Is it possible to chew Calcemin Advance? Calcemin Advance

Release form

Coated Tablets

Composition

active ingredients:

excipients:

shell

Packaging

In packing of 30, 60 and 120 pieces.

pharmachologic effect

Kalcemin is a mineral and vitamin complex. Fills the deficiency of trace elements, calcium and vitamin D3, helps strengthen bones and joints, prevents diseases of the musculoskeletal system.

Calcium, which is part of the preparation, is a building component for bone tissue, regulates vascular wall permeability, participates in the regulation of conductivity in synapses and neuro-muscular compounds, participates in the contractile activity of skeletal and smooth muscles, is a necessary component for the blood coagulation process. Calcium is represented in the preparation of carbonate and citrate salts. Calcium carbonate contains the maximum amount of elemental calcium. Calcium citrate reduces the dependence of the process of calcium bioavailability on the state of the mucous membrane of the gastrointestinal tract, prevents the formation of stones in the urinary system even in case of prolonged use, reduces the excess production of parathyroid hormone.

Vitamin D (cholecalciferol) promotes adequate absorption of calcium, is involved in the processes of regeneration and the construction of bone tissue.
Zinc is a component of various body enzymes (more than 200 types) that synthesize proteins and nucleic acids. It also provides gene expression, regeneration and cell growth. A positive effect on the activity of the enzyme alkaline phosphatase.
Manganese promotes the synthesis of substances that are components of bone and cartilage tissue (glycosaminoglycans). Potentiates calcium-sparing ability of vitamin D.

Copper is involved in the formation of elastin, collagen. It helps to stop the phenomenon of demineralization of bone structures.
Boron normalizes the activity of parathyroid hormone - parathyroid hormone. The latter is involved in the metabolism of calcium, cholecalciferol, phosphorus, magnesium. The effect on mineral metabolism of parathyroid hormone does not depend on the intake of vitamin D3.

Kalzemin, indications for use

prevention and treatment of osteoporosis,
replenishment of calcium deficiency and trace elements in adolescents;
replenishment of calcium deficiency and trace elements in women during pregnancy and during breastfeeding.

Contraindications

hypersensitivity to the ingredients of Calcemin,
hypercalciuria,
hypercalcemia,
renal stone disease.

Dosage and administration

Calcemin tablets are taken before meals or during meals.

For children over 12 years old and adults - 1 tablet 2 times a day. Children from 5 to 12 years old - 1 tablet 1 time per day. The duration of therapy is determined individually, there is no time limit.

Pregnant with 20th weekand nursing mothers appoint 1 tablet 2 times a day. The drug is prescribed no earlier than 20 weeks of pregnancy.

With calcium deficiency and trace elementsappoint 1 tablet per day.

Use during pregnancy and lactation

During pregnancy and breastfeeding, the drug should be coordinated with the doctor.

In lactating women, it should be borne in mind that colecalciferol and its metabolites pass into breast milk.

Side effects

Seldom: nausea, vomiting, flatulence, hypercalcemia, hypercalciuria, allergic reactions.

special instructions

"Calcemin Advance" - a combined drug that regulates the exchange of phosphorus and calcium. This tool eliminates the deficiency of trace elements, calcium and magnesium, provides the body with vitamin D3. The effect of Calcemin Advance is described by physicians as an action aimed at improving the condition of bones and joints, which can significantly reduce the likelihood of developing diseases affecting the musculoskeletal system.

Composition and release form "Calcemin Advance"

The tool is available in the form of tablets that have a shell. In their packaging can be 30, 60 or 120 pieces. The tablets contain carbonate and sodium borate, vitamin D3. Also in the preparation contains copper and zinc in the form and manganese, having the form of sulfate.

By production of means from excipients use microcrystalline cellulose, croscarmellose sodium. The components of the same action are maltodextrin. Additionally, soy polysaccharide, acacia, stearic acid are used.

The shell is formed from magnesium silicate, hypromellose, mineral oil, triacetin, dyes.

pharmachologic effect

The drug "Kalcemin Advance" instructions for use, reviews are presented as a means that inhibits bone resorption, enhances its density.

