Navischo vikoristovuyut atropine. Ways to win atropine. Congestion with vagity and breastfeeding


m-Cholinolytics Ophthalmological care

Pharmacology

Pharmacological activity - cholinolytic.

Blocking m-cholinergic receptors. Viklikaє mydriasis, paralysis of acomodation, movement of the internal pressure, tachycardia, xerostomia. Ignore the secretion of bronchial and ductal, sweat cavities. Relaxation of the smooth muscles of the bronchi, mucosal-intestinal tract, zhovkota sichovovidnyh systems - spasmolytic effect. Destroys (large doses) the central nervous system.

Stopping speech Atropine

Virazkov's ailment of the duct of the duodenum, pylorospasm, cholelithiasis, cholecystitis, hostrial pancreatitis, hypersalivation (parkinsonism, poisoning with salts of important metals, with dental implants), irritable bowel syndrome, intestinal colic, and l oatrial block, proximal AV block, electrical activity of the ventricles without a pulse , asystole) for preoperative premedication; disruption by m-cholinergic stimulants and anticholinesterase LDs (reverse and irreversible diseases), incl. organophosphates; with radiological findings of the intestinal tract (if there is a need for a change in the tone of the intestinal tract), bronchial asthma, bronchitis with hyperproduction of mucus, bronchospasm, laryngospasm (prevention).

Side effects of speech Atropine

System effects

From the side of the nervous system and organs are sensitive: headache, confusion, sleeplessness, confusion of information, euphoria, hallucinations, mydriasis, paralysis of accommodation, impaired tactile sensation.

From the side of the cardiovascular system and blood (hematopoiesis, hemostasis): sinus tachycardia, exacerbation of myocardial ischemia through supramundane tachycardia, tympanic tachycardia and tympanic fibrillation.

From the side of the organs SHKT: xerostomia, constipation.

Platifilin Pharmacological group of speech Platifilin

m-Cholinolytics Myotropic spasmolytics

Pharmacology

Pharmacological activity - antispasmodic, vasodilating, sedative.

Blocking m-cholinergic receptors and direct relaxing injection on smooth surfaces. Expanding the vessels, lowering the tone of the smooth muscles of the biliary ducts and the biliary tract, bronchial tubes, exacerbating mydriasis.

Shvidko and dosit povmoktuєtsya from the shlunkovo-intestinal tract. It is easy to pass through histohematic barriers, clitin and synaptic membranes. With the introduction of high doses, it accumulates in the tissues of the central nervous system at significant concentrations. Excreted by sichoid and herbal systems

Zastosuvannya speech Platifilin

Spasms of smooth muscles in case of viral disease of the duct and twelfth intestine, intestinal, hepatic and narcotic colic, bronchial asthma, hypertensive ailment, angina pectoris, spasms of the vessels of the brain, pain syndrome in pancreatitis, pancreatic coma, dyskinesia ia zhovchovifayuchikh, laziness with acetone, boric acid, mic acids, mish'yak, reserpine, carry-over (imperative posivi), in ophthalmic practice - for expanding the range in diagnostic and literal purposes.

Side speeches Platifilin

Dryness in the mouth, widening of the jaws, impaired accommodation, heartbeat, decreased arterial pressure, buttocks, atony of the intestines, stuttering of the cut, agitation, sudomi.

Pharmacological group

m-cholinolytics

Pharmacological activity

Pharmacological activity - spasmolytic.

Interacting with m-cholinergic receptors, screening their mediator (acetylcholine).

Indication for zastosuvannya.

Spasm of the smooth muscles of the internal organs (viraz's ailment of the tube and duodenum, chronic gastritis, nirkova and liver colic); hypersecretion of the sinuses and bronchial ulcers.

Pobichna diya

Dryness in the mouth, constipation, difficulty in secession.

Eufilin

Pharmacological group Adenosinergic diseases

Pharmacological activity

Broncholitic zasib, similar to xanthine; inhibition of phosphodiesterase, increased accumulation of cyclic adenosine monophosphate in tissues, blocking adenosine (purine) receptors; lowering the intake of calcium ions through the channels of cellular membranes, changing the transient activity of smooth muscles. Relaxes the muscles of the bronchi, improves mucociliary clearance, stimulates the contraction of the diaphragm, improves the function of the dichal and intercostal membranes, stimulates the dichal center, increases sensitivity to carbon dioxide and improves the alveolar well, ventilation, which in the end bag should be reduced to a lower elasticity. Normalizing the dichal function, reducing the blood sourness and reducing the concentration of carbonic acid. To repair a stimulating injection on the activity of the heart, increasing the strength of that number of heart rates, increasing the coronary blood flow and the need for the myocardium in the heart

Atropine is an antispasmodic and antichilinergic drug. As an active component, it is an otruyny alkaloid, present in the leaves and native plants of the family Solanaceae. The main principle of the diuretic drug is based on the ability to block the cholinergic system of the body, which is located in the heart meat and organs, which can damage smooth muscles.

