of warts - have a rough surface, rounded regular shape, no more than a centimeter in diameter, have a shade from flesh to dark;
in the form of papillomas - almost merge in color with the skin, they affect hidden places - armpits, groin areas, bends of the elbows, under the breast;
in the form of genital warts - grow and multiply very quickly, affect mucous membranes and skin genitals and anus.

What is the danger of HPV types 16 and 18:

are the most oncogenic among all HPV strains;
men from 18 to 25 years old fall into the risk group. Although the infection can remain in the body in a calm state for a long time, over time it can lead to infertility, impotence, erectile dysfunction;
more dangerous for women - according to research data, half of all cancerous pathologies of the cervix are associated with the presence of these viruses in the body. Even their detection is considered by gynecologists and oncologists to be a precancerous condition. Cause dysplasia of the cervix;
have a 100% chance of infection. They are mainly transmitted through saliva and blood, but there is a danger of penetration through microtrauma;
are highly resistant. Once in the body, they get used to the genome of the human cell, causing skin cancer.

How to diagnose and treat HPV types 16 and 18 in men and women

blood test for PCR;
Daigen test is the most modern and accurate type of diagnosis that allows you to study the DNA of the virus;
colposcopy for women;
cytological or histological examination.
a number of other diagnostic measures, if the diagnosis is in doubt.

Treatment primarily involves removing the build-up. The most modern methods are:

moxibustion with aggressive chemicals;
the use of a laser beam;
cryodestruction, cauterization with liquid nitrogen;
surgical operation with a scalpel.

Often at the reception, women are interested in whether it is possible to become pregnant if HPV type 16 is detected. If you are planning to have a baby and you are serious about it, then you should first receive treatment to eliminate the risk of infection of the baby.

Antiviral therapy, which is mandatory after the removal of growths, involves the use of modern medications aimed not only at suppressing the activity of the virus, but also at strengthening immunity, so that the body can eventually fight the disease on its own, eliminate the risk of relapse.

The best drugs against viruses include:

Acyclovir;
Epigen spray;
Isoprinosine;
Cycloferon;
Groprinosin.

In addition, immunomodulators and vitamin-mineral complexes are very important.

Also important:

do not have abortion;
lead a healthy sex life;
use contraception;
regularly undergo preventive examinations;
complete treatment of existing chronic diseases, do not start them.

Human papillomavirus type 56 in women and men

More than 60% of people on the planet are infected with the human papillomavirus. HPV 56 belongs to this family. The group of viruses is similar in symptoms and routes of infection, and differs only in oncogenic risk and cross-infection. A diagnosis of this type of HPV is scary for most people, and this is justified, since it provokes the development of neoplasia (cancer) in the cells of the reproductive organs, shortens life and its quality.

HPV type 56 is more often sexually transmitted and poses a significant threat to the human reproductive system.

Features of the type 56 virus

Human papillomavirus (Human papillomavirus) is a heterogeneous group of viruses that affects the skin and mucous membranes, for example, the cervix, anal canal, oral cavity. More than 600 types (strains) are known. HPV is the most common infection that is transmitted during sexual intercourse. It is so disseminated that all sexually active people can be carriers at any time in their lives. All strains can be divided into 3 groups:

HPV with low oncogenic risk (HPV 3, 6, 11, 13, 32, 34, 40, 41, 42, 43, 44, 51, 61, 72, 73);
HPV with medium oncogenic risk (HPV 30, 35, 45, 52, 53, 56, 58);
HPV with high oncogenic risk (HPV 16, 18, 31, 33, 39, 50, 59, 64, 68, 70);

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Routes of transmission and risk factors

HPV in 33% is spread sexually - the main route. Since during intercourse, the integrity of the epithelium is disrupted, which allows the human papillomavirus type 56 to penetrate and cause infection. There are also other ways of transmission of the virus:

baby in childbirth;
through touch - by contact (in public places through minor wounds, scratches on the skin).

The human papillomavirus is not transmitted by the airborne route, i.e. through the air and touching objects, for example, a doorknob, a handshake.

People with weakened immune systems, uncontrolled sex life and poor hygiene are at risk of contracting HPV type 56.

Human papillomavirus exists in the body in a latent state. In 90% of cases, within 6-12 months, the body independently copes with the infection - self-healing. The manifestation of symptoms and the transition to a chronic disease with frequent exacerbations occurs if the following risk factors are present:

decreased immunity or immunosuppression;
overwork, chronic stress;
a large number of sexual partners;
earlier onset of sexual activity;
HIV infection;
the presence of other STDs;
deficiency of nutrients;
drug use, smoking, psychoactive substances;
genetic predisposition;
pregnancy.

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Risks for men and women

Type 56 belongs to the group of oncogenic risk, affecting the human reproductive system, causing genital infection in women and men. Both sexes, regardless of sexual orientation, will be infected with at least one type of HPV in their lifetime. For men, HPV is not dangerous, as it is not associated with health risks. Genital warts are rare in men infected with the virus. In women, on the contrary, the frequency of occurrence is quite high - 80%. Also, the type 56 virus in women leads to erosion, dysplasia of the cervix - pathological changes in the normal epithelium of the internal organ. The DNA of the virus, by weakening the human immune system, activates the appearance of bacterial, fungal, and other viral infections.

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HPV symptoms

After an incubation period, which on average lasts from 15 days to several years, symptoms of infection appear in only 10% of cases. It is generally accepted that there are no symptoms of the disease. Despite the fact that the virus causes changes in the cells of the skin, mucous membranes, they are insignificant and do not cause anxiety and complaints in the patient. Papilloma virus 56 causes noticeable changes in the presence of risk factors. Warts or genital warts, which can be found around the anal canal, on the penis, scrotum in men. The same condylomas appear on the female genitals - on the labia majora and small labia, on the clitoris, and also in the urethra. Their appearance can be accompanied by itching and burning.

HPV type 56 provokes the growth of intimate warts, and they are a source of physical discomfort.

Condylomas - formations that protrude above the surface of the skin or mucous membrane on the leg. They have a different color range - from pale pink to dark brown. They tend to merge and grow rapidly. They are characterized by growth not only above the surface of the skin, but also grow inward, which makes it difficult to remove.

The US Centers for Infectious Disease Control claims that HPV infection causes cancers in the cervix, vagina in women and penis cancer in men. Also HPV 56 type causes cancer of the anal canal, oropharynx. But dysplasia is of particular importance first, and then cervical cancer.

The papillomavirus resembles sexually transmitted pathogens by its mechanism of spread and typical localization of manifestations. Located, as a rule, in the genital area, infection most often occurs through sexual contact. However, unlike conventional STDs, papillomavirus can be obtained in other ways. How else is HPV different from these diseases?

Papilloma and HIV are primarily associated with the fact that the latter is accompanied by a significant decrease in immunity and can cause the manifestation of the former. As you know, AIDS over time suppresses the human immune system, as a result of which the body is unable to resist HPV. Since up to 90% of the population becomes infected with papilloma, sooner or later characteristic skin growths begin to appear in most HIV-positive patients. Because of this, it is recommended to carry out an analysis for HIV infection with the manifestation of papillomavirus.

MINISTRY OF HEALTH OF THE RF: The papillomavirus is one of the most oncogenic viruses. Papilloma can become melanoma - skin cancer!

Thus, both pathogens are associated with the work of the immune system and through it interact with each other. The difference between HIV and HPV is that the first affects the body's immune cells, and the second is a skin disease and is activated only when immunity is reduced.

HPV and cytomegalovirus

Papillomavirus and CMV are very similar - infection occurs in similar ways, rashes in the active phase appear in the same parts of the body. However, CMV belongs to herpes viruses - the nature of microorganisms is the main difference between HPV and CMV.

