Ketonal cream: instructions from the application. Ketonal ointment

Accessibility, simplicity of victoria and the ability to infuse directly on the site of the infection explain the wide popularity of the drug for external application.

Pharmacological power.

The presence of the drug Ketoprofen at the warehouse allows Ketonal to be classified as a large pharmacotherapeutic group of non-steroidal anti-inflammatory drugs. Behind the chemical structure, the active speech is classified as similar to propionic acid, to that, for the pharmacological powers of Ketonal, it is rich in what is similar to Ibuprofen, but it will overturn yoga for the power of diї.

Ketonal is one of the most powerful analgesics in the line of NPZZ, has a greater analgesic effect, lower codeine-containing drugs (similar to morphine opioids codeine and non-narcotic analgesic analgesic or paracetamol ). The clinical effect of the confusion about the development of Ketoprofen is to ignore the activity of the cyclooxygenase enzyme present in most tissues in the body. This is the key enzyme that transforms arachidonic acid into prostaglandins, as intermediaries and regulators of various physiological processes, incl. igniting reaction and apparently pain.

Why does Ketonal ointment help? Locally in the zone of application, igniting the vibration of various enzymes, which start the pathological process, blocking the biosynthesis of prostaglandins without intermediary damage, which enters the warehouse of the mast form Ketonal Ketoprofen may have such effects:

• anti-flash- Ignore the ignition reaction, shift to a distant development of the ignition process, use the more advanced manifestation. The effect is manifested in low temperature near the fire, hyperemia of the fur coat, sickness and swelling of the snow;
• analgesic- change or more commonly used in peripheral tissues and organs;
• anti-bacteria- lowering the penetration of other veins and capillaries (the result of the infusion of blood vessels and plasma mediators of inflammation), increasing the tone of the vessels, improving metabolism in tissues, changing the process of exiting exudate in the tissues and emptying the body and, as a result, the development of swell ku, zdavlyuvannyu nervovyh zakіnchenyu that polennyu.

Warehouse, release form

Registration officer Ketonal is a multinational pharmaceutical company Sandoz Pharmaceutical, Slovenia. Virobnik company - Salutas Pharma, Nimechchina.

For stoking, two medicinal forms are prescribed, which are released under the Ketonal trademark:

• Gel (25 mg Ketoprofen) - prosorium, homogeneous, light texture. Supplied in 50 or 100 g aluminum tubes. The basis of the gel is carbomers - rare acrylic polymers. Trolamine is used to regulate pH and softness. As an additional ingredient, the gel can be washed: 96% ethyl alcohol - a retailer, non-infective and drying agent, ethereal oliya (lavender). To the given obsyagu to be brought with purified water.
• Cream (50 mg Ketoprofen, also known as Ketonal cream 5%) - white, uniform, oily consistency. Packed in aluminum tubes with a plastic cap that closes. Use tubes of 30, 50 and 100 g. The basis of the cream is medical vaseline oil. The warehouse of the composition also includes: methyl and propyl parahydroxybenzoate - preservatives and antiseptics, propylene glycol and highly purified water - retailers, isopropyl myristate - an emollient that helps soften the skin, Elfacos ST 9, a combination of glyceryl oleate and propylene glycol - emulgil.

Yak de ointment Ketonal

The therapeutic effect of Ketonal for tension can be compared with the effects of strong non-steroidal drugs in the first line in the treatment of subglobular pathologies - Diclofenac, Indomethacin, Naproxen. It flows into the fibers of the peripheral nerves and the body of neurons, spreading in the central nervous system. With this intoxication, Ketonal, a selective COX-1 inhibitor, negatively affects the work of the enzymatic enzyme, which increases the risk of causing various side effects.

Possibility of zastosuvannya Ketoprofen is perfectly safe in this case, the active speech is not able to give an ulcerogenic effect, which is the case in the case of low-grade cells of the mucous membranes of the CT. It is explained by the delivery of Ketoprofen to tissue damage, bypassing the high concentration in the blood.