The tool successfully fights a lack of vitamin D3 and calcium. It is used for the implementation of the mineralization of teeth. The presence of the necessary amount of calcium provides normal regulation of neuromuscular conduction. This element is involved in the process of blood coagulation, vitamin D3 contributes to its better absorption after the drug enters the intestine. "Kaltsemin Advance", affecting the production of parathyroid hormone, keeps its number normal. In this way, the increase in bone resorption is stopped.

Metabolism occurs in the liver, the metabolites formed as a result of this process are excreted by the kidneys.

Indications for use "Calcemin Advance"

For osteoporosis, Calcemin Advance is taken. Instructions, reviews show that the drug is prescribed both for complex treatment and for the prevention of this disease in the following cases:

menopause (surgical, natural);
long-term use of immunosuppressants, GCS.

The use of vitamins is carried out with the aim of implementing therapy in cases of lesions of the musculoskeletal system, when the main task is to improve the consolidation of fractures resulting from traumatic effects.

Adolescents doctors prescribe this tool, if necessary, to eliminate the deficiency of calcium, trace elements. With the same purpose, tablets are used with increased physical exertion.

Childbearing, lactation

The attending physician decides whether the woman should use Calcemin Advance tablets. Review, left after drug treatment, often reports the need to consider that vitamin D3 and metabolites, which are formed as a result of metabolism, may be present in the composition of breast milk. It is important to pay attention to the quantities in which this vitamin is ingested from other sources.

Kidney problems

Tablets can worsen a condition of patients with a renal failure which is expressed moderately. In such cases, need medical supervision.

Contraindications to receive "Calcemin Advance"

In some cases, patients should not be prescribed Calcemin Advance. Instructions for use, reviews of such cases include:

increased sensitivity to components;
age less than 12 years;
the presence of kidney stones;
urinary excretion of large amounts of calcium;
a pathological condition in which there is an increased calcium content in the blood plasma.

Use of vitamins

The drug is taken orally during the use of food. Patients are prescribed a double dose of the drug in a dosage corresponding to one tablet. The duration of the course of therapy is generally 1-1.5 months. She sets the doctor separately for each case. The maximum dose at a time can not exceed two tablets, the maximum daily dosage should be no more than three tablets. If necessary, the doctor will extend the treatment.

Side effects

After taking Calcemin Advance, a review of a drug may contain some information indicating the possibility of undesirable reactions. Among the possible side effects - the occurrence of allergic reactions, the occurrence of flatulence, vomiting, and the preceding nausea. The presence of hypercalciuria or hypercalcemia may also be detected. Side effects are possible, but they are very rare.

Overdose, in addition to the above manifestations, accompanied by constipation. Irreversible changes in the heart, blood vessels, and kidneys are possible. In case of overdose, the drug is withdrawn, gastric lavage is performed, symptomatic treatment is performed.

special instructions

When used for the treatment of vitamins "Calcemin Advance", reviews recommend taking the drug strictly in the prescribed dose, because the intake of large amounts of calcium in the body can cause disruptions in the absorption processes in the digestive tract of zinc, iron and other important substances.

Since there is some threat to the health of patients with renal insufficiency (expressed moderately), the physician should regularly monitor the level of calcium in the blood plasma and urine.

In order not to overdose due to an excess of vitamin D3, when planning treatment should take into account all the sources from which the substance enters the body.

During pregnancy, a dose of 600 IU (vitamin) and 1500 mg (calcium) must not be exceeded.

Drug interaction

Regarding the drug interaction of Calcemin Advance, the feedback is not always positive. This indicates that the independent combination of drugs is wrong, which means that you need to consult a doctor to determine the possibility of sharing "Calcemin Advance" with other means.

When vitamins are taken together with barbiturates or "Phenytoin", the activity of the complex may be reduced. If sodium fluoride or bisphosphonates are used together, Calcemin Advance may impair their absorption. It is necessary to observe an interval of 2 hours (minimum).

When taken simultaneously with cardiac glycosides, they can enhance their toxic and therapeutic effects. It is important to monitor the clinical condition of patients and regularly make an ECG.

In those cases when calcium-based preparations and tetracyclines are used simultaneously, enhanced absorption of tetracyclines from the gastrointestinal tract is possible. If it is necessary to use both tetracyclines and Calcemin Advance, the recall of the doctors allows for this. However, the funds should be used so that the interval between their receptions was at least three hours.