Pharmaceutical form

The pharmaceutical preparation Atropine is being developed by pharmacological companies in the form of injection for injection and in the form of eyedrops.

Description of warehouse

As an active component, it is independent of the medicinal form of acting as atropine sulfate. The achievement of the necessary medical formula for the safety of additional speech - physiological analysis.

Design a clear color scheme, do not allow a siege to take place in the process of saving. The cloudiness of the warehouse may be evidence of the wrong taking of the medication.

Pharmacological group

The drug Atropine is included in the group of antispasmodic and anticholinergic agents. The active component of the drug warehouse is rapidly rozpodіlyaєtsya in the organism of the patient and is introduced from the liver for the help of enzymatic hydrolysis. The indicator of binding from plasma proteins to become close to 18%. Do not forget about the health of speech to actively fill the placental barrier and penetrate breast milk. The period of napіvvivennya likarskogo zasobu to become two years. The correct dose should be taken from the patient's body for help.

Indication before zastosuvannya

Atropine ensures a change in the secretory function of the salt and a spice of relaxation of the smooth muscles. With a different warehouse, the format of the eye drops is expanded and the internal pressure is moved. Paralysis of accommodation is protected. If the person who receives it is safe to speed up the awakening of the heart activity, such an effect can be reached for the heart of the warehouse to put pressure on the bloating nerve without interruption. The drug is directly injected into the central nervous system, ensuring the activation of the dichal center. With varying toxic doses, it is possible to exacerbate rukhovogo and mental arousal.

A transfer of evidence before receiving a loan can be filed as follows:

  • virazkovі urazhennya sluice and duodenal ulcer;
  • spasm of the zhovchnyh duct;
  • spasms of the organs of the dichal system;
  • parkinsonism;
  • poisoning with salts of important metals;
  • bradycardia;
  • nirkov ring;
  • intestinal ring;
  • irritated small intestine syndrome;
  • bronchospasm;
  • laryngospasm.

Atropine can be used during low radiological examinations of the mucosal-intestinal tract before performing other surgical procedures in ophthalmology.

for grown-ups

The drug Atropine can be taken by patients of the category in the minds of the current contraindication until zastosuvannya. Individuals with a frail age often need dose adjustment to minimize the risk of aggravation on the background of the disease. In case of damage to the liver, the warehouse zastosovuєtsya with the promotion of protection.

for children

Likarsky zasib can win in pediatric practice for the recognition of fahivtsya. According to the pretrial rules of increased care, children of the early age are prescribed to persons with weakened immunity. The drug can cause a change in the intensity of processes in the production of bronchial secretions, against which background it is possible to eliminate plugs in the bronchi. Warehouse not vikoristovuyut with serious lesions of the brain, with cerebral palsy.

Atropine can cross the placental barrier. Control over the follow-up to the process of stocking the warehouse for the first hour of vacancy was not carried out. Warehouse not vikoristovuyut during the period of vaginess for intravenous administration through the possibility of development of tachycardia in the fetus. The active component of the medicinal product in a small amount can penetrate breast milk.

Contraindication

Warehouse is not assigned to patients with elevated sensitivity to fluent speech.

Zastosuvannya that dozi

The mode of dosing, the frequency and the frequency of the course are set by the doctor in an individual order. Failure to follow these recommendations can cause significant complications.

for grown-ups

The recommended dose for older patients is 300 mcg through the skin for 4-6 years. With the use of bradycardia, the warehouse is prescribed to mature patients at a dose of 0.5 - 1 mg. If necessary, repeat the introduction after 5 whilins. For premedication - 400-600 mcg one-time.

for children

For the development of bradycardia in children of all age, the dose is 10 mcg/kg of the patient's body.

for women and during lactation

In the period of vagity, the warehouse vicorates at doses that are recommended for mature patients for recognition of fahivtsya.

Pobichna diya

With systemic administration, the following reactions may occur:

  • dry mouth empty;
  • tachycardia;
  • complication of sechovipkannya;
  • photophobia;
  • zamorochennya;
  • damage to the tactile sprinyattya;
  • accommodation paralysis;
  • midriaz.

When vikoristanny ophthalmic drops, side effects can be as follows:

  • swollen shkiri povik;
  • hypermia;
  • swollen conjunctivitis;
  • photophobia;
  • tachycardia.