Yak de Ketonal ointment (gel)

• lowering the sensitivity threshold of peripheral nociceptive closures, which react to threatening ear stimuli and form the basis of pain sensations - a painful effect is felt already after 5-10 minutes at the time of application to the warehouse;
• change the intensity of the pathological process due to the fact that ignoring prostaglandin vibrations, ignoring the activity of the products of the lipoxygenase pathway of the transformation of arachidonic acid and bradykinin - a peptide that mediates smooth muscle tone, what flows into the endothelium of blood vessels;
• stabilizing the existing lysosome membranes, reversing and destroying acid hydrolases, building and degrading organs and tissues;
• it does not interfere with catabolic processes - it does not damage the metabolism of the middle sludge and does not harm the health of hyaline cartilage;
• usuvaє discomfort, stiffness of m'yaziv, skutist' rukhovyh aktiv, tugorukhlivist suglob after trival calm, illness, increase in volume and amplitude of ruhiv repairing a ligament, a tendon or another closed injury of the soft tissue).

Instructions about the onset of clinically significant pharmacokinetic parameters of Ketonal ointment:

• Absorbed by epithelial prostrate. She gets wet and penetrates into the comrades shkiri properly, which will ensure the prolongation of the day.
• Biological availability of the original medicinal form - 5%.
• Hem the upper balls of the skin, dermis, subcutaneous fatty tissue, better penetrate deep tissue and empty. The active speech is concentrated more importantly in the tissue of the sac, the m'yazovo-svyazuvalny apparatus, the synovial nerve - here it is 100 times greater than the plasma concentration. Therapeutic value of Ketoprofen in tissue damage is saved from time to time.
• In the systemic blood circulation, it is consumed in the minimum amount, Ketoprofen is detected in the blood plasma 6 years after the treatment of the tila mazzyu. With bugatoriasis repeated vicarious organisms do not accumulate.
• Under the influence of hepatic enzymes, it is completely biotransformed.
• The end products of metabolism are excreted from the section through nirks. Excreted properly.

Show to reception

The main indication of Ketonal is the use of pain syndrome and the ignition process of various changes and localization, and the progression of the ailment of the veins does not contribute to the cause of the disease. You call the submarine element of therapy to be recognized as a comprehensive pirkhodi to the likovanni of the pathology of the owl of the Schwidko Dupo for the Schwisky Language, the Polivnia of the Functional I will become the pivishchensnik of the prazneshnika to the moment of the animal to the likar.

Drugs Ketoprofen, indicated for oral, parenteral aborectal administration, may have a wide range of applications. The medicinal forms of Ketonal are used for headaches and monthly pains, migraines, phlebitis, lymphangitis, oncological and gynecological diseases.

Ketonal - it helps a lot: according to the instructions, the cream or the gel vikoristovuetsya more importantly in case of damage to the bone-loam apparatus or the m'yazovy system.

Tse takі zahvoryuvannya abo timchasі become:

Installation instructions

Different types of medicine Ketonal, the dose of Ketoprofen and the regimen for taking are selected depending on the nature of the disease, the severity of the pain syndrome and the area of ​​the scales, which will require processing. The rules for applying cream and gel are similar. But it is important to note that, as prescribed in the official instructions for zastosuvannya, Ketonal cream to avenge a large dose of Ketoprofen and properly swear, characterized by a prolonged depletion. The gel evenly lays, has a good penetrating property, easily wields Ketoprofen, which can be avenged in the dark, and swidshe dіє.

For greater effectiveness, the oral form of Ketonal can be taken with systemic drugs - tablets, injections with candles. When it is necessary to control the total amount of additional dosing of Ketoprofen that enters the body, it is not guilty to overdosing 200 mg. At the time of passing the hour of the devil's reception, it is not possible to win the dose. In order not to increase the concentration of active speech in the blood and reduce the risk of systemic side effects, independently (without the doctor's recognition) increase the dose or continue the treatment.

• Clean up well (possibly with additional vicarious antiseptics) that dried surface of the shkiri, uniquely mіsts іz broken tsіlіsnіstyu shіrіkіr curve – opіkovih, wounded, іnfіkovanіh dіlyanok. Take care of the eyes, that the area of ​​that іnshі mucus membranes lies before them, as particles of ointment get on them.
• Apply in the area of ​​maximum sickness directly above the pathological center. Rozpodіlyat with a thin ball, neat, soft and rough, which you rub, checking for a new warehouse.
• A single dose is 3-5 cm stovpchik cream chi gel. Multiplicity of zastosuvannya - 1-3 times a day.
• The maximum validity of the exchange rate is 2 tyzhn.
• It is not recommended to wrap the area with a non-permeable material.
• After the completion of the jubilant session, thoroughly wash your hands under running water.

