Appointment Clotrimazole. The main indications, storage and possible negative effects of clotrimazole exposure. Warehouse and release form
Clotrimazole ointment can be called a universal drug for fungal infections.
Yogo a wide range of activities allows you to infuse on various types of fungal pathogens, including silently, yaki attack the scalp and genital area. This drug has been produced for a long time on the pharmaceutical market, it can be produced by various pharmacies and foreign medicines, if it is available, it can be produced with a lot of structural analogs, it can be mixed with other pharmaceutical preparations.
On this side you will find all the information about Clotrimazole: the same instructions for how to get to the right drug, the average price in pharmacies, the same and different analogues of the drug, and also the opinions of people who have already taken Clotrimazole ointment. Would you like to deprive yourself of your thoughts? Be kind, write in the comments.
Clinical and pharmacological group
Antifungal drug for ovarian congestion.
Wash your permits from pharmacies
Available without a prescription.
Prices
What are the prices for Clotrimazole ointment? The average price in pharmacies is 47 rubles.
Release form and warehouse
Clotrimazole ointment may be white or may be white color, uniform structure and solid consistency. Basic fluffy speech the drug - clotrimazole, yoga in 1 g of the ointment becomes 10 mg.
Additional components of the ointment:
- Methyl parahydroxybenzoate.
- Polyethylene oxide 1500.
- propylene glycol.
- Methylparaben.
It is available in aluminum tubes in a quantity of 30 g.
Pharmacological effect
Clotrimazole is a drug with a pronounced antifungal power, which can be compared to similar imidazole. The vicarious drug allows the synthesis of ergosterol, thereby disrupting the penetration of clitin fungi, leading to their death. Clotrimazole is an active component of an ointment effective for dermatophytes, yeast, mold fungi, may have an antibacterial effect in staphylococcal, streptococcal infections. Vykoristovuvat tsey drug can be in case of various diseases of a fungal nature.
Once applied to the skin, the active component is wetted gently at the upper and deep layers of the epidermis, practically does not penetrate the bloodstream. The fact that after a victorious therapeutic effect will be remembered not in a moment, but in good time is important to the preparation. However, with a trivial exposure, the effect of the drug will be 100%. It is even more important in the process of using the ointment to trim the hygiene of the shkir, and also not to miss the stagnation.
This ointment does not only allow fungal infections, but it also reduces infection of the skin with other bacteria, which often aggravates the process of healing and overcoming illness.
Indication before zastosuvannya
What do you help? Clotrimazole ointment can have an antifungal effect, but it’s not only good to drive in a fungus - speech, which is actively active, harmfully affects other pathogenic microorganisms, as a negative effect on the burning camp of healthy people.
Indications before acceptance of ointment Clotrimazole є:
- paronychia;
- lost infection candidiasis + trichomoniasis;
- dermatophytosis and other fungal infections.
Quite often this ointment is prescribed for lubrication - fungi, which call out to be ill, even more sensitive to the main fluent speech, and to that, it is notable to be low. Medicines are aware of depression, if Clotrimazole ointment helped to relieve pronounced pigmentation, regardless of those that are exclusively antifungal.
Poorly copes with the analysis of the drug i h, i h.
Contraindication
Allergic reactions or hypersensitivity to fluffy speech to the drug or other components, menstrual period (with vaginal congestion).
Children are allowed in 2 years.
Installation instructions
In the instructions for the application, it is stated that the Clotrimazole Ointment for normal zastosuvannya should be applied to the clean lesions of the tree with a thin ball of sprat once a day, gently rubbing. Trivality of likuvannya to lie down in the form of localization, severity of illness and effectiveness of therapy:
- Dermatomycosis rejoice for at least a month;
- Visіvkopodіbny lichen - up to three types;
- Fungal infection of the shkir nig - therapy is continued for at least two days after the symptoms have passed.
For treatment of ailments, you can also vicorate Clotrimazole cream.
After applying the Clotrimazole ointment, it was not necessary to apply a hermetic bandage.
Side effects
With severe congestion of the ointment, Clotrimazole can cause swelling, as well as the liver, desquamation or teasing of the skin, sverbіzh, erythematous hanging, paresthesia, swelling or kropivyanka.
Overdose
To date, no overdose of clotrimazole ointment has been registered.
especially vkazіvki
- It is not recommended to apply the drug on the skin in the eyes.
- At the time of the appearance of the effect, the diagnosis was confirmed within 3 days.
- With the appearance of a sign of hypersensitivity, they pinch the roaring glee.
- In patients with hepatic insufficiency, it is necessary to periodically control the functional state of the liver.
Medical interaction
Amphotericin, nystatin, natamycin reduce the effectiveness of clotrimazole with one-hour ingestion.
In case of ointment congestion, negative interactions should be taken with other methods, it is not necessary to clean them up, because the resorption capacity of clotrimazole is even low.
Suggestions
We picked up the deacons of people, like victorious ointment Clotrimazole:
- Natalka. I already have over 20 roki on shiї periodically (4 months - pіv roku) are plyami, similar to a fungus. I consulted with a doctor, she prescribed Exifin ointment for me. I will pass the course of likuvannya - everything is over. After 4 months -5 they appear again. I smear again. And then she told me about her problem in the pharmacy, I was struck by a fungus that killed me in the middle by popping a Flucanazole capsule. I sipped it, after three months I sipped another ode, singsongly. And nothing has passed! Well, why don't you sit with me, why don't you fight anything? Axis want skushtuvati ointment Clotrimazole. A bit of ointment is not bad. I support you, help me!