Interaction with other medical care

Data should be combined with other medicines daily. Possibility of a well-kept wine storage with other medical procedures is determined in an individual order.

especially vkazіvki

During the period of drug intake Atropin, the patient is to be blamed for the care taken by transport means and during the period of work with folding mechanisms.

Overdose

When vikoristanny in doses that are regulated by the instructions, the possibility of overdosing is reduced to a minimum. At times of overdose of the recommended doses, the patient may suffer self-esteem. For the use of side reactions that appear, sedative drugs may be used. If you show a severe reaction, the patient is warned to seek emergency medical assistance.

Wash away the savings

The medical bill is sold to the population through a network of pharmacies for the presence of a prescription. Warehouse should be kept at a temperature not higher than 25 degrees at protected access for children. Take a glass of drops after opening the packaging and take it away from the refrigerator.

Analogues

Lіkarskiy zasіb Atropin has no structural analogues in fluffy speech. Choose an adequate replacement for the impossibility of victorious zasobu Atropin can be a drug.

Price

Vartist Atropin to become the average of 50 rubles. Prices vary from 13 to 55 rubles.

The drug Atropin reduces the tone of the internal mucous membranes of the bronchi, the shunt and the sieve mucus. Changes in the secretion of sinus, sweat and bronchial congestion are prescribed. It is necessary to know in which doses the faces are taken, and if the stench may have side effects on the body.

Headache for Atropin - blocking of M-cholinergic receptors. The drug is to change the secretion of the slough in case of bronchial ailments. Also, Atropin to increase the heart rate for a therapeutic effect. Faces can reduce the tone in the bronchi and empty stomach. If the patient has a flaccid nerve tone, then Atropine is even stronger. Faces are poured into the expansion of the eyes in the eyes. Tse vіdbuvaєtsya at the moment of relaxation of m'yazіv in the shell of the eye.

Doctors prescribe Atropine as a symptomatic therapy for such illnesses:

  • Virazka shlonk;
  • Problems with the twelve-fingered intestine;
  • hostile pancreatitis;
  • At the moment of pylorospasm;
  • For therapy of zhovchnokam'yanoy ailments;
  • Treatment for cholecystitis;
  • Violent spasms in the intestines;
  • Problems with sichway paths;
  • Severe attacks of bronchial asthma;
  • To improve the tone of the nerve under the hour of bradycardia;
  • To reduce the tone of the activity of organs under the hour of X-ray.

Also, the drug can be considered an injectable drug for the following purposes:

  1. Before the introduction of anesthesia at the time of surgery;
  2. To relieve bronchial spasms in surgical intervention;
  3. To reduce the secretion of the burrow;
  4. Understanding the reflex reaction;
  5. It is prescribed as an antidote for overdose of cholinergic drugs.

In some ways, the choice of Atropin is unsafe for a healthy patient. Doctors pick up faces in such situations:

  • Strong allergy to any component in the warehouse;
  • Problems with the heart system;
  • Blame a flashy arrhythmia;
  • attack tachycardia;
  • Deficiency in a robotic heart;
  • Ischemic attacks;
  • Unsafe with mitral stenosis;
  • Not prescribed for severe stage of arterial hypertension;
  • How can a patient be bleeding;
  • Unsafe drug for thyrotoxicosis;
  • Not prescribed for hyperthermic syndrome;
  • How does the patient have problems with the tube;
  • Unsafe with glaucoma;
  • It is not prescribed for problems with nirkami and liver;
  • Like the patient has a part of the cut;
  • Unsafe with serious brain damage.

If you try to beat the drug in specific situations, it can cause harm to the body. Obov'yazkovo pass obstezhennya, so that Atropin is correctly beaten.

It is necessary to know with which drugs Atropine is insane or it can cause side effects. Axis for the latest list of words:

  • Vikoristannya together with MAO inhibitors to bring to a change in the rhythm of the heart;
  • Zastosuvannya Atropin z Khinidine inducing an increase in cholinolytic disease;
  • If you take the drug at once from tannin, then weaken the effect of both speeches;
  • Atropine reduces the analgesic effect of conventional opiates;
  • The drug changes the hour of drug use;
  • Parallel intake of Diphenhydramine potentiates the effect of Atropine;
  • Vykoristannya haloperidol lead to zbіlshennya vice in the middle of the eye;
  • Zastosuvannya at once from sertraline viklikaє feel like depression and depression;
  • With the help of penicillin, bring both faces to strength;
  • If you mix Atropin together with ketoconazole, it will change the blood circulation.