No overdoses of overdosage with ovnishnimi forms of ketonal were detected. When an allergic reaction is revealed, the area should be washed with a large volume of water and taken with liquid. Advance care is needed for patients with impaired labor, liver, heart failure, ailments of the PCT, blood system, bronchial asthma.

Read about: cause that yak kuvati to appear.

Instructions for congestion apply Ketonal ointment in case of different manifestations:

• individual intolerance to the warehouse medicine, Ketoprofen or other NPZZ;
• aspirin triad;
• reactions of medicinal photosensitivity;
• the rest trimester of pregnancy, breast fertility;
• child age - 0-12 years (12-15 years - under the control of the doctor).

Side effects

Ointment Ketonal is well tolerated, there are no serious side effects.

In lonely moods, a mischievous reaction may develop, to which it can be seen:

• reddening, peeling, sharp liver, sverbіzh shkіri;
• kropiv'yanu lihomanka, different in appearance, that form hanging;
• eczema, otherwise the fuse of the surface balls of the skin;
• Stevens-Johnson syndrome;
• tissue necrosis;
• increased sensitivity to ultraviolet.

Respect!

In order to get rid of the possible transcendental reaction of the shkir to the sleepy light, for a long period of relaxation and even 14 days after the completion of the therapeutic course, it is recommended ї fabrics). Instructions for consolidating Ketonal ointment with other conventional forms, based on NPZZ. It is necessary to protect the health of Ketonal and increase the toxicity of Methotrexate. Patients who take in parallel the protection against coumarin are guilty of being constantly guarded by a doctor. About other significant medical interactions, the instructions are not ahead.

Varity of the drug, analogues

Pharmacies dispense Ketonal ointment without presenting a prescription. Take care of the medication at the factory container, at a clogged look, at a temperature that does not exceed 25 degrees. For such minds, the choice of terms of attachment to the gel is 3 years, to the cream - 5 years.

Average varity of packaging stock:

• gel 2.5% 50 g - 345 rubles, 100 g - 465 rubles.
• cream 5% 30 g - 320 rubles, 50 g - 420 rubles, 100 g - 585 rubles.

You can replace it with topical forms, which can avenge the same active speech, or else they are released under other brands.

Finding analogues of Ketonal ointment:

• Ketoprofen;
• Bistrumgel;
• Febrofid;
• Fastum;
• Valusal;
• artrosilene;
• Pentalgin Extra-gel.

Before taking any drug to avenge the NPZZ, it is necessary to consult with the doctor in advance, or respectfully read the instructions to turn on the presence of contraindications, learn about the rules for accepting and recognizing about safe dosing.

additional speech: methyl parahydroxybenzoate - 2 mg, propyl parahydroxybenzoate - 0.5 mg, propylene glycol - 70 mg, isopropyl myristate - 50 mg, vaseline white - 320 mg, elfacos ST9 - 30 mg, propylene glycol glyceryl oleate. mg.

30 g - aluminum tubes (1) - packs of cardboard.
50 g - aluminum tubes (1) - packs of cardboard.

Pharmacological activity

NPZZ. May analgesic, protizapalnu and protinabryakova diyu. Ignore the activity of COX, which leads to the inhibition of the synthesis of prostaglandins. In addition, ketoprofen inhibits lipooxygenase, synthesis of bradykinin, stabilizes lysosomal membranes and changes the viability of enzymes, which take part in the ignition process.

Ketoprofen is not injected into the cartilage camp.

Pharmacokinetics

Vsmoktuvannya

Ketoprofen gets wet even though it practically does not accumulate in the body. Bioavailability to become 5%.

Ketoprofen penetrates into the subcutaneous tissue, bonds and mucus, the synovial cavity and reaches therapeutic concentrations there. The concentration of the drug in the blood is very low.

Metabolism and vision

Ketoprofen is metabolized in the liver to the approved conjugates, which are mainly excreted in the cross section. Ketoprofen is characterized by frequent withdrawal from the section.

Pharmacokinetics in specific clinical situations

Metabolism of ketoprofen does not lie in the eye, the manifestation of severe or cirrhosis of the liver.