In addition, while papillomatosis manifests itself only in the form of skin lesions, the symptoms of cytomegalovirus are similar to acute respiratory infections. The temperature rises, the head hurts, and weakness appears. Against the background of CMV, pneumonia can develop. Both viruses can lead to various diseases of the genital organs, up to cervical cancer.

HPV and chlamydia

Chlamydia is not a viral infection. The causative agents that cause it are bacteria. Like papillomatous infection, in some cases, this pathogen can spread outside the reproductive system and manifest itself in a variety of areas of the body. There are cases of chlamydial pneumonia, conjunctivitis, etc.

Another similarity of diseases is that they are difficult to detect while they are in the passive stage. Chlamydia may not manifest itself for a long time after infection. Again, everything rests on immunity - like HPV, chlamydia begins an aggressive attack on the human body only during the period of weakening of the defenses. This is especially true for HIV-infected: they are most susceptible to infection with sexually transmitted diseases.

MINISTRY OF HEALTH WARNING: “Papillomas and warts can become melanoma at any time. "

The relationship between papillomavirus and HIV infection

What is HPV or why papillomas appear

HPV is a sexually transmitted virus. Pathogenic cells enter the bloodstream. The infection has several varieties and manifests itself with a decrease in the activity of the immune system.

Widespread, according to statistics, about 90% are infected.
Leads to the appearance on the integument of the skin, including the intimate organs, papillomas, genital warts and other benign formations.
In the absence of adequate therapy, the growths degenerate into cancer.
There is a chance for self-healing, it happens in a year.

Note: HPV is an infectious disease with specific manifestations. There are several varieties of the virus, type 16 and 18 are considered dangerous.

degeneration of a benign tumor into a malignant one with the development of oncology;
suppuration, inflammation or damage to the papilloma;
the appearance on the body of multiple formations, their active growth (development of papillomatosis).

Taking medications that improve protective functions.
Cleansing and normalizing the work of vital organs and systems.
Removal by any available method of warts.

Human papillomavirus can be detected by performing appropriate diagnostic procedures. But often they are not required, since the doctor only needs to conduct a visual examination.

HPV has an unfavorable prognosis only under certain circumstances, there is a degeneration of the tumor, the development of oncology. In other cases, the patient can count on a cure.

HIV positive status: what is it

But HIV is not AIDS, but a condition that must be corrected with the help of drug therapy. It is customary to associate these diseases, although the difference between them is obvious.

Attention! AIDS is the final stage in the development of the immunodeficiency virus, patients with this diagnosis rarely live longer than 2 years.

The main signs and manifestations of the disease:

at the initial stage, a person begins to feel worse: there is lethargy, drowsiness, malaise;
there are signs of a respiratory or viral infection with a slight increase in body temperature;
an increase in lymph nodes in the inguinal, axillary or submandibular zone, accompanied by pain.

In both women and men, one non-specific symptom may be present - an increase in body temperature. At the same time, there are no other signs of the disease.

Is there a connection between infections

Undoubtedly, HPV and HIV are two different diseases, but a closer study of the issue can reveal similarities between infections:

Lead to a decrease in the activity of the immune system.
Foreshadow each other.

The relationship between diseases is obvious to medical professionals. They managed to establish the following pattern:

people with a deficiency of the immune system are more likely to suffer from the manifestations of HPV;
however, in such patients, the human papillomavirus degenerates into cancer.

The relationship between the diseases is considered conditional and it cannot be argued that everyone who has had HPV or found several warts on the body is infected with HIV.

For the causes of human papillomavirus infection, see below:

How to treat papilloma virus? How is it dangerous? Does it look like HIV infection? What is fraught with, how to deal with it? Help me please

Removal of cells altered by the human papillomavirus can be performed by any known surgical method (cryodestruction, laserconization, diathermoconization or amputation of the cervix):

The most effective and promising is the complex combined method of therapy, when the local removal of the external manifestations of HPV is carried out against the background of systemic and local antiviral treatment.

Combination therapy includes: local destructive treatment ( surgical removal) in combination with the use of various systemic nonspecific antiviral and, if necessary, immunomodulatory drugs, which help to suppress the activity of HPV up to its complete destruction, reducing the frequency of relapses to isolated cases, which clinicians most often associate with HPV reinfection from a sexual partner.

These drugs include the following:

Allokin-alpha;
Viferon;
Genferon;
Isoprinosine;
Immunomax;
Likopid;
Epigenes intimacy.
Allokin-alpha
Pharmacotherapeutic group: antiviral, immunomodulatory agent.
Release form: lyophilisate for preparation of solution for injection in ampoules, 3 in a package.

Effective in the treatment of chronic papillomavirus infection caused by oncogenic human papillomaviruses.

In monotherapy, Allokin-alpha is recommended for the treatment of human papillomavirus infection caused by oncogenic types of the virus, in the absence of lesions of the cervix and anogenital region. As part of complex therapy - for the treatment of various forms of lesions of the cervix and anogenital area caused by oncogenic HPV types.

Viferon
Pharmacological groups: interferons.
Release form: ointment, gel, suppositories.

It combines well with antiviral agents and interferon inducers, is effective against HPV as a local immunomodulatory agent as part of complex therapy when HPV is combined with herpes virus or chlamydial, mycoplasma infection.

I had sexual intercourse with my boyfriend, I was his first, and he was my second. A month later, he found out that he had HIV and no more diseases, I tested negative for HIV, but they found a dangerous type of HPP, erosion and a cyst. Has passed for a biopsy to go to an appointment soon and I'm afraid that there is cancer. How could it be that he was found to have HIV, but I do not, I have HP, but he does not. How can this be, tell me, maybe someone had something similar?

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6 months have passed since the PA?
Is he a drug addict?

I have HPC oncogenic, erosion. increased erosion I am treated

are you sure you are the first?

As far as I am aware, antibodies to HIV in the tests are determined only 6 months after infection. Therefore, the analysis must be retaken six months later. If you've used a condom correctly, the risk is small.
HPV is also transmitted through a condom. But it may not have passed on to the guy.

now a new test detects HIV immediately.

Hiv. detected only after 6 months after infection.
6 months have passed since the PA?
Is he a drug addict?
Sympathize with you. The most important thing is to start getting supportive care as soon as possible.

He's still gay or bi, maybe just a girl first, not a girl who knows him.

Well, what is there. Contagion does not stick to contagion. My grandfather used to say that.

Is the HPF also vineric? Sister just like that. I'm shy to ask

And inerical is it from the word blame?))

are you sure you are the first?

HIV isn't just transmitted through sex. They could have given him a blow job. and so through the blood, a small cut

i dated a guy for half a year who had HIV and hepatitis C. The first analysis showed nothing. And then a few years later I retaken, I didn't have HIV, but hepatitis C, apparently, was transmitted. Although, they say that supposedly they cannot get sick through sex. But that 100% guarantee is not there, maybe somewhere else I picked it up, who knows. And so, it happens, people live for years and nothing is passed on to anyone. On the Internet, I read a lot of discussions about HIV, that there is no evidence that you can somehow get it. And about HPP - in my youth they found him and said that it was not treated. But in adulthood, she retaken tests for latent infections many times and was never found again. I asked the doctors and they said that it could go away on its own, such cases are not uncommon. Moreover, there were also two bad types and they once cauterized erosion for me. Now, apart from hepatitis C, I just have perfect health. I don’t even know whether it is worth treating him, or, somehow, I’m shortening my life. And whether he is being treated or is it a divorce for money.

can you give me hepatitis C?

why do you need it?))) I'm telling you that it's not even clear how people get infected with it. My friend had a boyfriend with hepatitis C - nothing was transmitted to her and the doctor said that such a probability is negligible. But my distant relative in another city also caught hepatitis C from somewhere, although he does not drink, does not smoke, is not a drug addict, and in general he is already many years old, so it is unlikely that he mess with everyone randomly))) Where does this disease come from - generally xs. And the disease is strange, nothing manifests itself, only in the test results it is visible, well, life shortens a little.