So the fahіvtsі saw low іnshih vzaєmodіy, on yakі it is necessary to show respect before the reception:

  1. The drug Atapulgіt will change the exuberant effect of Atropin;
  2. Faces will, with parallel administration, reduce the therapeutic effect of Pilocarpina;
  3. When vikoristannі octadine change the effect of Atropin;
  4. How to win the faces at once from sulfanamide methods, there may be a big problem with nirk and liver;
  5. Parallel intake of potassium preparations to bring up to the level of the tube. It can also cause bleeding;
  6. Diagnosis of the drug Atropine is possible when taking antidepressants, Amantadine and Fenotiazine;
  7. Be-yakі іnshі lіkarskі zasobi will be more smoky and children after the reception of Atropin.

If a patient takes other preparations for therapy, he needs to correct the dosage or take a dose. Only the doctor is guilty of virishiti.

Doctors saw a low illness, for which Atropine is prescribed with great care. In this case, the doctor is guilty of controlling the patient's state and regulating the dosing. The axis is a list of the main ailments, with which the drug can be damaged:

  • Cerebral palsy in children;
  • Problems of sechoviprosy;
  • Down's illness;
  • With hernias in the grass zone;
  • Be it a stage of virazic colitis;
  • At the moment of megacolonies;
  • Preservation for dosing to patients in the frail;
  • At the start of the stage of illness, legenia;
  • For children with autonomic neuropathy.

Patients with such ailments are obligated to follow the camp of health after zastosuvannya Atropin and see the doctor.

Physicians do not allow Atropin to be victorious for female women, whatever the term. Also, do not stop the drug at the time of breastfeeding. Scientists have brought that toxic speech can be consumed through milk to a child. Tse prizvede to strong allergies and health complications.

Driving a car pid hour

Be aware that Atropine has side effects such as confusion and mild hallucinations. The very same varto utrimatisya in the caravannya by car until the end of therapy. Doctors to please patients also do not work with mechanisms, as they require a great concentration of respect.

Atropine can be administered by the intravenous, intravenous, and subcutaneous methods. To reduce heart rate and change in bronchial ulcers, doctors prescribe 0.5 mg of the drug in case of a visible subcutaneous injection. It is necessary to administer it a year before anesthesia with morphine at once.

In cases of severe cholinergic disorders, inject the drug at a dose of 2 mg internally. It is necessary to administer Atropine to the skin in the first place. Apply the insertion of the liqiv following the reddening of the shkiri, or in the event of a tachycardia attack. In case of a severe stage of illness, vicorate the preparation 1-2 times.

The maximum dose for grown-up people is 3 mg per doba. 1 mg of Atropine can be given at a time. For children, it is selected individually by a doctor. Vaughn lie down in the form of a vіku that vag of the baby, and also in the stage of illness. For the protection of the next zastosovuvat dosing for patients of the frail age.

If a person has side effects, the doctor is guilty of changing the dose of Atropine or changing the frequency of injections.

If you administer too much of the drug to the patient, it may lead to worsened health problems. The first signs of overdose appear in such symptoms:

  1. Strongly visible nudoti, vomiting;
  2. The patient's vice decreases;
  3. Vinica tremor;
  4. Lyudina vodchuvaє peresbudzhennya;
  5. Judge strongly;
  6. At night it’s difficult to sip;
  7. Hallucinations may occur;
  8. The patient becomes nervous and drastic;
  9. Blame hyperthermia;
  10. The process of gnosis in the nervous system;
  11. Decreased activity in the dichal zone.

As soon as the patient sees such symptoms, he may once again take Atropine and turn to the hospital. Doctors are guilty of promptly promit the tube and introduce cholinergic drugs into the body. With symptoms of hyperthermia, it is necessary to wipe the patient with water towels and use antipyretic preparations.

As if a person is aware of that fear, the doctor prescribes injections of thiopental. You can also take Physostigmine. In case of glaucoma, the patient is guilty of digging Pilocarpine in the eyeball. At this point, you can work with an injection of Prozerin 3 times a day. The patient may be out of the clinic only after all the unacceptable symptoms pass.

Adverse reactions to the drug

In the instructions from the zastosuvannya, you can add all the side effects of the drug. Sound aggravated blame in case of individual intolerance to the liquor, or dependent dose to the liquor.