Indication

Symptomatic therapy of ailing and igniting processes of various genesis, incl.

- rheumatoid arthritis and periarthritis;

- Ankylosing spondylitis (Bekhterev's disease);

- Psoriatic arthritis;

- Reactive arthritis (Reiter's syndrome);

- Osteoarthritis of different localization;

- Tendinitis, bursitis;

- Mialgiya;

- Neuralgia;

- Radiculitis;

- injuries of the musculoskeletal apparatus (including sports ones), clogging of the tongue and ligament, stretching of the ligament, tearing of the ligament and tendon of the tongue.

Contraindication

- Increased sensitivity to the components of the drug;

- increased susceptibility to salicylates, thiaprofenic acid and other refineries, to fenofibrate, UV-promenade blockers, breathers;

- Destruction of the integrity of the skin folds (eczema, weeping dermatitis, open or infected wound);

- History of history of attacks of bronchial asthma, previous use of NSAIDs and salicylates;

- Photosensitivity reactions in history;

- Infusion of sony light, incl. indirect sony exchange and UV exposure in a solarium for a long period of lubrication and 2 days after the lubrication;

- III trimester of pregnancy;

- Child age up to 15 years.

With care: impaired liver and/or liver function, erosive-virazkove lesion of CT, blood poisoning, bronchial asthma, chronic insufficiency.

Dosing

For zovnіshny zastosuvannya.

A small amount of cream (approximately 3-5 cm) with light hands, which is rubbed, applied with a thin ball on the skin over the wound. Apply the cream 2-3 times per doba.

Trivality of jubilation without consulting a doctor is not guilty of revisiting 14 days.

Pobichna diya

Mistic reactions are most often blamed.

The frequency of adverse reactions was determined: very often (≥1/10), often (≥1/100 and<1/10), нечасто (≥1/1000 и<1/100), редко (≥1/10 000 и <1/1000), очень редко (<10 000).

Allergic reactions: more rarely - angioedema, anaphylaxis.

From the side of the shkiri and the shkirnih appendages: infrequently - erythema, sverbіzh, liver, eczema, transient dermatitis of mild severity; rarely - kropivyanka, visipannya, photosensitivity, bullous dermatitis, purpura, bagatoform erythema, lichenoid dermatitis, skin necrosis, Stevens-Johnson syndrome; more rarely - a single episode of severe contact dermatitis (on aphids of nasty hygiene and insolation), a single episode of severe generalized photodermatitis, toxic epidermal necrolysis.

From the side of the dichal system: more rarely - asthmatic attacks (as a variant of an allergic reaction).

From the side of the sieve system: even more rarely - deterioration in the function of nirok in patients with chronic nirkovoy insufficiency.

Overdose

Symptoms: rozdratuvannya, erythema, sverbіzh.

Likuvannya: follow the prescription of the drug. The patient needs to turn to the doctor.

Medical interaction

Although plasma concentrations of the drug are extremely low, symptoms of interactions with other drugs (similar to those in systemic congestion) may be less likely with frequent congestion.

One-hour administration of a change in the degree of binding of ketoprofen to plasma proteins.

Ketoprofen reduces the incidence of methotrexate and increases its toxicity.

Interaction with other medical care and influx on their appearance is not significant.

Patients who take coumarin anti-thrombotic preparations are recommended to undergo treatment under the supervision of a doctor.

especially vkazіvki

It is necessary to apply the cream in the eyes, on the skin around the eyes, mucous membranes.

If any side effects appear, it is necessary to take the drug and turn to the doctor.

If a patient forgets to forget the cream, then he will beat it up at that hour, if an offensive dose can be applied, but do not fight it.

Cream for healthy zastosuvannya can be zastosovuvaty with other drug forms of the drug Ketonal (capsules, tablets, suppositories). The total supplementary dose, regardless of the medicinal form, is not guilty of overdosing 200 mg.

With the appearance of shkirnih reactions, zokrema. yakі rozvinulis with total zastosuvanni z octocrylene-containing drugs, followed negligently pripinit likuvannya.

In order to reduce the risk of photosensitivity, it is recommended to protect the skins with a cream with a cloth in the UVI for a long period of lubrication and for another 2 days after applying the gel.

Likarsky antizapalny zasib from the group of non-steroids.

Price view 298 rub.