GCS, laxatives with oils have a bad effect on the absorption of the drug, they slow down the process. Thiazide diuretics used during complex therapy increase the risk of hypercalcemia and increase calcium reabsorption. "Loopback" diuretics contribute to the increased release of calcium into the urine.

Reviews, the price means "Calcemin Advance"

The cost is determined by the number of tablets in the Calcemin Advance package. Price, reviews are of primary importance when buying a drug. For 30 tablets you will have to pay approximately from 235 to 400 rubles, 60 tablets can be purchased for 530-580 rubles. The cost of the drug, the packaging of which includes 120 tablets, is 590-775 rubles.

Judging by the reviews, the drug is often prescribed to strengthen the hair and nails. People who used Calcemin Advance for hair loss, mostly write good reviews. For most of them, the drug helps to cope with this problem.

Means prescribed to saturate the body with minerals. The advantage of the complex is considered an effective combination of macro-and micronutrients, vitamins. But not everyone likes the presence of additional components that can damage the body. Vitamins are useful for bones during menopause, when the body lacks calcium. They are often used during pregnancy to eliminate pain in the joints and back, as well as a source of calcium and vitamin D3. “Calcemin Advance” knowingly has so many positive reviews. The drug copes with all its tasks, side effects are rare. To take "Calcemin Advance", instructions for use, price, reviews are required to study. Taking the pills is possible only after a prescription and in the recommended dose. Then the effect will be maximal, and side effects are unlikely to appear, as they usually are absent in patients.

Name:

Calcemin (Calcemin)

Pharmachologic effect:

Mineral and vitamin complex. Calcium, which is part of the preparation, is a building component for bone tissue, regulates vascular wall permeability, participates in the regulation of conductivity in synapses and neuro-muscular compounds, participates in the contractile activity of skeletal and smooth muscles, is a necessary component for the blood coagulation process. Calcium is represented in the preparation of carbonate and citrate salts. Calcium carbonate contains the maximum amount of elemental calcium. Calcium citrate reduces the dependence of the process of calcium bioavailability on the state of the mucous membrane of the gastrointestinal tract, prevents the formation of stones in the urinary system even in case of prolonged use, reduces the excess production of parathyroid hormone.

Vitamin D (cholecalciferol) promotes adequate absorption of calcium, is involved in the processes of regeneration and the construction of bone tissue.

Zinc is a component of various body enzymes (more than 200 types) that synthesize proteins and nucleic acids. It also provides gene expression, regeneration and cell growth. A positive effect on the activity of the enzyme alkaline phosphatase.

Manganese promotes the synthesis of substances that are components of bone and cartilage tissue (glycosaminoglycans). Potentiates calcium-sparing ability of vitamin D.

Copper is involved in the formation of elastin, collagen. It helps to stop the phenomenon of demineralization of bone structures.

Boron normalizes the activity of parathyroid hormone - parathyroid hormone. The latter is involved in the metabolism of calcium, cholecalciferol, phosphorus, magnesium. The effect on mineral metabolism of parathyroid hormone does not depend on the intake of vitamin D3.

Calcium is absorbed from the gastrointestinal tract, is eliminated from the body with urine, sweat and feces. Calcium absorption is possible due to the activity of calbindin, an enzyme of the intestinal mucosa. Calbindin biosynthesis directly depends on calcitriol, a vitamin D metabolite.

Vitamin D is rapidly absorbed from the intestines. Gets into bones, a liver, adrenal glands, fatty tissue, a cardiac muscle. With the release of vitamin D with bile, its reabsorption is observed. Partially transformed into inactive metabolites.

Zinc is eliminated by the kidneys (10%) and the intestines (90%).

Copper is absorbed from the intestine partially, the rest is eliminated unchanged or in the form of insoluble complexes. 80% of the injected copper is excreted in the bile, 16% in the intestines, 4% in the kidneys, a very small amount in the sweat glands.

Boron after absorption from the intestine is excreted by the kidneys (90%).

Indications for use:

· Prevention of osteoporosis and other diseases of the musculoskeletal system,

· Prevention of diseases of the teeth, periodontal disease,

· Replenishing the deficiency of vitamins and minerals in case of insufficient amount of them in the diet,

· Children - during the period of intensive growth,

· Pregnant and lactating.