De z'are?Pobichna diya
The slug may have such side effectsSeeing dryness in the mouth;
Strong spraga;
Change the taste of the eyes to the reception of the hedgehog;
Problems with motility in the intestines;
Decreased tone in zhovchi;
Blame dysphagia;
Problems of sechoviprosy.
At the heart zone, you can start so foldedattack tachycardia;
Strong arrhythmia;
attack of ischemic disorder;
The appearance of the patient becomes a chervonim;
Seems like a rush of blood to the body.
In the nervous system, there are such side effectsattack a strong headache;
The patient is confused in the head;
Blame a little nervousness and fear;
It is important for people to get hoarse at night.
Zir can start so complicatedThe patient's eyes expand;
Blame photophobia;
attack paralysis of accommodation;
There is a vice in the middle of the eyes;
The clarity of the dawn falls swiftly.
The dichal system has such side effects.Reduced bronchial tone;
The phlegm becomes more viscous;
It is important for the patient to cough.
There are such side effects on the screen:Chervony visip on the body;
Viniknenny kropiv'yanki;
Manifest exfoliative dermatitis;
Strong allergy to the warehouse of liquids.
Other side effects on the drugThe patient begins to sweat less;
The shkira at the entrance becomes dry;
Vinica dysarthria;
Shkіra can be blackened through sensitivity to the warehouse.

If any side effects are detected, it is necessary to inject the drug. The doctor can determine the reason for such a reaction. It is possible, necessary to reduce the dosage or replace Atropine by a similar method.

Keep the drug only in the original packaging. It is important to trim the ampoules at a temperature of three times more than +25 degrees and at least +15 degrees. Do not put Atropin near the refrigerator at any time. It is important that the children could not get enough faces to take the middle. The term for the attachment of ampoules is three times more than 3 years from the moment of extraction. Robiti іn'єktsії, yakscho Atropin є prostrochenim.

Price for the drug

At the same time, you can get Atropin from looking at the ampoules from any pharmacy. Acts of a pharmacist should be recognized by a doctor with accurate dosing. The average price of the drug is 70 to 90 rubles. For qiu vartist you can get 1 ampoule of 0.1-hundredth grade.

Gross formula

C 17 H 23 N 03

Pharmacological group of speech Atropine

Nosological classification (MKH-10)

CAS code

51-55-8

Characteristics of speech Atropine

Atropine sulfate is a white crystalline abo-granular powder, odorless. Easily soluble in water and ethanol, practically insoluble in chloroform and ether.

Pharmacology

Pharmacological activity- cholinolytic.

Blocking m-cholinergic receptors. Viklikaє mydriasis, paralysis of acomodation, movement of the internal pressure, tachycardia, xerostomia. Ignore the secretion of bronchial and ductal, sweat cavities. Relaxation of the smooth muscles of the bronchi, mucosal-intestinal tract, zhovchota sichovovidnoy systems - spasmolytic effect. Destroys (large doses) the central nervous system. After intravenous administration, the maximum effect is manifested after 2-4 minutes, after oral administration (in the form of droplets) after 30 minutes. In the blood, 18% binds with plasma proteins. Pass through the blood-brain barrier. Seen by nirkami (50% - in the same look).

Stopping speech Atropine

Virazkov's ailment of the duct of the duodenum, pylorospasm, cholelithiasis, cholecystitis, hostrial pancreatitis, hypersalivation (parkinsonism, poisoning with salts of important metals, with dental implants), irritable bowel syndrome, intestinal colic, and l oatrial block, proximal AV block, electrical activity of the ducts without pulse, asystole) for preoperative premedication; disruption by m-cholinergic stimulants and anticholinesterase LDs (reverse and irreversible diseases), incl. organophosphates; with radiological findings of the intestinal tract (if there is a need for a change in the tone of the intestinal tract), bronchial asthma, bronchitis with hyperproduction of mucus, bronchospasm, laryngospasm (prevention).

In ophthalmology. To expand the range of the reach of accommodative paralysis (definition of true refraction of the eye, maintenance of the fundus of the eye), the creation of functional calm in case of inflammatory diseases and injuries of the eye (iritis, iridocyclitis, choriosideitis, keratitis, thromboembolism and spasm central artery of the sitkivka).

Contraindication

Hypersensitivity, for ophthalmological forms - subcutaneous glaucoma (including with suspected glaucoma), subcutaneous glaucoma, keratoconus, childish glaucoma (1% of cases - up to 7 years).