HIV and hvp linked or not

HUMAN PAPILLOMA VIRUS (HPV). RESEARCH HISTORY AND RELATIONSHIP WITH HUMAN IMMUNODEFICIENCY VIRUS (HIV)

Karp Tatiana Dmitrievna

2nd year student, Department of Medical Biophysics, Far Eastern Federal University, RF, Vladivostok

Reva Galina Vitalievna

scientific adviser, Ph.D. honey. Sci., Professor, FEFU, RF, Vladivostok

Currently, more than 120 types of papillomaviruses have been identified, of which 70 types are described in detail. It has been established that papillomaviruses have a type and tissue specificity, which means that each type is capable of infecting tissue characteristic of its localization. For example, HPV type 1 causes plantar warts, HPV type 2 causes common warts, HPV type 3 causes flat warts, etc.

Human papillomavirus (HPV) belongs to subgroup A, the papovirus family (Papoviridae). HPV is spherical in diameter up to 55 nm. A capsid with a cubic type of symmetry, forms a geometric figure - an icosahedron, built of 72 capsomeres. The genome of HPV is presented in the form of a cyclically closed double-stranded DNA with a molecular weight of 3-5 mD. Isolated DNA has infectious and transforming properties. One of the DNA strands is considered coding and contains information about the structure of viral proteins. One coding strand contains up to 10 open reading frames, which, depending on the localization in the genome, divide the early and late ones.

The HPV virion contains two layers of structural proteins, designated by the letter E. The early region includes genes E1, E2, which are responsible for viral replication. The E4 gene is involved in the maturation of viral particles. HPVs of a high degree of oncogenic risk encode the synthesis of capsid proteins E5, E6 and E7, which are involved in malignant transformation. The interactions E6 / p53 and E7 / Rv1 lead to deformation of the cell cycle with a loss of control over DNA repair and replication. Thus, polymorphism of the gene encoding p53 is a genetic predisposition for the active development of HPV, followed by cell malignancy. Late genes L1 and L2 encode viral capsid proteins.

Internal proteins associated with DNA are cellular histones, and capsid proteins are type-specific antigens. HPV reproduction occurs in the nucleus of cells, where viral DNA is present as an episome. This is the first feature that distinguishes HPV from other oncogenic DNA viruses that can insert their genome into the DNA of a transformed cell.

The second feature of HPV is that the viral gene responsible for the replication of cellular DNA can be transcribed, causing the host cell to divide with the HPV, which leads to a productive type of inflammation, regardless of the ability of the host cell to regulate the expression of the viral genome.

The HPV genome contains hormonal receptors for progesterone and glucocorticoid hormones, which explains the dependence of the course of PVI on the hormonal homeostasis of a woman.

According to the International Agency for Research on Cancer classification, HPV 16, 31, 51 and 18 are classified as “carcinogenic to humans”, while HPV 66 is classified as “possibly carcinogenic”.

Multivariate analysis suggests that the number of sexual partners during a lifetime is the determining role in HPV infection. This reinforces the idea that the most appropriate age for HPV vaccination is the period prior to sexual activity. Living with a partner had a protective effect against high-risk HPV infection.

The relationship between HPV and HIV. After 30 years of an HPV epidemic, there are about 2 new infections for each treatment and no effective vaccine. New measures are needed with a biologically targeted co-factor for HIV infection. Associations have been established between sexually transmitted infections, especially herpes simplex virus type 2, and the acquisition of HIV. A number of recent studies have documented the link between human papillomavirus (HPV) and HIV infection.

HPV is the main cause of cervical cancer, rapidly acquired after sexual debut, and infections with multiple genotypes are similar. This makes HPV a widespread sexually transmitted infection (STI) worldwide. There are approximately 40 HPV genotypes that affect the human genital tract, they are divided into 2 groups depending on the oncogenic potential: high risk oncogenic and low risk without oncogenic genotypes. Symptoms of infection are rare and usually present as anogenital warts. There are two effective vaccines that offer protection against HPV. The bivalent vaccine is directed against HPV 16 and 18 types, and the quadrivalent vaccine against HPV 16, 18, 6, 11. Evidence has been provided that both vaccines cross-work on types for which there is no vaccine (especially HPV 31, 33 and 45).

Collecting, evaluating and synthesizing the available data on the association of HPV with HIV acquisition could provide scientists with an important resource for assessing the potential role of HPV in the HIV pandemic. The aim of the study was to accumulate and evaluate observational data, which trace the relationship between the prevalence of HPV and HIV infections, and to estimate the proportion of HIV infections caused by HPV infections.

This systematic literature review provides the first published summary of the association between HPV prevalence and HIV infection. 7 out of 8 studies have shown a link between these infections, a high proportion of HIV infections are associated with any HPV genotype. Summarizing the studies in women, an increase in the risk of HIV infection in the presence of HPV genotypes was found almost twice, the same association was found in two studies in men.

The association between HPV prevalence and increased risk of HIV infection is biologically plausible. It has been shown that the E7 protein of HPV 16 type reduces the number of epithelial adhesion molecules, namely E-cadherin (cell adhesion is the connection of cells with each other, which leads to the formation of certain correct types of histological structures specific for these types of cells. The specificity of cell adhesion is determined by the presence on the surface of cells of proteins of cell adhesion - integrins, cadherins, etc.).

This potentially increases the permeability of HIV in the genitals. The cells lining the reproductive tract contain Langerhans cells that can assimilate HIV, preventing further spread of the infection. The immune response to HPV is mediated by T-lymphocytes, this response may increase the risk of contracting HIV, since T-lymphocytes are the main target cells for HIV. An increase in the number of these cells has been seen in HPV-infected cervical tissues. An increase in the cytokines IL-Iβ, which activates a promoter region in the HIV genome, was also found in women with abnormal cervical cytology infected with HPV.

To summarize, we can say that studies in women have shown a strong relationship between the prevalence of HPV and HIV infection. The HPV vaccine is very effective in the primary prevention of HPV and subsequent cancer of the cervix and genital warts. Refinement of the results presented in this study is needed in order to assess the potential for HPV vaccine to influence the incidence of HIV.

The article was written based on materials from the sites: www.zppp.saharniy-diabet.com, bolezni.com, otvet.mail.ru, www.woman.ru, sibac.info.

Although HPV and HIV are sexually transmitted, you have no medical connection. However, behaviors that put you at risk of contracting HIV can put you at risk for HPV.

What is HPV?

More than 150 related viruses are collectively referred to as human papillomavirus (HPV). HPV is the most common sexually transmitted infection (STI) and can cause other health conditions, including genital warts and cervical cancer.

About 79 million people in the United States have HPV It is so common that most sexually active people contract at least one type of HPV during their lifetime.

What is HIV?

HIV is sexually transmitted. The virus attacks and destroys CD4 positive T cells. blood cells that protect your body by looking for and fighting off infection. Without healthy T cells, your body has little protection against opportunistic infections.

If you don't have treatment, HIV can lead to AIDS.

HPV signs

Often, people with healthy immune systems are able to fight HPV infections on their own without experiencing noticeable health problems.

When the body is unable to fight off HPV, symptoms can manifest as genital warts. You can also develop warts in other parts of your body, including:

HPV primarily increases the risk of cervical cancer, but increases the risk for other cancers. This includes cancer:

HPV cancers can take years to develop. Because of this, it is important to get tested regularly. Women should be regularly screened for cervical cancer.

HIV symptoms

People with HIV are often unaware they have the virus. It does not cause any physical symptoms at all. In some cases, you may experience symptoms for up to one to six weeks after infection.

fever
enlarged lymph nodes
joint pain

Risk Factors What are the risk factors for HPV and HIV?

You can compress any virus when you come into direct contact with whoever has it. Viruses can enter your body through any opening or break your skin.