Method of application:

For children over 12 years old and adults - 1 tablet 2 p / s. Children from 5 to 12 years old - 1 tablet 1 p / s. Tablets are taken before meals or during meals. The duration of therapy is determined individually, there is no time limit. Pregnant and lactating mothers are prescribed 1 tablet of 2 p / s. The drug is prescribed no earlier than 20 weeks of pregnancy.

Adverse events:

More often observed in case of drug overdose (hypersensitivity reactions to components of calcemin, nausea, flatulence, vomiting, hypercalciuria, hypercalcemia).

Contraindications:

· Hypersensitivity reactions (allergic) to the components of the drug,

· Hypercalciuria,

· Hypercalcemia,

· Kidney disease.

During pregnancy:

Not contraindicated during pregnancy and lactation.

Interaction with other drugs:

Calzemin should not be used with calcium antagonists.

Overdose:

Reports of cases of overdose of calzemin are absent. If the dose has been exceeded, symptomatic treatment is prescribed (gastric lavage, drinking plenty of water, eating foods that are poor in calcium).

Drug release form:

Tablets with elemental calcium content 250 mg, white, capsule-like, notch on one side. The tablets are packed in a plastic bottle. In the bottle of 30, 60, 120 tablets.

Storage conditions:

The shelf life is 3 years, subject to a temperature of 25-30 ° C. Keep away from light. Keep out of reach of children.

Composition:

Active substances: calcium citrate 842 mg, calcium carbonate 202 mg, cholecalciferol 50 IU, copper 0.5 mg, zinc 2 mg, boron 50 μg, manganese, 5 mg.

The inactive ingredients: microcrystalline cellulose, magnesium stearate, acacia, sodium lauryl sulfate, croscarmellose sodium, starch, cotton seed oil, calcium phosphate, gluten, sodium citrate, stearic acid, hydroxypropyl cellulose, maltodextrin, sugar, hydroxypropylmethylcellulose, titanium dioxide, gelatin, tocopherol, polyethylene glycol.

Additionally:

At the age of 5 years it is possible to use the drug only under strict indications. The drug for children of this age should be taken only under the supervision of a physician.

Preparations of a similar effect:

Immunovit (Imunovit) Quertin (Quertin) Ascotsin (Ascozin) Retinol acetate (Retinol acetat) Volvit (Wolvit)

Dear doctors!

If you have experience of prescribing this drug to your patients - share the result (leave a comment)! Did this medication help the patient, did any side effects occur during treatment? Your experience will be of interest to both your colleagues and patients.

Dear patients!

If you have been prescribed this medication and have been on a course of therapy, tell us if it was effective (did it help), were there any side effects that you liked / did not like. Thousands of people are searching the Internet for reviews of various drugs. But only a few left them. If you personally do not leave a review on this topic - there will be nothing to read the rest.

Thank you very much!

During pregnancy, a woman needs additional intake of calcium and minerals to form the fetal skeletal system. Therefore, doctors prescribe the future mother appropriate diet and calcium-containing drugs. Calcemin during pregnancy provides prevention of osteoporosis in the mother and the normal development of the unborn child.

Like any drug, it has features of use. Consider the contraindications and indications for taking Calcemin, its analogues and composition.

Calcemin is a complex preparation containing a balanced amount of minerals and vitamins. Its name indicates that the main active ingredient is calcium. Extremely important is the presence in the composition of Calcemin vitamin D3, which ensures the absorption of calcium by the body.

Each of the components of the drug performs important functions in our body. Calcium is involved in the following processes:

formation of bone structure and cartilage;
providing contractile function of muscles, bone strength;
strengthening the walls of blood vessels;
increase the elasticity and strength of the tendon-ligament apparatus of the joints, the spine;
regulation of blood clotting;
preservation of acid-base homeostasis.

In addition to calcium, the preparation contains several other chemical elements. Each of them deserves separate consideration.

Zinc is part of the bone tissue, cartilage and tendons, performs a number of functions:

provides the growth of bones and ligaments;
promotes the regeneration of bones and joints when damaged;
participates in protein metabolism;
is a structural component of a number of enzymes and hormones.

Manganese is important for its participation in building bone-ligamentous structures, making muscle contractions. It is also necessary for biochemical and enzymatic reactions.