- Katia. Clotrimazole exulted the nail fungus. Pіdhopila pіd vаgіtnostі hour. Periodically rubbed the ointment on the nails and sheared the damaged vine. I smeared it with a tanner 10 times.
- Zoya. I even wondered if on the third day my fingers became as good as new, but it was easier to walk through. people's well-being I tried it and it became only slightly worse. The growths became like rough zhovti, and even worse the stench began to crackle and to the point of blood it became more painful to step on the foot. I turned to the Internet and read about the drug CLOTRIMAZOLE ointment, more or less, it came up with a wide range of wines and even wondered about the cost of 30 rubles. After all, I believed in medicine and went to the liquor to clarify the diagnosis and correct it to the end. Obviously, I didn’t go down from the gir, and medicine used to bring me to life more than once, but I think there are small inaccuracies at the sight of small cracks on the foot of the price of the nurse, for example, it wasn’t there that the fungus was there. don't spend an hour on vipadkovі for the sake of the stink of all the garni only for prevention, but as soon as the fungus comes up to the doctor. Good for me on the eyes having consumed the drug and meni wine dopomig.
- Margarita. I suffered for a long time with ringworm, I tried everything can you please folk medicine(God's sweet, soda, iodine, herbs) and expensive faces. The drug is on a likuvannya acknowledging even cheaper cream Clotrimazole. She was even more excited - after the first day of stagnation, the skin began to smooth out, and after three days everything was gone.
Analogues
What are the analogues of Clotrimazole ointment? Well. They can be divided into two groups: with identical fluent speech and with others. Lie down to the first group:
- Amiklon;
- Candid;
- Candide - B;
- Candibene;
- Kanesten;
- Kanizon;
- Imidil.
Yak i Clotrimazole, relisted drugs and may be in other forms of release, cream cream.
To another group, you can add the following ointments:
- Pimafucin (intoxicating component of natamycin);
- Lamisil (terbinafine);
- Terbisil (terbinafine);
- Fungoterbine (terbinafin);
- Fucis (fluconazole) and other analogues.
Before using analogues, consult a doctor.
Wash away the savings and the term of appurtenance
The term of applicability to ointment Clotrimazole becomes 2 rocks from the moment of preparation.
The drug must be stored in a place inaccessible to children at a temperature not higher than +20 º C. The ointment must not be frozen.
May the skin of a person stick with such a problem, like a thrush. Vaughn blames raptovo, nibi nіzvіdki and bring a lot of inaccuracies, zavdayuchi bad health. Clotrimazole will help you get rid of this disease.
What is thrush
What is a thrush? Tse fungal infection, Viklikane especially mentally pathogenic microorganism Candida, which lingers in the healthy microflora of the mucus person. The ailment begins just as soon as the colony of yeast-like fungi begins to grow sharply.
Such a phenomenon is revealed to the body from the destruction of the powers of the past. Often through tivala ailments, on aphids tivalo to the reception of antibiotics and/or hormonal preparations or else blame the trivial perebuvannya people in extreme stressful situations. Vplinuty on viniknenny thrush (in other words - vaginal candidiasis) can:
- chronic illness;
- ailments exchange of speeches;
- allergy;
- vaginess;
- underestimation of special hygiene;
- zhorstki diet;
- immunodeficiency;
- oncology;
- more often than not, zastosuvannya tampons;
- wearing a synthetic lower white that swears;
- chemotherapy course.
As a result, the natural balance is disrupted, and the Candida fungus begins to grow, mucus membranes and skin curls.
A thrush does not care about unsafe illnesses, but for the presence of a sizable exultation, it can show itself as a catalyst to endure serious health problems.
About thrush (candidiasis): video
Efficiency of clotrimazole in the fight against thrush
Vaginal candidiasis will require complex treatment: mіstsevoy and vnutrіshny. The most frequently therapeutic activities will help to overcome serious complications.
Often in the thrush of women, children and children, there is such a universal zasib zovnishnoї dії, like Clotrimazole. It is a simple, ale deviy drug, effective in therapy not only for candidiasis, but also for driving a number of disease-causing microbes, such as staphylococci, streptococci. Vіn usuvaє symptoms that accompany illness:
- white syrian pour;
- swelling;
- soreness;
- hyperemia.
Shvidkogo result not varto chekat, prote, dorimuyuchis clear words of the doctor, you can reach full exaltation. With this drug, the potency is low. And to increase the number of forms of Clotrimazole, allow to speed up the dressing.
The effectiveness of the drug is based on the action of the active language on ergosterol, which enters the warehouse of fungal membranes. Tse zmushu spend their lives of speech, which lead to death. Clotrimazole is injected into these micro-organisms, as they grow along the way. Vіn ruynuє kіtini and superechki candida, paralyzing their life.
Minimum doses, irregular doses are less likely to block the expansion of the range of thrush. Externally, the blame of the health worker is only possible with a complex approach, high doses, and other doctor's recommendations.
Warehouse and form release
Clotrimazole is considered to be antifungal and synthetic antibacterial agents. The active ingredient is 1-[(2-chlorophenyl)diphenylmethyl]-1H-imidazole (C22H17ClN2). This is a crystal speech of a white color, which does not smell, it is indistinct near the water.