You can get HPV by having unprotected vaginal, anal, or oral sex. HIV can be transmitted in a variety of ways, including blood, breast milk, or sexual fluids. Penetration during sex is not required for HIV infection; perhaps all that is required may be previously exposed to the seminal or vaginal fluids of an infected person. Vaginal, oral, and anal sex increase the risk of HIV infection.

Another method of transmission is through the use of injection needles.

Having an STI increases the risk of contracting HIV, and people with HIV are more prone to HPV.

Diagnosis How are HPV and HIV diagnosed?

HPV diagnostics

In some people, the development of genital warts may be the first indicator of HPV infection. Others may find out they have HPV when they develop more serious conditions, such as cancer.

Your doctor can usually diagnose HPV only through a visual examination of your warts. If the warts are difficult to see, a test using a vinegar solution turns them white so the warts can be identified.

A Pap test can determine if cells from the cervix are abnormal. Certain types of HPV can also be identified using a DNA test on cells of the cervix.

HIV diagnostics

It can take up to 12 weeks for your body to develop antibodies to the virus. HIV is usually diagnosed with blood or saliva tests, but these tests can have false negatives if you take them too quickly. This means that the test result comes back negative even if you have a viral infection. A newer test checks for a specific protein that will be present shortly after you become infected.

You can also use a home test that only requires a gum swab. If you get a negative result, you should check back after three months. If it's positive, see your doctor to confirm the diagnosis.

The earlier you are diagnosed and start treatment, the better. CD4 count, viral load, and drug resistance tests can help you figure out what stage of your illness you have and how best to approach treatment.

Treatment How are HPV and HIV treated?

Treatment options for HPV

There are no specific treatments for HPV, but it often clears up on its own. Treatments are available for genital warts, cancer, and other conditions that result from HPV.

HIV treatment options

HIV infection has three stages:

People often describe the symptoms of acute HIV infection as having the “worst flu”. Typical flu symptoms are common at this stage.

HUMAN PAPILLOMA VIRUS (HPV)

WHAT IS HPV?
HOW TO DIAGNOSE HPV?
IS IT POSSIBLE TO PREVENT HPV?
HOW TO TREAT HPV INFECTION?
HIGHLIGHTS

WHAT IS HPV?
There are over 100 viruses known as human papillomavirus (HPV). They are widespread. One study found HPV in 77% of HIV-positive women. HPV is easily transmitted during sexual activity. It is estimated that 75% of all sexually active people aged 15 to 49 get at least one type of HPV infection.
Certain types of HPV often cause warts on the hands or feet. Infection in the hands and feet is usually not spread through sexual activity.
Certain types of HPV cause genital warts (warts) on the penis, vagina, and rectum. People living with HIV can get complications such as ulcers in the rectum and neck. HPV can also cause problems in the mouth, tongue, or lips.
Other types of HPV can cause cell overgrowth known as dysplasia. In men and women, dysplasia can develop into anal cancer, cervical cancer, and penis cancer.
Dysplasia around the anus is called anal intraepithelial neoplasia (AIN). Anal intraepithelial neoplasia is the proliferation of new abnormal cells in the fold of the anus.
Cervical dysplasia is called cervical intraepithelial neoplasia (CIN). AIN or CIN is more common in people with HIV infection than in people who are HIV negative.

HOW TO DIAGNOSE HPV?
To identify HPV, doctors first of all look at the problems that arise with HPV: dysplasia or condyloma.
Dysplasia can be detected by cytological examinations of smears stained by Pap smears. They are usually used to examine the cervix in women. They can also be used to examine the anus in men and women. A swab from the study area is taken to collect cells. The cells are placed on glass and viewed1 under a microscope.
HPV reflex testing is used when the Pap smear results are not clear. Testing can identify those who need more thorough evaluation or treatment. Reflexive testing determines what types of HPV are present and can show if aggressive treatment is required.
Some researchers believe that anal and cervical swabs should be performed annually in groups of people at increased risk:
people who have had receiving anal sex
women who have had cervical intraepithelial neoplasia (CIN)
those with less than 500 CD4 cells.
However, other researchers believe that a thorough physical examination, like the anal Pap test, can detect many cases of anal cancer.
Warts can appear in the period from several weeks to several months after the risk of getting HPV. Warts may look like small bumps. Sometimes they are fleshy and look like small cauliflower. They can get bigger over time.
Your doctor can usually tell on a physical exam if you have genital warts. Sometimes an anoscope instrument is used to view the anal area. If necessary, tissue from the suspicious wart can be taken for examination under a microscope. This is called a biopsy.
Warts are caused by a different type of HPV than the one that causes cancer. But, if you have warts, you may have other types of HPV that can cause cancer.

IS IT POSSIBLE TO PREVENT HPV?
There is no easy way to know if someone is infected with HPV. People who do not have any signs or symptoms of HPV infection can transmit the infection.

Condoms do not completely prevent HPV transmission. HPV can be spread by direct contact with infected areas that are not covered by a condom.
Sexually active men and women with HIV may want to have regular anal and / or vaginal Pap smears to check for abnormal cells or early signs of warts. If the result is positive, follow-up should be continued in order to understand whether treatment is required.
The Gardasil vaccine was approved in 2006. However, it has not been tested or approved for people already infected with HPV.

HOW TO TREAT HPV INFECTION?
There is no direct treatment for HPV infection. In some people, the HPV infection "disappears" (they "heal"). They can then be infected with HPV again. However, dysplasia and warts can be removed. There are several ways to do this:
Burning with an electric needle (electrocautery) or laser
Freezing with liquid nitrogen
Cutting out
Treating them with chemicals
Other less common treatments for warts are 5-FU (5-fluorouracil) and interferon-alpha. A new drug, imiquimod (Aldara®), has been approved for the treatment of genital warts. Cidofovir (Vistide®), originally developed to fight cytomegalovirus (CMV), also helps fight HPV.
HPV infections can last for a long time, especially in HIV-positive people. Dysplasias and warts may recur. They should be treated when found to reduce the chances of problems spreading or reoccurring.

Infections that develop with HIV

What are opportunistic infections? What are opportunistic infections? How is opportunistic infection prevention carried out? You will find the answers to these questions in the article.

This is the name for diseases that can occur in the late stages of HIV infection with a weakened immune system. Some of them develop only with HIV infection, while others, in combination with HIV, take on a particularly severe, life-threatening form.

By itself, HIV does not cause illness or death; the danger is posed by opportunistic diseases that develop against the background of HIV infection. These diseases are caused by infections that are harmless or almost harmless with normal immunity, but with the development of immunodeficiency can lead to serious problems. They are also called HIV-associated diseases.

Contrary to popular belief, a simple cold or flu is no more dangerous for HIV-positive people than for everyone else.

Not all infections are opportunistic and there are not so many of them.

What are opportunistic infections

Bacterial pneumonia. Bacterial infection with HIV infection can develop into bacterial pneumonia. The risk is increased if you smoke or use drugs. Prevention of PCP (Pneumocystis pneumonia) also helps prevent bacterial pneumonia. The bacteria can also cause severe gastrointestinal upset.

Human papillomavirus (HPV) Is a widespread genital infection caused by a group of viruses called human papillomavirus. HPV is easily passed from one person to another through sexual contact. The virus causes genital warts, which look like bumps on the surface of the penis, vagina, or anus. Certain types of HPV can also cause cervical cancer. The virus can be passed from one person to another even in the absence of symptoms. HPV can be transmitted to everyone, but in people with HIV, the disease is much more serious, can recur many times and last for a long time. Medicines from HPV does not exist, but there are numerous ways to remove warts and treat dysplasia of the cervix and anus caused by HPV.