Likarsky antizapalny zasib from the group of non-steroids.

Zastosuvannya- Likuvannya (symptomatically) incendiary illnesses of a different hike

Analogues- Fastum gel, Artrozilen, Bistrumgel.

Today we tell about the cream "Ketonal". In some cases, zastosovuyut, what are the counter-indications and side effects of maє likarsky zasib? Analogues of the drug "Ketonal" cream. Instructions for zastosuvannya.

What is the cream

Ketonal is included in the NPZZ group. The drug is zastosovuyut in case of fractures, clogged muscles, igniting ailments of loam. The cream relieves heat and inflammation, may cause pain relief.

Cream Ketonal may look like a uniform mass of white color.

Active speech

(3-benzoyl-alpha-methylbenzoic acid). It belongs to the group of non-steroidal drugs and can be added to similar propionic acid.

Ketoprofen relieves inflammation and pain. Speech is similar in its pharmacological powers to ibuprofen.

Cream warehouse

Golovna rechovina in cream Ketonal -. The concentration of їх in the cream becomes 5%. 1 g of cream contains 50 mg of ketoprofen.

The warehouse of Ketonal includes additional components (for 1 g of cream):

Let’s understand why Ketonal and Ketoprofen are different: Ketonal is the name of the jubilant, and Ketoprofen is the head of the tongue.

Release form and packaging

The drug Ketonal is released in the form of:

• tablets;
• candle;
• rozchin for injections.

Ketonal cream is dispensed in aluminum tubes with a volume of 30, 50 and 100 g, packaged in a cardboard box.

Pharmacological activity

Ketoprofen can have such an impact on the body:

• antipyretic;
• pain reliever;
• antibryakovy.

Ketoprofen inhibits cyclooxygenase, least of all lipoxygenase. In conjunction with cym, the synthesis of prostaglandins and bradykinin is inhibited. Stabilization of lysosomal membranes is observed.

Speech is not bad for suglobovim cartilage.

Pharmacokinetics

Vsmoktuvannya

Ketoprofen is injected into the tendons, mucus, and loamy tissues, penetrates into the deep loamy area, and concentrates until a liquor effect is reached. In plasma, ketoprofen practically does not accumulate.

Speech does not have much strength infusion at distant zastosuvannya. Bioavailability to become less than 5%.

Diya speechovina lie in vіd vіku people.

Metabolism and vision

The processes of disintegration and exchange of ketoprofen are carried out in the oven, speech is produced from the cut of the trival hour.

Pharmacokinetics in a few clinical cases

In patients with liver failure, accumulation of speech in the tissues of the body is observed.

In case of lack of speech, trochs are more pronounced, lower sound.

In older people, the metabolism and administration of the drug is improved, but it may be less important if the functioning of the drugs is impaired.

Indication before whisking cream

Indications before the recognition of Ketonal є igniting the process of various trips:

• neuralgia;
• bursy;
• lumbago;
• arthritis - psoriatic, reactive, rheumatoid;
• pain in m'yazakh;
• ishias;
• ankylosing spondylitis (chronic disease of the subarachnoid ridge);
• osteoarthritis.

Also, Ketonal cream is used to treat injuries of the musculoskeletal apparatus:

• open the ligament and tendon;
• zabittya m'yazіv that zv'yazok;
• stretching the bells.

Instructions from zastosuvannya and method of vikoristannya

Use the cream to cover the ailments of the body, easily rub it on the skin with circular ruhs.

Chi does not impose a hermetic bandage on the cream.

Dosing

Without the recognition of a doctor, the cream cannot be beaten for more than two types.

For doba, a dose of 0.2 g of ketoprofen is allowed.

Respect! If other forms of ketoprofen drugs are taken at the same time as the cream, the additional dose is also not guilty of being more than allowed.

In the case of a woman with a cream with a thickness of 5 cm, 100 mg of ketoprofen should be taken. At one time, you can vicorate 50 mg of the drug, 3-4 times a day.

With a large area of ​​inflammation, you can apply 100 mg of ketoprofen two per day.

At the time of skipping the chergovy application of the cream of the offensive, the amount of time is not necessary, and the cream is applied at the greatest obsya.

In domestic minds, Ketonal is allowed to stagnate at the sight of a difference for injections (in / m). Іn'єktsiї vykonuyut 1-2 times a day for 100 mg of the drug (together one ampoules in 2 ml).