Frozen until zastosuvannya

Illness of the cardiovascular system, with any increase in heart rate, may be unbearable: fleeting arrhythmia, tachycardia, chronic heart failure, IXC, mitral stenosis, arterial hypertension, acute bleeding; thyrotoxicosis (maybe worse tachycardia); increased body temperature (it is possible to move further away due to strangulation of the activity of sweat deposits); reflux esophagitis, herniation of the stravochid opening of the diaphragm, which is associated with reflux esophagitis (decreased motility of the stravochodal valve and the weakening of the lower stravochid sphincter can help improve the esophagus and gastroesophageal al relux); illness of the HKT, which is accompanied by obstruction: achalasia of the stravohod, stenosis of the hiatus (possible decrease in motility and tone, which can lead to obstruction and obstruction of evacuation in the place of the drain); intestinal atony in ailments of a frail age or weakened ailments (possible development of obstruction), paralytic intestinal obstruction (possible development of obstruction); illness with increased intraocular pressure: zakritokutova (mydriatic effect, which can lead to an increase in intraocular pressure, may lead to a hostile attack) and acute glaucoma (mydriatic effect may be secondary to deake nya vnutrishnyoochnogo vice, may need correction of therapy); nonspecific virazkovy colitis (high doses can aggravate intestinal motility, leading to remission of paralytic intestinal obstruction; in addition, it can manifest or worsen such a severe condition, like toxic megacolon); dryness in the mouth (trivale zastosuvannya may be more likely to increase the severity of xerostomia); hepatic insufficiency (decreased metabolism) and nirk insufficiency (risk of development of side effects due to reduced excretion); chronic infection of the leg, especially in children of a young age and weakened ailments (changes in bronchial secretion can lead to a thickening of the secretion and elimination of plugs in the bronchi); myasthenia (stand can be affected by inhibition of diacetylcholine); hypertrophy of the anterior ridge without obstruction of the sieve passages, slashing of the sieve or scaling up to it, or illness, which is accompanied by obstruction of the sieve paths (including the neck of the sieve laceration due to hypertrophy ії premіhurovoї zoloza); preeclampsia (possible worsening of arterial hypertension); cerebral palsy in children, infantile cerebral palsy, Down's disease (reaction to anticholinergic LZ increases). For ophthalmological forms (dodatkovo) - age older than 40 years (nebezpeka manifest undiagnosed glaucoma), synechia of the iris membrane.

Congestion with vagity and breastfeeding

Side effects of speech Atropine

System effects

From the side of the nervous system and organs are sensitive: headache, confusion, sleeplessness, confusion of information, euphoria, hallucinations, mydriasis, paralysis of accommodation, impaired tactile sensation.

From the side of the cardiovascular system and blood (hematopoiesis, hemostasis): sinus tachycardia, exacerbation of myocardial ischemia through supramundane tachycardia, tympanic tachycardia and tympanic fibrillation.

From the side of the organs of the shlunkovo-intestinal tract: xerostomia, constipation.

Other: fever, atony of the intestines and sich mihur, zatrimka sichovipkannya, photophobia.

Mіstsevі efekti: minusche pokolyuvannya i podvischennya vnutrishnoochnogo vice; in case of trivial zastosuvanni - teasing, hyperemia of the hips; hyperemia and swelling of the conjunctivitis, development of the conjunctivitis, mydriasis and paralysis of accommodation.

When administered in single doses<0,5 мг возможна парадоксальная реакция, связанная с активацией парасимпатического отдела вегетативной нервной системы (брадикардия, замедление AV проводимости).

Interaction

Weaken the effect of m-cholinomimetics and anticholinesterase effects. LZ with anticholinergic activity potentiate atropine. With one-hour administration of antacids, which eliminate Al 3+ or Ca 2+ , the absorption of atropine from HCT changes. Diphenhydramine and promethazine are effective against atropine. Imoving the development of systemic side effects promotes tricyclic antidepressants, phenothiazines, amantadine, quinidine, antihistamines and other drugs with m-cholinoblocking powers. Nitrati zbіlshhuyt ymovіrnіst pіdvishchennya vnutrishnoochnogo vice. Atropine alters the absorption parameters of mexiletine and levodopa.

Ways to enter

Internally, in / in, in / m, PC, conjunctival, subconjunctival or parabulbarno path to electrophoresis. The ointment is placed behind the veki.

Zapobіzhnі come in speech Atropin

In patients with distal type AV block (with wide QRS complexes), atropine has little effect and is not recommended.

When instilling into the conjunctival sac, it is necessary to press the lower lacrimal point to avoid getting into the nasopharynx. In case of subconjunctival or parabulbar introduction of a change in tachycardia, Validol is indicated as an additional dose.

The iris is intensively pigmented to dilatation, and in order to achieve the effect, it is necessary to increase the concentration or the frequency of administration, which should be afraid of an overdose of the drugs.

Expansion of the eyes can provoke a hostile attack of glaucoma in especially older than 60 years and people with hypermetropia, slender to glaucoma in starvation, because the stench may sting the anterior chamber.