Histoplasmosis caused by a fungus that lives in the soil, into which it enters through bird excrement or other organic matter... The fungus enters the human body by inhaling dust containing this fungus. Many people are exposed to the fungus, but usually the disease does not develop in a healthy body. Usually histoplasmosis

HPV is easily passed from one person to another through sexual contact. The virus causes genital warts, which look like bumps on the surface of the penis, vagina, or anus. Certain types of HPV can also cause cervical cancer. The virus can be passed from one person to another even in the absence of symptoms. HPV can be transmitted to everyone, but in people with HIV, the disease is much more serious, can recur many times and last for a long time. There is no cure for HPV, but there are many ways to remove warts and treat HPV-related cervical and anus dysplasia.

Histoplasmosis it is caused by a fungus that lives in the soil, into which it gets through bird excrement or other organic matter. The fungus enters the human body by inhaling dust containing this fungus. Many people are exposed to the fungus, but usually the disease does not develop in a healthy body. Histoplasmosis usually affects the lungs, but in people with weakened immune systems, it can spread to the entire body. Histoplasmosis is not transmitted from person to person. Histoplasmosis is treated with antifungal drugs.

Candidiasis (thrush) usually affects the mouth, larynx, lungs, and / or vagina. The fungi that cause candidiasis are naturally present in the human body, and they are the cause of most cases of the disease. It is common in HIV-negative people, but HIV-positive people are much more susceptible to it. Severe cases of candidiasis occur in people with an immune status below 200 cells / ml. Candidiasis is treated with antifungal drugs, but repeated cases are common.

Mycobacterium avium complex - a disease caused by Mycobacterium avium and Mycobacterium intracellulare. These two similar types of bacteria are found everywhere in water, soil, dust, and food. The infection can affect anyone, but HIV-positive people are at much higher risk of developing serious illness. The bacteria can infect specific areas or spread throughout the body. There is a wide range of drugs available to prevent and treat Mycobacterium avium complex and to prevent recurrent outbreaks.

Cryptococcal meningitis. It is caused by the fungus Cryptococcus, which is normally found in soil through bird excrement. Cryptococcus enters the human body by inhalation of dust in which this fungus is present. Many people are exposed to the fungus, but the disease usually does not develop in a healthy body. Cryptococcal meningitis does not spread from one person to another.

Herpes zoster (Herpes zoster) , also known as shingles, is caused by the same Herpes Varicella-zoster virus as chickenpox. Although this virus also infects HIV-negative people, it is most widespread among HIV-positive people due to a weakened immune system. Virus infection results in extremely painful rashes on the chest, back and face. The rash usually appears in one area of \u200b\u200bthe body and lasts for several weeks. Herpes zoster is treated with antiherpes and pain relievers.

Pneumocystis pneumonia (PCP). The causative agent is the microorganism Pneumocystis carinii, which lives everywhere in the environment. The fungus is believed to be spread by air. The fungus can be present in anyone's lungs, but pneumonia only develops in people with an immune status below 200 cells / ml. Pneumocystis pneumonia, although completely preventable and treatable, is a serious illness that can be fatal if left untreated. Pneumocystis pneumonia can be treated and prevented with a variety of antibiotics, such as cotrimoxazole (Biseptol).

Herpes simplex (HSV) - a disease caused by the Herpes simplex virus. The herpes simplex virus causes sores on the lips ("fever") and eyes, and the virus also causes genital or anal herpes. Herpes sores are more common and more severe in people with HIV than in HIV-negative people. With low immune status, it is a serious problem. The existing antiherpetic drugs relieve and prevent the symptoms of herpes, although they do not completely cure it. If you do not have herpes simplex virus, avoid infections that can occur through sexual contact or through contact with people with active herpes.

Tuberculosis (TB). A dangerous bacterial infection that usually affects the lungs. A person can become infected with tuberculosis from a patient with active tuberculosis by coughing, sneezing or talking. Although HIV-negative people can get TB, the risk is much higher for people with HIV. Although not every HIV-infected person gets TB, TB accelerates the progression of HIV infection and is the leading cause of death among HIV-positive people worldwide. That is why prevention, timely diagnosis and treatment of tuberculosis is very important for HIV-positive people. The presence of mycobacteria is determined using the Mantoux skin test - it should be carried out regularly, at least once a year. If the test is positive (papule more than 5 mm in diameter), isoniazid prophylactic treatment is prescribed. Depending on the severity of the disease, treatment can take several months or even years.

Cytomegalovirus (CMV) can cause in people with low immune status a dangerous eye disease - retinitis - leading to loss of vision. CMV also causes diseases of the gastrointestinal tract, nervous system and other organs. In case of a positive reaction to CMV antibodies and a low immune status, prophylactic treatment (ganciclovir and other drugs) is prescribed. CMV is already present in the body of most people: it is most often sexually transmitted. If you are CMV negative, use condoms or safe sex to protect yourself.

Prevention of opportunistic infections

With HIV infection, it is important to avoid infections that can be dangerous if you have a weakened immune system. However, there is no need to live “under the hood” either.

Talk to your doctor about getting vaccinated against various infections. HIV positive people are not recommended "live vaccines", otherwise they are not contraindicated.

Do not eat raw fish and eggs, uncooked meat or poultry, which may contain harmful bacteria. Raw and ready-to-eat foods must be stored separately and cut on separate cutting boards. Do not store food for too long, do not finish eating something that is "about to go bad." Always wash fruits and vegetables thoroughly, and of course your hands.

It is better to feed dogs and cats with special food rather than raw meat, and do not miss regular visits to the veterinarian. It is better to make cats completely domesticated and not let out on the street. If you have a cat in your home, change the litter box only with gloves. If the immune status is below 200 cells / ml, it is better if someone else does it.

It is important for HIV-positive women to have a gynecological examination regularly (about once every 6 months). Be sure to see your doctor if you have menstrual irregularities, abnormal vaginal discharge, or lower abdominal pain. It is advisable to regularly do a cytological examination of the cervix, it will prevent the development of cancer.

If the immune status is below 100 cells / ml, it is better to drink only bottled or well-boiled water to prevent infections such as cryptosporidiosis.

Contact with people with active tuberculosis should be avoided whenever possible. If you have had a similar risk, consult a doctor, you may need a preventive course of treatment that will prevent the development of tuberculosis.

Finally, do not forget to consult a doctor for serious and dangerous symptoms, which may include various infections: high fever; blood in the stool; prolonged diarrhea; severe chest or abdominal pain; persistent headache; difficulty breathing; deterioration of vision; burning and sores in the mouth. These manifestations may not be associated with any serious diseases, but why take the risk if you can get rid of them?

Based on the article "Fight against opportunistic infections."

Is HPV related to HIV

On July 20, at the 21st International AIDS Conference in Durban, South Africa, UNAIDS, the World Health Organization (WHO) and the Global Coalition on Women and AIDS presented a joint report entitled HPV, HIV and Cervical Cancer: Using Synergistic Mechanisms to Save Women's Lives and compiled as part of the work of the United Nations Joint Inter-Agency Task Force on Noncommunicable Diseases . The report was presented during an informal discussion with representatives from UNAIDS, WHO and the International Community of Women Living with HIV (East and South Africa). Ebony Johnson from Athena was the moderator of the meeting.

HPV has a significant impact on the annual statistics of morbidity and mortality, causing a range of diseases - from benign tumors to invasive cancer. There is also growing evidence that HPV may be an important adjunct to HIV infection.

Given the interrelationships between HPV, HIV and cervical cancer, there is a need to use synergistic mechanisms and take a holistic, problem-focused approach to sexual and reproductive health and saving women's lives.

The release of the report has stimulated lively and informal dialogue for activists, researchers, service providers, development partners and UN representatives. The event was attended by Tessie, Princess of Luxembourg, Yvonne Chaka Chaka and Africa Zulu, Prince of Onkweni.