The drug Clotrimazole is marketed by various pharmaceutical companies around the world. Іsnuє kіlka forms of thsgo likarskogo zasobu:
- vaginal candles;
- vaginal nipple;
- cream;
- rozchin;
- gel.
All tsі see Clotrimazole vicorista zvn_shno or intravaginally (for women).
Forms of Clotrimazole and its additive components
Oskіlki є wide variety of forms of release, those warehouses (additional components) are different.
Cream
Cream Clotrimazole 1 and 2% is effective in treating thrush in men and women. Yogo benefits:
The warehouse cream has the following additional components:
- rare paraffin;
- ketosteril alcohol;
- white soft paraffin;
- ketomacrogol 1000;
- the water is purified;
- chlorocresol;
- disodium goes;
- citric acid;
- dibasic sodium phosphate (anhydrous);
- propylene glycol;
- sodium metabisulfite.
Vaginal candles
The most widened form of application for the treatment of thrush in women is vaginal suppositories (candles). Features of this type of clotrimazole:
In warehouses of vaginal suppositories, cream of active speech, presence of synthetic glycerides (solid fats).
Gel for healthy zastosuvannya
Gel is a new form of clotrimazole. This is the same substance of the white color of the mass zastosuvannya. Such a zasіb quickly climbs, troch podsushyuyuchi urazhenі mіstsya.
At the warehouse gel:
- cetyl alcohol;
- propylene glycol;
- glycerol;
- benzyl alcohol;
- cetomacrogolium emulsion whisk;
- carbomir 940;
- sodium hydroxide;
- chlorocresol;
- water is purified.
Rare form of clotrimazole: rozchin
Rozchin notably recently appeared on the pharmaceutical market, moreover, he did not get a wide zastosuvannya in the juicy thrush. Tse prozora, trohi v'yazka rіdina іz alcoholic smell.
At the warehouse, there is a need for looking at the additive components present:
- benzyl alcohol;
- propylene glycol;
- 2-octyldodecanol;
- polyethylene glycol 400;
- sodium citrate;
- isopropyl alcohol;
- water.
Ointment Clotrimazole-Akrikhin
The most common ointment for the treatment of thrush is the ointment. The most popular is Clotrimazole-Akrikhin from the Russian virobnik. This is an inexpensive zasіb in line preparations of the same kind. The ointment shvidko envelops the mucous membrane, soothing the dry areas. Efficiency її - close to 90%.
Additional components of the ointment:
- propylene glycol;
- polyethylene oxide 1500;
- polyethylene oxide 400;
- nipagin (methyl parahydroxybenzoate).
Vaginal puffs
During the rest of the hour, doctors often recommend taking Clotrimazole in tablets for intravaginal ingestion. Їhnya perevaga - vіdsutnіst greasy basis. However, the variety of vaginal tablets is similar to other pharmaceutical forms of Clotrimazole.
Additive components of vaginal tablets є:
- lactose monohydrate;
- potato starch;
- adipic acid;
- sodium bicarbonate;
- magnesium stearate;
- silicon dioxide coloid;
- sodium lauryl sulfate.
Many packages with such faces have a special applicator for introducing the drug deeply into the drug.
Spray
Gaining popularity spray Clotrimazole. Enough 1-2 hardships to cover the entire outer surface of the state bodies. Often yogi vikoristovuyut cholov_ki at the lіkuvannі thrush.
Yogo has a warehouse of active speech:
- isopropyl myristate;
- ethyl alcohol.
Obmezhennia and contraindications: what can be cured with vagity
Like all medicinal preparations, clotrimazole has a low side effect and is contraindicated to the point of congestion.
Contraindication
Usі form the release of Clotrimazole can not vikoristovuvat in such vipadki:
Exchange
It is necessary for the protection of vicorists to zasib:
- pid hour of vacancy for the 2nd and 3rd trimesters;
- in the period of lactation;
- for the presence of chronic liver failure;
- yakscho of a patient for over 60 years;
- on the background of pathology of hematopoietic organs;
- under the hour of colds, ill, which are accompanied by fever and elevated body temperature.
Side reactions
Zvuchay Clotrimazole is easily tolerated by patients, without serious adverse reactions. It is believed that if the recommended doses are exceeded, a negative reaction to the body is blamed.
You can watch out:
- chervoninnya mucus;
- you can see the liver and the pokolyuvannya at the places of application;
- kropivyanka;
- razdratuvannya;
- nudota, what to go over at the vomit;
- the appearance of indigestion;
- cystitis;
- peeling skinny curves;
- speed up the cutting;
- bіl pіd hour of the statutory act;
- head bіl;
- seen from state bodies.
Special mind
Іsnuyut especially mind, if it is not necessary to use Clotrimazole:
- zastosuvannya deyakih drugs: Nistatin and Natamycin;
- stagnation of other vaginal diseases;
- the introduction of alcoholic products;
- not stealing sex.
The drug preparation Clotrimazole and all its structural analogues, including Clotrimazole-Acriquine, are non-prescription drugs. However, this does not mean that you can splurge on self-admiration. Only a doctor after diagnosing a thrush can prescribe the zasib. The course of therapy does not exceed 4 days and stay in doses of these drugs. Regularity - not less than 2 times per harvest.
As if after the first day of the week, the victors did not fear polypsy, they turned to the doctor for the change of the doctor's order.
How to stop women
Vykoristovuvat cream, ointment, suppositories and vaginal tablets Clotrimazole for women can be an offensive rank:
- Lying on your back, bending your legs in knees and placing them at the side, it is necessary to introduce a large coal of pikhvi.