If Ketonal cannot be stagnant

Cream Ketonal zastosovuyut with caution, looking at the contraindications:

• child age up to 12 years;
• Virazkovy ill SHKT, especially at the stage of zagostrennya;
• low pharynx;
• a history of allergic reactions to NSAIDs (bronchospasm);
• heart, nirkova and liver failure;
• vіdkritі rani on shkirі;
• the remaining trimester of pregnancy;
• suspicion of internal bleeding;
• postoperative period, especially after coronary artery bypass grafting

Pobichna diya

Most often, patients have allergic reactions to skins in the areas of application - sverbizh, kropiv'yanka, chervoninnya.

Side effects of Ketonal can be used in case of overdose.

Allergic reactions

Sverbіzh, hanging, kropiv'yanka; rіdshe - allergic, zadyshka, bronchospasm. Possible angioedema, anaphylactoid reactions.

Sechovidilna system

One by one, there were signs of impaired liver function and nephritis. With a 3-valued total intake of NPZZ and sechoginic diseases, hematuria is possible.

Dermatological reactions

In three out of a hundred patients, there are negative effects of Ketonal stagnation from the side of the shkir. Tse chervoninnya, kropivyanka, weakly expressed dermatitis.

Vіdomi 2 types of dermatitis - the one of generalization.

Dyhalna system

Rarely - an attack of asthma and bronchospasm, as if manifesting allergies.

Stasis with vagity and breastfeeding

Ketonal is prescribed for vaccination in the first six months, evaluating the possibility of influx into the pregnancy. In the rest of the month, the cream with ketoprofen does not please the doctor.

Zastosuvannya at the child's vіtsi

Children under 12 years of age are not prescribed Ketonal.

In the event of teasing, viscidity, or other manifestations of negative symptoms, the drug should be administered.

Be careful not to get the cream in the right place, eyes and mucous membranes.

When vikoristannі cream can not be smeared, the next uniqueness of ultraviolet prominennia. After the completion of the exchange rate, two more it is necessary to unify the direct sleep exchanges and the Ural Federal District.

After applying the cream, wash your hands with sweetness.

Having poured into the building keruvati by mechanisms and transport means of not twisting.

Important! The combination of Ketonal and alcohol is unacceptable: there is a risk of bleeding, alcohol is causing side effects of the drug problem.

Zastosuvannya with damaged functions of the liver and liver

Ketonal in the cream does not directly affect the functioning of the liver and liver.

Obov'yazkovo control arterial pressure and indications of the functions of organs.

In case of liver insufficiency and nirok, the drug was taken before zastosuvannya.

Overdose

In case of severe congestion, an overdose of the drug was not suspected.

Possible symptoms are:

• chervoninnya;
• hanging.

At the same time, the maid suffered to miyut with water with a sweet one, and rinse it with water under the tap.

Symptoms of overdose with internal Ketonal intake

When taking the tablet form of the drug and overdosing, the following symptoms are observed:

• boredom;
• vomiting, possibly, vomiting with blood clots;
• bіl in the stomach;
• confusion of information;
• difficulty breathing;
• disruption of the functioning of nirok;
• nir's deficiency.

Likuvannya in case of overdose

There is no special antidote.

Likuvannya to be carried out in the coming rank:

• wash the hose;
• assign actives to vugillya;
• blockers of H2-histamine receptors (Ranitidine, Famotidine);
• prescribe proton pump blockers and prostaglandins (omeprazole).

Interaction with others

It is not possible to take other ointments, gels and creams of the non-steroidal group or to avenge ketoprofen from the zastosuvannyam cream "Ketonal" at once.

Ketoprofen improves the use of methotrexate and potentiates its toxicity.

The use of acetylsalicylic acid and concomitant use of Ketonal with vicarious drugs reduces the binding of ketoprofen to plasma proteins.

Interaction with other medical care is insignificant.

Preparation material specially for the site site edited by clinical pharmacologist Nedelko K.V.

. Gel, oral cavity - ketoprofen, 1 g of the drug 25 mg ketoprofen. Reduced concentration of the gel is effective for mild pain.

. Speech ingestion - ketoprofen lysine strength, in 1 g I will take 25 mg of active speech.