Atropine Sulfate (or simply Atropine) - ce mydriatic and spasmolytic zasib that viroblyayetsya in various medicinal forms. This diversity can allow you to win the drug for recognition in any handy-looking person - tablets or tablets for injections. Speech of the chemical structure can be distinguished to the group of alkaloids and it is important in the solanaceous families of roslins. Krasen (abo belladonna) is brought to the largest of their representatives.

Warehouse for the drug disintegration of chemical and synthetic slabs at factories for special technologies. Atropine Sulfate is included in the pharmacological group of cholinergics, adjusted for the blockade of M-cholinergic receptors. Faces zastosovuyut is important for relieving stress in smooth lingual fabric and spastic states. The drug is known for prevention and treatment of ophthalmic diseases.

Atropine indication: before congestion

Atropine zastosovuєtsya in the most addictive purposes. The latest range of directives for implantation is especially indicated in the instructions, which can be found in the skin packaging.

Become, for which the drug is prescribed:

  • Spasm of the shunt collar
  • Virazka chi bowel
  • Colic caused by stones in the mush
  • Kishkova, nirkova chi zhovchna Kolka
  • Igniting processes in the sub-shlunkovy shaft and zhovchny mukhuri
  • Mustache forms of bradycardia
  • rotten bowel syndrome
  • Bronchospasm, caused by an allergic or asthmatic state.

Often, atropine is administered before surgery under anesthesia. To fight the change of sleep.

In X-ray diagnostics of the organs of the mucosal-intestinal tract, the drug is also detected. Shards of faces change the efficiency of robotic burrows, which can stop and in case of pathology of sweating. As an antidote, the medicine zastosovuetsya when it is poisoned by deaky bruises.

Ophthalmologists zastosovuyut drug for mydriasis, so special effect of the expansion of the chin. It is necessary to work with the method of removing access to the internal bottom of the patient and the necessary manipulations and diagnostics. Also, wines are victorious for the exaltation of inflamedness, that sickness of the horn and the circular shell of the eye. After an injury, or an operation on the full-time apple, Atropine drops relax to the necessary ointment of the eyes and help reach the best possible clothes, taking care of the rest of the calm.

Oskіlki drug podlyagaє kіlkisnym obіku in pharmacies, it is impossible to buy it without a doctor's prescription. In case of contraindications up to the components of Atropin, the drug can prescribe numbers that include the group of acute and narcotic diseases (group A).

Atropine sulfate

Representations of the drug can be taken for inhalation with problems of bronchospasm, administered intravenously and internally, orally orally as a finely dispersed aerosol.

Rozchin for injections 0.1% to be administered twice a day. If you take it internally, once a day is enough, also 0.1%. If necessary, the dosage of Atropine aerosol is discussed in advance with the doctor and, as a rule, becomes the same 0.1%. Victory required quantity once, sound 3-5 whilins until the attack is relieved.

Atropine drops for eyes

For ophthalmic infusion Atropine full-time rozchin you can get in pharmacies dosing 5 ml of 1% retail. When the eye is inflamed, the eyes are prescribed 5-6 times a day for the eyes of the eye, for the eyes of the eye, 1-2 doses are prescribed. In such weathers, medriaz trivaє close to tyzhnya and nastaє already for the first year after the vikoristannya krapel.

If a patient goes back to the ophthalmologist for the method of diagnostics, the severity of medriasis is regulated for an additional dose, and such an effect lasts no more than two days. Deyakі vyrobniki vypuskayut ochnі plіvki, gelі and ointment, scho vengeance of the main speech.

Mechanism for Atropine

M-cholinergic receptors are actively blocked for the help of the special ability of Atropine, which underlies the mechanism of yoga practice. Qi receptors are found most importantly in the tissues of smooth muscles in the endings of parasympathetic nerve fibers. The specific mechanism of injection of the drug provokes the attack pharmacological effects:

  • Calling for frequent heart rate
  • Click to expand the zone
  • Normalization of the permeability of nerve impulses of the heart.
  • Ignore the secretion of sweat, sinus, herbal and bronchial ulcers.
  • Relaxation of the smooth mucus of the organs of the mucosal-intestinal tract, bronchi and the sacicular system.

Such a wide range of serious effects in pharmacology leads to the development of side effects in the future, and also explains the long list of contraindications before the drug is taken.

Atropine is contraindicated

Instructions for faces to talk about all situations, if the drug can lead to wrong health, then it is necessary to win it over with a singing guard or turn it off from a complex treatment.