- If it is a special applicator, then this manipulation can be done with help.
- After the introduction of the drug, the trochs should lie down (no less than 30 quills).
- So that the faces do not flood the patches on the back, it is recommended to use good pads, but otherwise not tampons.
- When vikoristanni tablets їх require further soaking in warm water.
Often, the drug is prescribed for the treatment of thrush at the same time as a sprat of the drug. In times it is necessary to improve the consistency of the skin form. Ointment and / or candles dotsilno vikoristovuvat before going to bed, and cream, gel, pills - at early that day.
How to curry favor with people
Naturally, in the treatment of thrush, people vicorist have such forms of Clotrimazole, like an ointment, cream and rosin. With the method of preventing the recurrence of the lust of both partners, the obov'yazkovim.
An unhealthy disease can become a reason for the development of unsafe pathologies, such as vesiculitis and prostatitis.
Irrespective of those who thrush is into women's ailments, candida fungi, with reduced immunity, take root on human genitalia. That is why, when a partner has a thrush, she needs obov'yazkove likuvannya. As a rule, a urologist prescribes Clotrimazole for doba to people. With tsioma ointment, rozchin chi cream is applied to a clean glans penis.
Vikoristannya with the method of prevention
Clotrimazole does not zastosovuєtsya as a prophylactic zasіb for strangulation of a possible fungal infection, but every hour it is victorious for the sanitation of ancestral paths in advance of the birth of a child.
Analogues of Clotrimazole in the treatment of thrush
For some reason, it is not possible to vicorate likarsky zasib, then the doctor has the right to replace the drug with an analogue, so as not to take clotrimazole in his warehouse.
Analogues of the drug - table
| Naming the drug | Form release | fluffy speech | Indication before zastosuvannya | Contraindication | Side effects | Vikoristannya with vagity | The average variety and virobniki |
| bifonazole | Candidiasis:
|
| allergic reactions | with care |
Virobnik Synthesis VAT (Russia) |
|
| omoconazole |
|
|
Virobnik Teva Pharmaceutical Works Co. Ltd. (Ugryshchyna) |
|||
| Pimafucin |
| natamycin |
|
| allowed |
Virobniki:
|
|
| Neo-Penotran | vaginal suppositories |
|
| average price - 900 UAH. Virobnik Embil Pharmaceutical Co. (Turechchina) |
|||
| Nistatin |
| nystatin | infection caused by fungi, including candidiasis of various etiologies. |
 Bifosin is rarely vicorous in treating vaginal candidiasis. |
Pharmaceutical drug Clotrimazole cream is used for pathologies caused by a fungus, for example, vaginal candidiasis or thrush. The main active speech is responsible for destroying the membranes of fungi and causing harmful influx on pathogenic microorganisms. Zavdyaki low price positive feedback, this drug against fungus is one of the leaders in the pharmacological market.
What is Clotrimazole Cream
In case of fungal infections, skins, nails, vaginal candidiasis (thrush) are prescribed medical therapy antibacterial ointment Clotrimazole (clotrimazole). The drug may have a strong antifungal effect on the cause of erythrasma, fungal psoriasis and other advanced mycotic diseases. You can prescribe the ointment likar for the first symptoms of infection, for the prevention of mycosis in the balls of the skin and on the mucous membrane of the skin.
Lіkarskiy zasіb prignіchuє rіst, rozvitok podіl fungal kіtin. In addition, the drug is widely used in case of infections of the ducts (for example, in case of vaginal mycosis of the tunic of the pylorus). For treatment of candidiasis, the ointment is prescribed to both partners. In this case, it is recommended to apply a cream before the act, so immediately after that.
The drug is in the form of a cream with a light yellow color, a consistency of fatty sour cream, packed in an aluminum tube and a cardboard package with annotation to the letter, instructions for injecting the antifungal drug. Clorimazole ointment is available for sale in pharmacies and online stores without a doctor's prescription.
warehouse
The drug is released from kіlkoh medicinal forms ah: vaginal pins, candles, ointment, cream for ovarian congestion. Remaining May Coming Warehouse:
- The main active ingredient is clotrimazole 10 mg.
- Additive speech - ethyl alcohol, vaseline, glycerol, distilled water, solid fat.
Pharmacological activity
The drug disrupts the synthesis of ergosterol, which enters the warehouse of the membrane of clitin fungi. Clotrimazole suppresses the processes under the clitin of pathogenic microorganisms and belongs to one of the most effective antifungal agents, but it can have a wide range of effects. The drug is harmful against both Gram-positive and Gram-negative bacteria. Doctors recommend starting therapy for the first sign of infection.
New Clotrimazole
Cream with clotrimazole may be indicated before congestion:
- fungal diseases of skin coverings;
- mycosis of feet, dolon, skin folds;
- lichen lichen;
- thrush;
- erythrasma;
- superficial and deep candidiasis.
Instructions for application Clotrimazole cream
Faces Clotrimazole zastosovuyut for good application in antifungal therapy. The medication, according to the instructions, is applied with a thin ball 2-3 times on the doba. on a clean and dry litter of shkir with damaged epidermis. In order to achieve the best effect, it is recommended to apply compresses with a stretching cream for a few days, so that the faces get wet at high concentrations. The validity of the course of therapy depends on the severity of the disease, localization of pathology, efficiency.