Copper is part of collagen, elastin. These proteins form the basis of ligaments, tendons, cartilage. This chemical element is needed for normal metabolism, hematopoietic activity of the bone marrow, the functioning of the most important organs.

Boron improves calcium phosphorus metabolism indirectly by acting on the parathyroid glands. It stops the leaching of calcium from bone structures and the development of osteoporosis during pregnancy. In addition, boron prevents the accumulation of calcium in the internal organs, the walls of blood vessels, increases the activity of vitamin D.

Cholecalciferol (vitamin D3) also provides important processes:

regulation of calcium and phosphorus metabolism;
absorption of minerals from the intestines;
effective incorporation of calcium in bone structures;
acceleration of the regeneration processes of damaged or overworked muscles, tendons, bones, their strengthening.

Indications and contraindications

Calcemin is used for prophylactic and therapeutic purposes. Indications for appointment to pregnant women and young mothers - prevention and treatment of osteoporosis, elimination of symptoms of calcium deficiency.

Contraindications to receive Calcemin:

gestation period is less than 20 weeks;
chronic renal failure;
the presence of stones in the urinary system;
individual intolerance to the components;
increased concentration of ionized calcium in the biochemical analysis of blood in the urine;
excess blood cholecalciferol.

Can I use the drug during pregnancy?

A lack of calcium leads to many negative consequences, especially for the future mother's body. There is a fragility of bones, caries, hair falls out. Women with calcium deficiency are more likely to go to doctors because of early toxicosis, they are concerned about pain in the joints, nightly. Often there are hypertensive crises, pain in the heart.

Therefore, during pregnancy, calcium supplementation, enriched with minerals and vitamins, is very important. Otherwise, a woman may develop osteoporosis, and the future baby - a violation of the formation of the skeleton, a number of organs and systems.

But excessive intake of any, even beneficial substance, in the period of gestation can be harmful. Therefore, choosing calcium-D3-containing drugs, one should be guided by physiological norms of consumption: the daily dose of calcium should not be more than 1.5 grams, cholecalciferol - 600 mg. The dosage, the multiplicity of reception, the duration of the course should be coordinated with the attending doctor.

Calcemine administration is usually recommended. It is at this time begins the active formation of the skeletal system of the child. For bone fractures and signs of calcium deficiency, the drug may be prescribed at the initial stages of gestation.

Calcemin or Calcemin Advance?

These preparations are produced by one company, the components of the vitamin-mineral complex are the same. The differences relate only to the content of active ingredients. Calcemin Advance contains them in higher doses. Therefore, Calcemin is used prophylactically to normalize calcium metabolism in pregnant women.

Kalzemin Advance is a therapeutic drug prescribed in the following cases:

injuries of the musculoskeletal system, fractures;
age-related osteoporosis;
the need for long-term use of corticosteroid hormones, anticancer drugs, immunosuppressants and other drugs that cause increased bone fragility.

Calcemin Advance is prescribed for pregnant women only under strict indications.

Content of ingredients	Calcemin	Kalzemin Advance
Calcium citrate	840 mg	217 mg
Calcium carbonate	200 mg	1312 mg
Vitamin D3	50 IU	200 IU
Manganese	5 mg	1.8 mg
Zinc	2 mg	7.5 mg
Copper	0.5 mg	1 mg
Boron	50 mcg	250 mcg

How to take Calcemin?

With the preventive purpose of the drug is used within a month, 1 tablet before meals or during meals 2 times a day. It is usually prescribed from the 20th week.

After 35 weeks of pregnancy, Calcemin cannot be taken, as this leads to an accelerated ossification of the fetal skull, complicating the process of childbirth. When a gross violation of mineral metabolism, gynecologists prescribe the drug already in early pregnancy.

It is important to drink Calcemin with enough liquid or dairy products, this improves calcium absorption, increases the effectiveness of the drug.

The instructions also indicate a number of undesirable effects of taking the drug. The following adverse reactions are most common: allergies (itchy skin, urticaria), disorders of the digestive system - abdominal pain, nausea, unstable stool. If any discomfort appears, stop taking it and consult a doctor for a replacement.