For citation

“Girls and young women need their rights to be respected and the opportunity to receive comprehensive information and comprehensive health services that fully meet their health needs, including sexual and reproductive health. One effective way of providing such information and services is to enable all girls to receive free secondary education and to introduce high-quality health programs in schools, including HIV, HPV and sexual health services. ”

Mahesh Mahalingham UNAIDS

“All women need to have a general knowledge of HPV and cervical cancer in order to understand their relationship to HIV. Information and access to comprehensive services will help prevent the spread of these AIDS-related diseases among women and girls. ”

Tembi Nakambule director of the National Network of People Living with HIV and AIDS in Swaziland

“If we apply our knowledge of prevention and early diagnosis, cervical cancer will be the easiest of many cancers to detect and treat. However, in low- and middle-income countries, we see a huge gap in the provision of essential services, which leads to high morbidity and mortality from cervical cancer. We must move away from the traditional dividing line between communicable and noncommunicable diseases and develop synergistic mechanisms to save women's lives. ”

Andreas Ulrich division of Noncommunicable Diseases of the World Health Organization

“As a mother of four boys, I tell all the girls in South Africa that I am concerned about the sexual and reproductive health of young people. We know that cervical cancer is killing, but it can be prevented. We must provide help to all who need it and make sure that young people participate in decision-making, because everyone has a place in the world. ”

Yvonne Chuck Chuck singer and activist, South Africa

is HPV HIV-related

Scientists explain the second point today as follows. Use and reprint of printed materials from the woman. The maximum is ARVT with slightly less side effects. Then I'll run to the manager tomorrow. In this case, there seems to be no special need. Therefore, a biopsy is needed. HPV or human papillomavirus is a sexually transmitted infection.

How do men get HPV?

passed (just after the complete rejection of alcohol and nicotine). I have a feeling that HPV and HIV are somehow connected, even Oh girls, after all, I just decided to find out what I have in and whether I have me some Read more from a friend HPV led to cervical dysploses, treatment all together more than r. I read that HPV is present in 90% of people who are sexually active. I myself recently had one papilloma, which itself passed six months later (just after a complete rejection of alcohol and nicotine). I have a feeling that HPV and HIV are somehow connected, even PCR for that and for. Oh girls, I’m just here the other day I decided to find out why I’m in and if I have any infections. In short, I passed the tests at INVITRO. ureaplasma, mycoplasma, chlamydia and HPV all types of which there are-3 pieces. scraping was done, PCR was examined. (ependorof with a transport medium) was not found. Hide. The overwhelming majority of events related to scientific research in the field of HIV / AIDS is the United States and collaborations Could you please tell if HPV can be cured with antibiotics without risking immunity? I am taking therapy. Read moreThe overwhelming majority of events related to scientific research in the field of HIV / AIDS is the United States and collaborations of American scientists. To a much lesser extent, this is the EU. The rest are trace values. Can you please tell me if HPV can be cured with antibiotics without risking immunity? I am taking therapy. Is Hide. Human papillomavirus (HPV) belongs to subgroup A, the papovirus family (Papoviridae). 7 out of 8 studies have shown a link between these infections, a high proportion of HIV infections are associated with any HPV genotype. The human papillomavirus (HPV) belongs to subgroup A, the papovirus family (Papoviridae). HPV is spherical in diameter up to 55 nm. A capsid with a cubic type of symmetry, forms a geometric figure - an icosahedron, built of 72 capsomeres. 7 out of 8 studies have shown a link between these infections, a high proportion of HIV infections are associated with any HPV genotype. Summarizing the studies in women, an increase in the risk of HIV infection in the presence of HPV genotypes was found almost twice, the same association was found in two studies in men. The association between HPV prevalence and increased risk of HIV infection is biologically plausible. Hide.

"Condoms will protect me"

Unfortunately, they do not protect against all STIs. Dr. Rocco explains that they provide some protection, but will not prevent infection from oral sex or skin contact. The virus is most likely - but not always - transmitted through sexual contact. We still do not know what is the duration of the latent period of infection.

It is very difficult to determine, especially for men, when a person has received the virus. This means that men are also exposed to early infection, but may have a longer latency period for infection. How we wish it were! Usually, detailed screening is done only if the results of the cytological test are suspicious. In the case of HPV, things are a little more complicated.

High-risk HPV was recently diagnosed a year ago. They offer treatment regimens, antiviral drugs. Can I take any medications for HIV? Can HPV be cured? High-risk HPV is a type of virus. The risk is determined by specific manifestations, dysplasia and its degree CIN 1.2, It is advisable to find a gynecologist from a high-level medical organization, a specialized center or research institute and be observed with him.

All that can be done is to observe, regular examination, cytological smears, and then, if severe dysplasia has entered, surgery. Early treatment of HIV, in general, is able to prevent the progress of changes in the cervical epithelium and the outcome in severe dsyplasia. That is precisely to treat them with all trades from boredom, as I was told there is no dysplasia and no external changes either.

And therapy scares me wildly, for 4 years the same test rates, the latent course of the disease, as they wrote. The sooner you start therapy, the better for you.

You've already missed 4 years. While replication is in progress, the virus has a destructive effect on your body, increases the risks and they grow over time, even with the intact IP. This shows that the main cause of these processes leading to morbidity and mortality is HIV replication. This is the root of all evil, and the toxicity of ART, compared to the damage caused by HIV replication, is insignificant.

From this you can also see that in order to break the chain with high efficiency, you need to stop replication. The sooner HIV replication stops, the better. Optimally, as soon as it became known that replication takes place. Recommendations for the initiation of HIV therapy in all HIV-infected patients, without exception, who have a detectable VL, are reflected in modern clinical standards. As for Russia, like many third world countries, it cannot afford to treat everyone, therefore in Russia it is necessary " delay ”as much as possible in order to reduce budget expenditures.

Of course, delaying therapy has nothing to do with preserving health, prolonging life and increasing its quality, reducing the incidence and mortality of HIV-infected people.

Bobcat, I am confused by your constant obsequious nods to American commercial health care. And what you call Russia a backward country. It is generally accepted that Soviet and Russian medical science was and is at a very high level.

We have many brilliant specialists and leading research institutes. Doctors from abroad come to learn from the experience. The problem is lack of funding and brain drain.

But with that, every year it gets better. Not everything is so unambiguous in the same USA and even more so in the world with the tactics and methods of HIV treatment. In recent years, it suddenly ceased to be defined. Handed over PCR in different cities. But let's not breed here the cotton-imperial srach. We go with propaganda to Russia 24 and rejoice there.

We are not playing with spillikins here, paroxysms of pseudo-patriotism can have a deplorable effect on health. This is just a given, not a matter of discussion. Whatever you think and whatever you consider, it's just a given. Also not to your taste? Forward and with songs to the orders of the Ministry of Health of the Russian Federation and a couple of domestic magazines. Nobody forces, choose the taste. I personally want to focus on real leaders in medical science, which, by the way, is not directly related to commercial health care, and for myself I see no alternative.

To a much lesser extent, this is the EU. The rest are trace values. However, if tomorrow our scientists will please us with something, we will write for the first time. But this has not happened yet. No matter how pessimistic or optimistic we assess the scientific potential of the Russian Federation today or during the Soviet era, there is nothing in legacy and reality that could be guided by.

In the USSR, then they still attached a small paravoz to azidothymidine, played and abandoned it, but dug it out in the late 90s, unfortunately, they called it Nikavir - that's all the imperceptible contribution of Russian science to the therapy of HIV infection. But this is a delusion. As in the part it is generally recognized, and in the part it was and is at a very high level.

There is no need to cite examples of successes and breakthroughs, for them I have the fingers of one hand and a soreness that rituals over them have been stuffed. I was talking about basic science and medicine in general. All this in x was heavily destroyed and plundered with the help of the same USA and not only medicine. This allows them to advance faster in some areas and have more modern laboratories. Thousands of scientists of the Soviet school who emigrated from the Russian Federation help them in this. And in the field of HIV-AIDS, nothing fundamentally new has yet been created.