For women
A drug with antifungal activity Clotrimazole is used for women who suffer from frequent thrush infections, vaginal infections and other bacterial infections. Trivality to the course of healing becomes 5 to 10 days, fallow due to the severity of illness. Clorimazole is recommended to be taken for prevention of candidiasis in the period of catarrhal infections and lowering of the immune system. For the protection of the next zastosovuvaty drug preparation pіd hour of menstruation.
For people
Cream with clotrimazole for people zastosovuєtsya is important for the treatment of chronic and acute forms of candidal infections of the genitals. Treatment of fungal ailments in people occurs in 4 to 7 days. It’s better to start with a cream, if the first signs of ailment appeared: strong sverbіzh, liver, chervoninnya, bіl during sichovipkannі. It also helps to keep the hygiene of state organs. Do not zastosovuvat cream for increased sensitivity to the components of the drug.
Medical interaction
Active drugs (Amphotericin, Nistatin) significantly reduce the effectiveness of Clorimazole with one-hour drug therapy, so it is not necessary to stop them all at once. No negative interactions with other drugs were observed after victorious medication. For the sake of protection, follow the vicorist cream one hour with other antibiotic ointments antifungal drugs can lead to allergies.
Side effects and overdose
With vicarious cream with Clotrimazole, there are often signs of side effects: stinging, liver, reddening of skin folds at the sites of application of the drug treatment. In some cases, fluffs, erythemi appear, and that peeling of the shkiri is swollen. Individual intolerance to the drug is manifested by croup. Vykoristannya medication in higher doses does not mean unsafe for life and health.
Contraindication
Zastosuvannya Clotrimazole is categorically contraindicated, as the patient has a history of:
- insufficiency of the work of the sciatica system as a whole;
- - increased sensitivity to the components of the drug;
- insufficiency of the liver;
- vіdkritі rani on the skies;
- allergic reactions.
especially vkazіvki
The antibiotic Clotrimazole is indicated for the treatment of fungal infections and other skin infections. The medicinal product is not suitable for use in ophthalmological practice, it should be unique to the contact cream with eyes and skin around them. For protection, the drug should be used in children up to 5 years of age. It is not possible to allow the cream to get into the wound on the affected mucous membranes. With the appearance of the first signs allergic reactions medical therapy with the drug slid pripiniti.
Vagity and lactation
No toxic effects of the drug were detected on the test, the stosuvanya was safely safe in all terms of vaginess. Therapeutic doses of the drug should be injected into the development of the fetus. It is recommended to use Clorimazole as a method of prevention of fungal infections for women, if they try to stay in the first trimester of pregnancy, if they may be unacceptably post-otochenya (for example, as a girl practicing in nursery or a likuvalny pledge). Zastosuvannya pid hour breastfeeding not fenced, as the cream is not used on milk worms.
Analogues
On the pharmacological market, there is a large number of medicinal preparations, which, for their activity, are similar to those of Clotrimazole, but are also distinguished by the release form, price, and warehouse. Acts from them can call out less side effects chi children shvidshe. The main analogues of Сlotrimazole є:
- Candidate. An antifungal medication that can have a wide range of effects on exposure to fungal microorganisms. The main active speech of Candida is clotrimazole - the form of speech is imidazole. The fact that the drug ushkozhuє membranes clitin fungi, zgіdno z vіdgukami vvvazhaetsya one of the shortest antifungal zabіv. Warehouse stock is close to 80 rubles.
- Kanizon. Likarsky zasib may have fungistatic and fungicidal effects, showing any fall in stagnant doses of the drug. Before the drug Kanizon may be sensitive to such groups of fungi: dermatophytes, mold fungi, blastomycetes and dysmorphic fungi, actinomycetes. The active component of galmui is the synthesis of speech molecules to ergosterol, which is necessary for the formation of cell membranes of pathogenic microorganisms. The price of the medical care should be 75 rubles per package.
Price
Before buying the drug, it is necessary to know how much the cost of Clotrimazole, equal price, choose the best. You can buy the drug in the online store for a proponated catalogue. Variation of Сlotrimazole to be deposited depending on the number of factors:
- percentage instead of active speech;
- concentration of clotrimazole;
- the nature and quality of additive ingredients;
- virobnik firm.
Video
Pathogenic fungi often become the cause of infection in the paths. Such a gynecological disease, like thrush (vaginal candidiasis), will require infection. effective drug for example, clotrimazole tablets. Among the reasons, which are prescribed by a doctor, which antifungal medication has its own advantages and nuances, if the varto tablets are blocked.
What is Clotrimazole
Gostra infection, which is a chronic form, ailments occur swedish glee zavdyaki drug from the group of similar imidazole. Clotrimazole is an antifungal agent for a wide range of applications, which is used in vaginal puffs, ointments, suppositories and other medicinal forms. Speech is active, as it has brought its effectiveness in treating some gynecological diseases, disrupting the synthesis of ergosterol, which makes the clitin membrane of the fungus, which destroys it.
Likewise, if the active ingredient helps to deform the clitin membrane, demonstrate Clotrimazole tablets according to the term for bacteria. Influencing the vibration of the components, which are necessary for the strengthening of membranes, the medicinal factor destroys the vitality of microorganisms, which provokes inflammation of the mucous membranes and skins. The main power of the drug to manifest itself is not at once: the symptoms of the disease of the female state system can be turbulent for a few days on the cob of victories, the docks will show themselves.
Indication for zastosuvannya.