Contraindication:

  • Keratoconus
  • Bowel obstruction
  • Week up to 7 years
  • Pathology of nirok
  • Heart rhythm disruption
  • Participate in lower heartbeat
  • Organic chi pathological damage to the heart mass
  • Allergy to the drug
  • Individual intolerance to one or more components of the drug
  • Reflux - esophagitis
  • Paralysis of the small intestine
  • Viklikaє disruption of the sechoviprostate adenoma of the prostate
  • Glaucoma

In case of overdosing or undertreatment, the rule of thumb for the drug, and also in case of hypersensitivity to the body, it is possible to clear up the offensive side effects:

  • allergic reaction
  • tachycardia
  • disruption of the oral function
  • head bіl
  • dry mouth
  • zamorochennya
  • problems

Only a few drugs on the basis of the conducted diagnostics and analyzes can indicate injection of Atropine, to get rid of negative sledkіv in the form of uncontrolled vikoristannya likіv

Atropine in tablets

The form of release of Atropin, which is widely administered, is tablets. Їx is prescribed to reduce the secretion of herbal enzymes in complex polishing of virazka intestines that slough.

Dosing of Atropine tablets- 0.5 mg. The stench is accepted for five years before arrival, or in 1-2 years after it. The dose is determined by the doctor individually for the skin patient. The main guideline of a gastroenterologist in the selection of dosing is a symptom of dryness in the patient's mouth on the basis of taking Atropine tablets. This symptomatology is about those who further increase the dose of the drug, threatening with strong negative infusions.

Overdosing with Atropine

How to inject the drug uncontrollably, blame poisoning on aphids overdosing, which is indicated by the onset of symptoms:

  • Constipation
  • Blew up that tediousness
  • Slimy blackness and dryness
  • Arrhythmia and tachycardia
  • More frequent breathing
  • Tremtynnya kіntsivok
  • Impaired kovtal reflex, hoarseness
  • Damaged m'azovih fabrics
  • Vtrata svіdomosti
  • Sudomi

In case of direct abuse, either in cases of the most severe overdose of the patient's drug, it can be fatal, causing paralysis of the respiratory muscles. In order to avoid such rare situations, it is possible to get a face only by presenting a valid document in the pharmacy, which officially allows the pharmacist to sell the drug.

Atropine Vidguki

The pharmacological effect of the drug outweighs the problems due to overdose or wrong assumptions, the positive results are still more numerous, although they are diluted with unacceptable symptoms and negative symptoms.

So, as a replacement for these drugs came more modern and effective preparations with a richly smaller spectrum of side effects, the opinions of fahivtsiv about them are also ambiguous.

Atropine analogues

Atromed is accepted as an analogue of Atropin for a warehouse sign, but it is not possible to use it in drops for the eyes, it is not suitable for other therapeutic directives. To replace Atropine, you can vicorate extracts or tinctures of beladoni, but for the sake of washing your mind beforehand, please likuvannya with a doctor.

With a different warehouse, but with a similar pharmacological effect, such preparations can be:

  • Darifenacin
  • Platifilin
  • Cyclodol
  • Pirenzepine

Atropine for vagity

In such a tendentious position, as a woman taking Atropin, it is necessary to uniquely or victoriously, if necessary, and under the strict control of the doctor. In case of fluctuating speech, the drug penetrated through the barrier of the placenta, indicating serious illness ruptured perebіgu vagіtnostі.

When administered intravenously for injections, Atropine can cause intrauterine pathology in the development of the fetus in the mother's womb. In the period of lactation, the faces can be stagnant, but with care, shards of a trace concentration of the speech of the farm can penetrate into breast milk.

Droplets Atropine for children

With extreme caution, you can zastosovuvat Atropin when you are happy with children for 7 years. With cerebral lesions, cerebral palsy and downtime, the drug can, alternatively, improve the reaction of the child's body to drugs of this pharmacological group.

As a drug, it is necessary to fight against children with periodic and chronic diseases of the upper and lower dychal paths, it is necessary to work at the hospital, and we should always look at fakhivtsiv. These recommendations are for the weakened children's ailments. Doctors are responsible for the concentration of bronchial secretions, so as to reduce the increase in density and viscosity, and then blockage of the bronchial passages.

especially vkazіvki

When taking atropine, be it one of the recognized methods, in order to avoid a possible development of tachycardia, you can put a tablet under the tongue. Practical for skin care a number of contraindications- about tse also not a trace to forget.

Even in the period of likuvannya, the patient needs to be taken care of by transport means, otherwise, to increase the concentration of respect, we should be careful with dosing and taking.

Atropine price

Prydbati Atropin in the pharmacy for an additional prescription of the doctor is not a warehouse of special difficulties. So the rest of the hour became incredibly handy to bathe preparations online pharmacies. Such a way to save money and save a lot of time. Price for Atropine It is not a major factor in choosing the method of purchase, since you can get a pack of lika for 40-50 rubles both in the primary pharmacy and on the Internet.