The maximum is ARVT with slightly less side effects. Here I missed listening to all this nonsense about the USA and dollars, what it prints, which crawls out of all the cracks. I understand that now there are millions of people who are heavily bitten by telecoms, but STOP. We will not discuss the evil USA and the great Russia rising from its knees here. Everyone remains unconvinced. You don't have to go far. For example, I came and said, I have a patient N. His further treatment will cost our hospital thousands. The first question of the chief medical officer - how long do you think he will live?

I say it's hard to say exactly, maybe a couple of weeks. The nachmed takes a calculator and counts. And this is a good city hospital. Good, let's say, because there are also bad ones. In bad ones, no one will count.

At the same time, formally medical assistance and intensive care measures were provided to you. I here advised someone an insulin pump, for a long time, the woman had poorly controlled glycemia .. Of course, I understood the absurdity of the advice. An ordinary resident of Rostov can spend one-time thousand. There is a salary of 25 thousand. Diagnostics is carried out in the point-of-care format of an ELISA on polymer membranes, which simultaneously detects antibodies and antigens of HIV.

The analyzed sample is a smear with buccal epithelium at the time of admission. The problem of resistance is practically solved due to the high adherence of patients. The institute of patronage social workers, who visit and call the wards, is actively working. Of course, this is to some extent the "Potemkin villages" of Open World, in general, and conceived by the US government to show their country in the best possible light, and its main goal is to attract highly qualified specialists from other countries.

And of course not a word about problems and difficulties, but we don't have that either. I myself have not been to the United States, but I have enough people living there. And this is a typical patient. Does it make sense to vaccinate against HPV for warts on the face, specifically the chin? In the spring, such an attack appeared, removed it with a laser in several steps, missed something, something grew anew.

In this connection, he decided to get tested for HIV in July and he actually showed up, can these rashes also be considered a kind of manifestation of the acute phase? The winter test was -, IS and VN are waiting for the results of the doctors and the laboratory on holidays, so registration is somewhat delayed. Now the manufacturers of Gardasil claim that there is a certain therapeutic effect due to the stimulation of immunity with adjuvant.

But you need to check whether the same strains cause warts in you, which are contained in Gardasil. Usually, dermatological problems are associated with strains 6 and 11. HIV and hepatitis C for more than 10 years, I do not accept therapy. The doctor said to hand over again, and then it will be seen. I'm afraid in a week I will be like in a vegetable garden with cabbage, one head of cabbage almost blocks the vagina, and the doctor does not see Therapy in SC, I'm afraid they will not give it. Then I'll run to the manager tomorrow. I really understand that ARVT could help me, but I'm afraid they will refuse again, I just barely begged for therapy for hepatitis C.

And how is it locally possible to influence it? And another question, will hepatitis C therapy make the situation worse? But if you are right now on the threshold of antiviral treatment for hepatitis C, then according to the observations of some doctors, there is less “cabbage” against the background of HTP. But I'm not sure about the systematic nature of this phenomenon.

And don't be smart about it - it's an art to ask so that they think what they themselves have proposed and thought of. But now it's really not worth adding ARVT. Sorry in advance for the possibly idiotic questions. The CD4 count falls on interferon due to some redistribution of lymphocytes from peripheral blood to lymphoid tissue and due to bone marrow suppression. This happens in the majority, but in some patients, the fall is not observed. Suppressing HIV replication generally makes other chronic infections easier.

Here is something else. This is how it looks: But even if you start, then you had to start before hepatitis treatment, adapt, and only then hepatitis treatment. And now it is more logical to undergo a course of treatment, and only then you can start ART. Your answer is, as always, comprehensive. I will still be treated for hepatitis C with my short course of 24 weeks, oh Thank you very much to all the doctors for the answers! Hello, I have a few questions, I hope for your help.

For earlier, sorry, if not in this section I went with a similar question. And so briefly from the beginning. The gynecologist suggested treatment with Alfareikin 3 million injections into the cervix. I bravely endured this course of therapy, then candles with interferons, a bunch of pills, burning with nitrogen erosion. After half a year, CD and the doctor said that I had hepatitis C. Hepatitis was detected, but upon further tests they said that his immunity had defeated him, he was not.

I was delighted but thank the interferons. So they put me on Eviplera therapy. After 2 weeks, I passed the VN CD tests! In just two weeks of taking medication, such a result !? To date, a month since the beginning of the therapy, it seems to have already adapted, but here out of nowhere appeared genital herpes! How can I treat it if I drink such medicines? Is it not even from petting that petting but contact with the outer labia? I am very worried about my husband that we should run to the center and ask him for HIV prevention?

Or is it possible that herpes was given and HIV is not? Please advise me something. This is about herpes. Growth is probably fluctuations. Given an excellent scheme, the whole world is talking about early treatment, so - just rejoice in any case. Regarding the transmission of HIV - your vaginal secretions, wherever they are on your hands or on your labia, contain enough HIV to infect you. Therefore, if it gets on the mucous membranes of the husband, there is a risk. But if there was contact only with the skin of the labia, on which there was no vaginal secretion, then there is no risk.

It's much easier for herpes. Skin-to-skin contact - and hello! Tell me, if there are no external manifestations of herpes, but it is detected during cytology, that is, it can be in the secretions, is it possible to infect a person if these secretions get on the non-mucous skin? The gynecologist said that there is no such risk. The fact is that you will not notice those very external manifestations. Everyone has one or another herpes virus. One more, one less. If the immunity is adequate, then it will cope and disappear. Can you please tell me if HPV can be cured with antibiotics without risking immunity?

Thank you very much for your answer! Just with the status of the cells, he crawled out every month. And what is conization without histology? Or have you confused cytology smear and histology biopsy? Every doctor has a boss. Again, the patient needs it most of all, not the doctor. Once I heard the phrase “The doctor gets the one who gets it! The last time I was examined by a gynecologist, I passed all tests for infections, including HPV.

There are no infections, no erosion, I have no complaints, there are several warts on the inner side of the thigh. HPV found species if it is important, I will write which ones, I remember exactly 16,18,35, Lymphocytes are increased in the smear. The doctor prescribed the following treatment for me and my husband.

Metronidazole 7 days for both, Doxycycline 5 days for both. Polygynax candles I'm 10 days old. Candles Genferon 10 days for both. Maybe there are more effective treatment regimens? Another doctor prescribed colposcopy after a course of treatment. This treatment and HPV are not compatible. In this case, it is enough to simply remove them, by one method or another. The breasts began to swell, as with menstruation, I went to the gynecologist, passed a bunch of tests, as a result, HPV type 39, uroplasma, I did not give birth to erosion, the doctor said that they did not treat in nulliparous After being treated for uroplasma, the result on HPV was negative, tumor markers are clean, I go to the doctor, I said it is necessary to observe simply for erosion.

Is it really not being treated? I'm 32 years old, maybe all this dysplasia and cannula due to the fact that I have to give birth to a child? Or I have HIV. Dysplasia due to HPV, with a very, very high likelihood, you just determined the wrong thing, not there, or not that.

HPV is a huge amount, and if there were no subtypes with numbers such and such, for which the test was done, then this does not mean that it is not. We wrote about therapy above. You just need to properly treat this case. It's just that I understand that HPV is not treated, it is just that you may not be able to detect it for some period of time. The fact that the tests were clean calmed me a little, because dysplasia, erosion did not disappear anywhere.

You can also find out what tests to pass and what kind of treatment approximately, so that I know what to tell the doctor. And get tested for HIV, probably?

The consequence, manifestations, are treated - erosion, which threatens health, and not the HPV itself. Here's another topic. But I'll write again. Recent analyzes of IP showed hypokeratosis and questionable leukoplakia. Colposcopy of the cervix revealed candidiasis. I was sent for HPV testing and genital herpes.