The antifungal effect of the drug is indispensable in the treatment of a whole series of illnesses, and the stinginess is true: the sound of the sound and the clearly pronounced side effects. The active stably plisnyavih, yeast-like fungi, lichen, dermatophytitis drug is not less corrosive as antimicrobial susceptibility, which is the most significant growth of staphylococci, streptococci, gram-negative bacteria. In the practical gynecology room, indications before ingestion of Clotrimazole are as follows:
- thrush of stately paths;
- trichomoniasis;
- genital infections;
- sanitation of ancestral paths before birth;
- before surgical operation on state organs
Warehouse Clotrimazole
The basis of the drug preparation is to become one active speech - clotrimazole. Creamy, vaginal tablets with rounded edges to cover additional speech, yak establish a homogeneous structure. Why go to the warehouse of Clotrimazole, helping to boost your power? In an insignificant quantity, the following ingredients should be used:
- lactose;
- potato starch;
- sodium bicarbonate;
- adipic acid;
- colloidal silicon dioxide;
- magnesium stearate;
- sodium lauryl sulfate.
Yak zastosovuvati Clotrimazole
An important rule for the hour of treatment of gynecological illnesses is the time schedule. Clotrimazole can be used in gynecology intravaginally, that is, internally, and for which it is suitable like candles, and vaginal tablets. The standard scheme, which prescribes fahivets, tells you that you will need to take three tablets for a day. As a scheme of likuvannya transfer of the tizhnevy interval, taking one pill for doba. Її it is recommended to enter in the lower part, so that part of the faces can be seen by name.
Instructions for injecting Clotrimazole
The drug can be recommended by a doctor for the treatment of danes one-time or as a course, depending on the symptoms and severity of the disease. Appointments can be made individually, after reviewing the anamnesis. As if on the side of fahіvtsya vіdsutnі dodatkovі vkazіvki, then typical instructions for zastosuvannya Clotrimazole, to avoid infection, look like this:
- Read the instructions for additional dose and allowable therapy. Dotrimannya dozuvannya, hourly period є obov'yazkovim.
- Before the introduction of the pіguls at the pіhvu, dotrimuyuchis standards of hygiene, follow the hands.
- For clarity, the next step is to take a pose: lie on your back, bend your legs in your knees. The vaginal tablet is administered with a slight pressure, but gently.
- Lie down in such a position with a sprat of quills, so that the antifungal zasib evenly spreads.
Pid hour of vacancy
The period of winemaking for a child for a woman is due to the risk of the appearance of unacceptable symptoms. Some are respected by the norm, others are unimportant phenomena, such organisms can be spared with additional faces. On the aphids of an unstable hormonal background, the ignition process, similar to the symptoms of candidal vaginitis, is a frequent depression. How to get rid of the pain discomfort in the lower abdomen that visibly liver? Vykoristovuvaty vaginal tablets pіd h vagіtnosti, and before cim obov'yazkovo consult a gynecologist.
At menstruation
Although in the known term Clotrimazole with vaginess is a way of early sanitation of ancestral pathways before the birth of a child, then during menstruation the picture is different. The choice of this medicinal preparation for preventing the development of infection is not considered effective. Since Clotrimazole is not recommended during menstruation, then a therapeutic course of varto should be considered either until now, or after the completion of the cycle. The activity of speech will be minimal through the risk of taking pills, so the thrush clotrimazole will not bring any good result.
Overdose
As a way to prevent diseases caused by fungi - an affordable drug at a price. The use of vaginal tablets Clotrimazole for thrush can be taken with swedish clothes, but not without diagnosis, unacceptable symptoms, pain after the recommended dosing. The over-concentration of the disease caused an unfavorable reaction, which worsened the illness. An overdose of Clotrimazole for the body of a woman can lead to such nasledkіv, like a back, languor, arterial hypotension, kropivyanka.
Pobichna diya
It is recommended that the frequency of antifungal infection is not guaranteed against the appearance of unacceptable reactions. Weakening of infection female organism it is not possible to stand up for a long time to active speech, giving a signal about the blame for the unfortunate consequences of victorious medication with a path to discomfort in the sphere of the state organs and the milk follicle. Viniknennya side effects Clotrimazole is remembered for such signs:
- soreness in the clitoris;
- swelling of the mucous membrane of pikhvi;
- liver, sverbіzh, teasing the vulva;
- peeling;
- seep;
- non-acceptance of consideration of the hour of the statute act;
- liver in the department of state organs of a person.
Contraindication
In case of low illness, due to the possibility of transmission of infection by the state path, the course of therapy is required for the skin partner at once, but it does not result in a single hit. For some, the therapy will pass without a hitch, and for some, the drug may not be taken due to individual intolerance. Like and at a glance with be-like faces, follow the trail of foreign entries, or clarify the nuances with the fahivtsya. Є contraindication to Clotrimazole: use of vaginal tablets varto obmezhit or unique in such situations:
- Vіk up to 12 years;
- sensitivity to active speech;
- period of menstruation;
- in case of bloody visions from pikhvi (chronic, irregular);
- rotting, swelling, hanging, bulbs, wounds on the female organs;
- cold, fever;
- nausea, vomiting, diarrhea;
- back pain.