Analogs

For the treatment and prevention of calcium deficiency during pregnancy, many drugs have been synthesized. The following remedies are most popular:

Compl Calcium D3. It normalizes mineral metabolism, is administered 1 tablet per day during the month.
Calcium + Vitamin C. It is recommended when carrying a fetus and during lactation, with overload, asthenic conditions. The duration of treatment is determined by the doctor.
Citra Calcemin. It is widely used during pregnancy, the main active ingredient of the drug is calcium citrate.
Calcium-D3 Nycomed. Contains calcium and vitamin D3. Trace elements that are part of Calcemin, in this preparation are absent, which is its disadvantage.
Vitrum Osteomag. Complex drug, which contains vitamin D, calcium, magnesium, copper, manganese, zinc, boron.

Calcemin during pregnancy is effective for eliminating calcium deficiency in the body and improving mineral metabolism. It is an optimally balanced vitamin-mineral complex, rarely causing undesirable effects.

Taking Calcemin, expectant mothers note a normalization of well-being: toxemia disappears, mood improves. But self-medication is unacceptable. Only a doctor can determine the required duration of treatment and select the drug based on individual characteristics.

Useful video: why calcium is so important for pregnant women?

I like!

Registration number

Tradename: Calcemin

Dosage Form:

coated tablets.

Composition:

Active ingredients:

Calcium 250 mg (calcium citrate and calcium carbonate), Vitamin D3 (cholecalciferol) 50 ME, copper (copper oxide) 0.5 mg, zinc (zinc oxide) 2 mg, manganese (manganese sulfate) 0.5 mg, boron (sodium borate) 50 mcg.

Inactive Ingredients:

Maltodextrin, microcrystalline cellulose, croscalous sodium, acacia, stearic acid, soy polysaccharide, magnesium stearate.

Shell:

Hydroxypropyl methylcellulose (hypromellose), magnesium silicate, titanium dioxide, sodium lauryl sulfate, silicon dioxide, polyethylene glycol, mineral oil.

Description:

Tablets are elongated capsule-shaped, coated white, with a notch squeezed out on one side. Pharmacotherapeutic group: Calcium-phosphorus metabolism regulator. ATX code: A12AX.

Pharmacological properties:

The combined preparation containing vitamin DZ, micro and macrocells. It regulates calcium and phosphorus metabolism, compensates for the relative deficiency of trace elements and vitamin DZ, prevents diseases of the musculoskeletal system, and strengthens the skeletal system and joints.

Indications for use.

Prevention and complex treatment of osteoporosis of various origins:
To compensate for calcium deficiency and trace elements in adolescents, in women during pregnancy and breastfeeding.

Contraindications.

Increased individual sensitivity to any of the components of the drug, urolithiasis, hypercalcemia and hypercalciuria.

Dosage and administration.

Adults and children after 12 years, one tablet 2 times a day with meals. During the period of pregnancy and breastfeeding from the 20th week of pregnancy and the entire period of breastfeeding, 1 tablet 2 times a day. For children from 5 to 12 years old, use 1 tablet 1 time per day with meals. With a deficiency of calcium and trace elements, the recommended dose is 1 tablet per day.

Side effect

In rare cases: nausea, vomiting, flatulence, hypercalcemia and hypercalciuria, allergic reactions.

Overdose

Overdose may cause constipation, nausea, and vomiting. Overdose manifestations also include hypercalcemia and hypercalciuria, leading to an accumulation of calcium in soft tissues and irreversible changes in the kidneys and cardiovascular system.

special instructions

The dose should not exceed that specified in the instructions, since increased calcium intake may inhibit the absorption in the intestines of iron, zinc and other essential minerals.

Use during pregnancy and breastfeeding

During pregnancy and breastfeeding, the drug should be coordinated with the doctor.

In lactating women, it should be borne in mind that cholecalciferol and its metabolites pass into breast milk.

Release form

Tablets, coated.

On 30, 60 or 120 tablets in a bottle from polyethylene of high density with the screwing-up cover from polypropylene sealed by a film. Each bottle together with the instructions for medical use is placed in a cardboard box.

Storage conditions

In a dry place inaccessible to children, at a temperature of 15 - 30 ° C.

Shelf life

3 years. Do not use after the expiration date printed on the package.

Pharmacy holidays

Over the counter.

Manufacturer Sagmel Inc., Chicago, USA Sagmel Inc., 1580 South Milwic Avenue, 218, Libertill. Illinois, 60048, USA.