The analysis of the bacterial pasture came. Moreover, at the time of pregnancy, except for gardnarela, there was nothing and did not live an open sex life.

The doctor wrote a list of drugs and the beginning of the course of treatment, but is afraid of the connection between these drugs and HAART, so as not to cause allergies or something else. An infectious disease specialist is on vacation for a long time.

Can you tell me if you can start taking medication or is it dangerous? Leukocytes U, C-, V Epithelium U, C, V I can't understand where everything came from if the tank. Half a year ago, problems appeared suddenly, sorry for the details, the discharge is abundant, the smell and women's days are smeared very few days.

At least I won't be in the role of an elephant after such a volume? I was shocked by the tests, nowhere with anyone, and here on you. Our calculator has potential interactions of Kaletra and Trichopolum and ofloxacin norfloxacin from the same opera. One course shouldn't be affected. At the beginning of spring, anal warts appeared inside.

For the first time in my life. Outside, there were no manifestations. And nothing bothered. I studied a lot of information on them, tried a lot of traditional and traditional medicine, but everything helped only partially and temporarily.

And so I was about to go to the doctor and remove them the other day and noticed that, lo and behold, everything had disappeared. When I palpate myself, I don’t feel anything at all, everything is smooth, although I previously felt, and when visually examining, as far as possible with a magnifying mirror, there is nothing, although everything was very noticeable earlier. I know they could have disappeared on their own, since almost six months have passed. They say that they can pass by themselves within six months if the body collides with them for the first time.

Probably it happened to me too. I do not lie that my self-medication helped me. How can they be prevented in the future? Felt like a leper with them. Is the vaccine possible or is it too late?

Can smear something for prevention, use candles? I'm not on therapy yet, I'll start by the end of the summer. But you probably don't read my message very carefully. At the moment, the condyloma is gone. They disappeared six months after they appeared.

I would like to know what can be done as a preventive measure to prevent their occurrence in the future. I am not on therapy yet, but I will start it as early as possible. Still, I would like to hear your opinion on preventive measures. I really don't want to face them again. Gardasil vaccination can and will have an effect. But it is impossible to say for sure. Yes, and you need a decent IP to do it and there was at least some sense. Do I need to somehow treat this virus before pregnancy, is it possible at all or the only way to observe the consequences and can this virus affect the unborn child?

Early sexual activity, frequent change of sexual partners, unprotected sex are all factors that increase the percentage of the risk of infection. Secondly, personal hygiene and routine examinations by specialists can reduce the risk of infection, and if it does happen, start timely treatment. Moreover, most types of the virus are treated without any problems - using interferon preparations, various creams and ointments, as well as using cryotherapy and other available means.

In addition, vaccines are available in many countries around the world that produce immunity to the papillomavirus. The most effective are Gardasil and Cervarix. In our republic, if you wish, you can get vaccinated for a relatively small fee, it takes place in three stages at the age of 9 to 45 years. Your e-mail will not be published. Save my name, email and website in this browser for the next time I comment. Any use of materials is allowed only with a direct active hyperlink to Doripenem.

Information on the site about diseases and treatment is advisory in nature.

The article was written based on materials from sites: ru.medic-life.com, aidsinfonet.org, www.medkrug.ru, www.unaids.org, www.jks-k.ru.

A risk factor for contracting viral infections is immunodeficiency, which develops during HIV infection, immunosuppressive therapy after organ transplantation, etc. The causative agents of a number of viral infections are various types of human papillomavirus (HPV). HPV infection occurs through contact (healthy skin - diseased skin). Minor skin injuries contribute to the penetration of infection.

Human papillomavirus (HPV) infections in HIV-infected people.

Epidermodysplasia is verruciform.

Epidermodysplasia verruciform or congenital warts is a viral disease of unknown etiology with a hereditary predisposition. Human papillomaviruses play an important role in the onset of the disease. Elements of the rash are elements that are very similar to flat warts, but they are very large in size, numerous and merge with each other. As a result, large foci are formed, which are very similar to a geographical map.

In places where skin lesions have taken place, linear rashes of elements appear. The development of squamous cell carcinoma, both in situ and invasive, is possible. Usually the rash is located on the skin of the face, hands, arms, legs, and the front of the body. Precancerous diseases and squamous cell carcinoma often affect the skin of the face. Patients with HIV infection are characterized by widespread rashes on the skin of the hands and feet, especially on the face, in the mouth, on the genitals, in the perianal region. Treatment: keratolytics, electrocoagulation, cryodestruction, laser therapy.

Condylomas caused by HPV types 6 and 11, less often - types 16, 18, 31, 33 (the last 4 types also cause squamous cell carcinoma). Infection occurs through contact, including sexual contact, 90-100% of the sexual partners of sick women become infected. In most cases, the infection is asymptomatic and continues throughout the patient's life. The contagiousness of the disease is quite high during periods of exacerbation, when genital warts appear. The incubation period is from several weeks to several years.

The rash is characterized by nodules from 0.1 mm to tumor-like formations that outwardly resemble cauliflower. On the genitals of a man and a woman, the rash is not always visualized; in order to detect it, a test is carried out with 5% acetic acid, after which white small papules appear. Usually, condylomas have a soft consistency, pink or red, in shape they can be warty, filamentous, sessile (on the genitals).

Solitary condylomas are rare, usually numerous and located in groups (resembling cauliflower or bunches of grapes). Perianal genital warts form vegetation the size of an apple or walnut.

Differential diagnosis is carried out with secondary syphilis, molluscum contagiosum, bowenoid papulosis, squamous cell carcinoma, lichen planus, scabies lymphoplasia. During the development of HIV infection, warts spread and large lesions appear that are poorly treated. HPV types 16, 18, 31, 33 are the cause of cervical dysplasia, squamous cell carcinoma of the cervix, bowenoid papulosis, Keir's erythroplasia, etc.

Bowenoid papulosis.

Bowenoid papulosis in its histological characteristics is very similar to Bowen's disease (cancer in situ), but has a benign course. In this disease, the skin and mucous membranes of the genitals, the perianal region, where spots, nodules and plaques appear. In HIV-infected women, it occurs 6-8 times more often than in other women. The causative agent is HPV type 16, 18, 31, 33. The route of infection is sexual. Treatment: cryodestruction, electrocoagulation, laser therapy, fluoride in the form of topical ointment.

Molluscum contagiosum.

Molluscum contagiosum is a viral infection of the epidermis. HIV infection is a risk factor. AIDS patients have a severe course of the disease. Infection occurs upon contact (diseased skin - healthy skin). The primary morphological element is a papule (1-2 mm), in some cases large nodes. Molluscum contagiosum occurs in 20% of HIV-infected people. Typical signs are numerous nodules, nodes with a diameter of more than 1 cm. Location: facial skin, neck, skin folds. In HIV-infected people, relapses are inevitable after removal of the mollusc.

Hairy leukoplakia.

One of the earliest diagnostic signs of AIDS is hairy leukoplakia. This disease occurs exclusively in HIV-infected people and is a poor prognostic sign. If hairy leukoplakia is diagnosed before AIDS is diagnosed, the likelihood of developing AIDS within 16 months is 48%, within 30 months - 83%. Hairy leukoplakia is a benign hyperplasia of the oral mucosa caused by the Epstein-Barr virus.

On the mucous membranes of the cheeks and tongue, whitish or gray plaques with clear boundaries are formed, these elements have villi from a few millimeters to 2-3 cm. The mucous membrane looks like "corrugated paper" or looks like a "shaggy" mucous membrane. This is especially clearly seen on the periphery or on the lateral surfaces of the tongue.

Differential diagnosis: hyperplastic candidiasis, genital warts, geographic tongue (desquamative glossitis), lichen planus, secondary syphilis. Treatment - zidovudine, acyclovir, ganciclovir, foscarnet. Local application of podophyllin (25% solution).