Interaction with other medical care
Antifungal drug treatment with a one-step active rechovina building galmuvate for other preparations. In the most important cases, it is necessary to take medicines of the current zastosuvannya, like Clotrimazole in tablets is included in the other category of diseases. As for the fight against infection, the drug prescribing this antifungal drug for a wide range of drugs, then, as fakhivets, vіn know, that vaginal tablets with tsієyu active speech, sho do not go with Nіstatin, Natamycin and
It is a real and proliferative phenomenon, if the intake of certain medications can greatly interfere with the effectiveness of clotrimazole. Interaction with others medicinal preparations in such cases it is unbearable, the process of dressing up will drag on for an hour, among such preparations - Dexamethasone. As well as the need to increase the antimycotic power of clotrimazole, then adding propyl ester of p-hydroxybenzoic acid to the dosage regimen will help achieve a good result, at which point it is necessary to take it at a high concentration.
Analogues
There is a variant of the vitchisny drug available, and one of the best antifungal drugs. Not a lot of words, which can be seen up to this group, may have the same power and spectrum, and yet they are analogues of Clotrimazole tablets. In vipadkah, if it is not possible to buy faces in a pharmacy, it can be replaced with similar methods from instead of such an active speech. Analogues of Clotrimazole are the following medicines:
- Candid;
- Kanesten;
- Kanizon;
- Candibene;
- Ganestan;
- Funginal.
The price of Clotrimazole tablets
The need for antifungal protection is determined by its effectiveness, safety, and availability. If I receive an urgent nutrition from the doctor, how much should clotrimazole cost? It would be wrong to assume that yoga can be bought in the Internet store as a contraceptive from the catalog. If there is a quality at stake, then it is cheaper to put it in an online pharmacy, for you know what faces or analogues will be in reality. The price of tablets Clotrimazole (100 mg), 6 pieces - varies from 20 to 55 rubles.
clotrimazole
International non-proprietary name
clotrimazole
Pharmaceutical form
warehouse
100 g cream revenge
speech is active clotrimazole 1 g,
additional speeches: cetostearyl alcohol, octyldodecanol, polysorbate 60, sorbitan stearate, synthetic spermaceti, benzyl alcohol, purified water.
Description
Uniform mass of white color
Pharmacotherapeutic group
Antifungal preparations for ovarian infection. Avoid imidazole and triazole. Clotrimazole.
ATX code D01AC01
Pharmacological authorities
Pharmacokinetics
After applying clotrimazole cream to the skin, clotrimazole is absorbed by the epidermis. Higher concentrations of clotrimazole are found in the horny and spiky balls of the epidermis, as well as in the papillae and the sacicular ball of the dermis. Clotrimazole sucks badly through the skin and mucous membranes and practically does not repair the systemic disease.
Clotrimazole is metabolized in the liver to inactive tracts, which are excreted in the feces.
Pharmacodynamics
Mechanism dії
Clotrimazole prinіchuє rіst and podіl kіtin. In small concentrations it is fungistatic, in high concentrations it is fungicidal. The antimycotic effect of clotrimazole is associated with impaired synthesis of ergosterol, which enters the warehouse of the clitin membrane of fungi, and binds with phospholipids of the clitin wall of the fungus.
Clinical studies have shown that the effect of ingestion of clotrimazole is similar to the effect of ingestion of similar imidazole - econazole and ketoconazole.
In fungal cells, clotrimazole also inhibits the biosynthesis of protein, fats, DNA, and polysaccharides, nucleic acids and increase the loss of potassium. You can ignore the activity of enzymes and biosynthesis of triglycerides and phospholipids in the stem cells. At high concentrations, clotrimazole is reduced to the extent of the cellular membrane in terms of mechanisms, as in the synthesis of sterols.
Clotrimazole, which is victorious for the treatment of infections caused by C. albicans, including the transformation of the blastophore into the її invasive form. Changes in the structure of the clitin membrane lead to the death of the clitin. Step in the injection of the drug to lie down in the degree of susceptibility to the microorganism to clotrimazole.
Activity spectrum
Clotrimazole is characterized by a wide spectrum of antifungal and antimicrobial activity, which can lead to the death of dermatophytes. (Epidermophyton floccosum, Microsporum canis, Trichophyton mentagrophytes, Trichophyton rubrum), yeast-like mushrooms (Candida sp., Cryptococcus neoformans), dimorphic fungi ( Coccidioides immitis, Histoplasma capsulatum, Paracoccidicides brasiliensis) and protozoa (Trichomonas vaginalis).
Clotrimazole may be antimicrobial for gram-positive microorganisms: Streptococcus, Staphylococcus, Gardnerella vaginalis and gram-negative micro-organisms ( Bacteroides). Does not spit on lactic acid bacteria ( Lactobacilli).
In vitro clotrimazole reduces reproduction Corynebacteria and gram-positive coci - for a few enterococci - at a concentration of 0.5-10 μg / ml to the substrate.
In vitro clotrimazole is widely fungistatic and fungicidal. Its effect on dermatophytes is similar to that of griseofulvin, but on organisms of the genus Candida - Polyeniv (amphothecin B and nystatin).
At concentrations below 1 µg/ml, clotrimazole inhibits more strains. Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum і microsporum canis.
At a concentration of 3 mcg / ml, clotrimazole inhibits the growth of more bacteria: Pitorosporum orbiculare, Aspergillus fumigatus, Candida species, including Candida albicans, deakі shtami Staphylococcus aureus, Streptococcus pyogenis, as well as deakі shtami Proteus vulgaris і Salmonella. Clotrimazole active against Sporotrix, Cryptococcus, Cefalosporium і Fusarium. Concentration more than 100 mcg/ml effective against Trichomonas vaginalis.
Clotrimazole-resistant strains are rarely seen, and only one description of strains with characteristic resistance. Candida Guilliermondi.
Daily reports about the resistance of the middle strains sensitive to clotrimazole after sowing. Candida albicansі Trichophyton mentagrophytes. No resistance to clotrimazole was suspected in strains C. albicans from resistance to polyene antibiotics.
Indication before zastosuvannya
Mistseve exaltation of skin infections on the surface of the hands, feet, body, homils and nig, called dermatophytes ( Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosumі Microsporum canis)
Visіvkopodіbny lichen, viklikaniy Malassezia furfur (Pityrosporum orbiculare) or Pityrosporum ovale)
Drijdzhovі іnfektsії (including Candidaі balanitis) skin curves and mucosal outer organs (articular lips, foreskin)
Method of stosuvannya that dose
Only for zovnіshny zastosuvannya.
The cream is applied with a thin ball on the skin of the skin 2-3 times a day and gently rubbed (beforehand, clean the skin for help with a neutral pH and get wet with a dry towel).
Trivality of rejoicing should be established from 2 to 4 days and fall due to the severity of illness, localization of pathological changes and the effectiveness of therapy.
Usі ііnfіkovanі oblastі can be аbоlеnі at once.
To avoid recurrence, therapy with Clotrimazole cream is recommended to be continued for at least 2 days after the onset of symptoms of illness.
Trivality of therapy
The treatment of dermatomycosis is carried out at least 4 times.
Treatment of infections caused by Candida- less than 2 tyzhnі.
Visivkopodіbny lichen is effectively enjoyed in case of miscarriage with a stretch of 1-3 days.
If the symptoms of illness do not change after 7 days of infection, it is necessary to consult a doctor.
Pobichna diya
The frequency of manifestation of side effects of the drug is determined as follows:
Even more often (≥1/10), often (≥1/100 and<1/10), нечасто (≥1/1000 и <1/100), редко (≥1/10000 и <1/1000), очень редко (<1/10000), неизвестно (недостаточно сведений для оценки).
Ridko
Contact allergic dermatitis, erythema
Allergic reactions (crop, zadishka, hypotension, restlessness)
Sverbіzh, visipannya, pukhirі, peeling shkіri, discomfort/bіl at the place of application, liver, swelling, teasing
Contraindication
Increased sensitivity to fluffy speech or to any component of the drug
Medical interactions
The drug can be negatively injected into latex contraceptives, ear-drinking and lowering their contraceptive capacity. Patients should try alternative methods of contraception as little as five days after completing the course of therapy with Clotrimazole.
Іntravagіnalne zastosuvannya drug formulation Clotrimazole i takrolіmus for priyah vnutrіshno (FK-506 іmunosuppresant) Mauger prizvoditi to pіdvischennya rіvnya takrolіmusu in plazmі krovі, y denote zv'yazku of patsієnti povinnі perebuvati pid retelnim perspicuity lіkarya for viniknennya simptomіv peredozuvannya takrolіmusom i for neobhіdnіstyu , yogo concentration in plasma.
especially vkazіvki
At the warehouse of the drug is cetostearyl alcohol, which can cause irritation of the skin (contact dermatitis).
Fertility
The study of the effect on the fertility of humans has not been carried out;
Vagity
There is a large number of data about the choice of clotrimazole in women. Studies on animals do not indicate direct or indirect side effects associated with reproductive toxicity. As a zapobіzhny zasіb, it is important to uniquely select clotrimazole for the first trimester of pregnancy.
lactation period
Evidence of pharmacodynamic/toxicological data in animals has shown evidence of clotrimazole/metabolites in milk. It is not recommended to breastfeed for an hour with clotrimazole.
Peculiarities of the injection of medical care for building construction by means of transport and potentially unsafe mechanisms
Clotrimazole cream is not injected, or it is slightly injected into the building by means of transport or potentially unsafe mechanisms.
Overdose
An overdose of the drug maloimovirne in conjunction with the drug form, the form of administration and low absorption of clotrimazole.
Symptoms: in times of non-transferred drug congestion, internal confusion, nausea, vomiting can occur.
Likuvannya: there is no specific antidote. If necessary, symptomatic relief.
Release form and packaging
20 g of the cream is placed in aluminum tubes with internal lacquer coating, sealed with membranes and covered with plastic caps that are screwed on.
1 tube at a time with instructions from the state sovereignty and Russian language is placed at the pack of cardboard.
Wash away the savings
Save at temperatures no higher than 25 ºС. Do not freeze chi.
Take care of the place inaccessible to children!
The term saving
Do not stop after the completion of the term of applicability.
Wash your permits from pharmacies
Without recipe
Virobnik/Pakuvalnik
Vlasnik of registration certificate
GlaxoSmithKline Pharmaceuticals S.A., Poland
(189 Grunwaldzka Street, 60-322 Poznan)
Addresses of organizations that accept claims on the territory of the Republic of Kazakhstan regarding the quality of products (goods)
Representative office of GlaxoSmithKline Export Ltd in Kazakhstan
050059, m. Almaty, st. Furmanova, 273
Phone number: +7 727 258 28 92, +7 727 259 09 96
Fax number: + 7 727 258 28 90
Email addresses: [email protected]
Approved instructionYufrom medical zastosuvannya to marvel also at the site www.dari.kz