Analogues of Ketonal Fastum-gel, Bistrumgel, Artrozilen should not be inaccurate in the price of the original.

The cheapest option is ketoprofen, but after the injection on the body, it does not look like expensive preparations with strong speech ketoprofen. The list of indications is the counter-indication of the same one that Ketonalu has. Vygіdna vіdminnіst is a preparation from the pretreatment of precautionary permissions until the zastosuvannya for children at the age of 6 years.

Ketonal cream - zasіb for zovnіshny zastosuvannya, which can protizapalnuyu diyu, suvaє swollen and ill-natured. Vіn indications for chronic illnesses and first aid in case of clogged areas and injuries. The drug is mittevo anesthetic and reduces the severity of the rukhakh. At the same time, you know that the Ketonal ointment is now victorious and it’s right to vicorist.

Release form

Ketonal is available in several dosage forms:

• Ketonal 5% cream is a drug for cold soreness, which is used to reduce pain and inflammation in the m'yazah and snowdrifts. Zasib may have had a uniform consistency. Packed in tubes of 30, 50 and 100 g.
• Gel Ketonal 2.5% - zasіb for medical zastosuvannya with pain in the m'yazah and swamps. The preparation has a homogeneous texture to the gap. It is produced in tubes of 50 and 100 g.
• Ketonal tablets - 100 mg of ketoprofen is contained in 1 tablet coated with a plaited shell. It is prescribed for symptomatic relief of pain and igniting processes of various walks.
• Plastir Ketonal Thermo is a plaster that rozіgіvaє, a kind of relaxing m'yazi, bring relief from pain in the back and shoulders.
• Ketonal pricks - rozchin for injections in ampoules 2 ml, concentration 0.05 / ml. It is prescribed for internal and internal introduction.
• Capsules Ketonal Duo with modifications to vilnennyam 150 mg per 1 capsule. Two forms of pellets ensure step by step development of active speech, at the same time a quick and prolonging effect.

Pharmacodynamics

Mechanism of directing ketoprofen to reduce sensitivity to painful sensations due to blockage of receptors. Vіn galmuє utvochennya prostaglandin and bradykina, which stimulate the development of the ignition process.

Ketonal seals the walls of the vessels, reduces their penetration and removes folds, redistributes the blood in the chest blocking the release of platelets.

Ketoprofen does not change the structure of the cartilaginous tissue for other anti-inflammatory drugs, it increases the tightness of the folds and the easier roughness of the loam.

Pharmacokinetics

Ketonal ointment in a small amount gets wet in the bloodstream and practically does not accumulate in the body. The good penetrating quality of active speech through the skinny covering and the innermost cell wall helps to reach the m'yazovoi tissue, suglobiev, ligamentous apparatus.

Ketoprofen is combined with proteins in the liver and is gradually removed from the section.

Zavdyaki tsim authorities the drug lasts for an hour in the area of ​​application, ahead of the development of side effects.

Indication before zastosuvannya

Zastosuvannya Ketonal quickly absorbs bіl, ahead of the aggravation of that ignition process. Trim your anti-sap zasib with your hand in the first-aid kit.

In case of indications before zastosuvannya ointment Ketonal so become:

• Arthritis (rheumatoid, psoriatic, reactive, periartitis);
• Relief of pain syndrome in m'yazah and swamps;
• Injury and clogging of the musculoskeletal apparatus;
• Raztyaguvannya that razryvi zv'yazok, tendon;
• Osteoarthritis;
• neuralgia;
• Radiculitis.

Contraindication

The first step is to try the drug, including contraindications:

1. Vagity in the third trimester;
2. It is not possible to win for children up to 15 years old;
3. In case of individual intolerance to the warehouse drug Ketonal;
4. In case of damaged integrity of the skin covering and in case of skin diseases;
5. Attack bronchial asthma caused by salicylates and non-steroidal anti-inflammatory drugs;
6. With increased sensitivity of the shkir;
7. Direct injection of ultraviolet changes, including solarium.

Important! To protect people from chronic and hospitable ailments of nirok, liver, and viral processes in the intestinal tract.

The video of the drug tells about the drug Ketonal, the course of treatment, side effects and analogues:

With vagity and lactation

In the first trimester and the other trimester, ointments are allowed. In this case, the drug is prescribed only as a medicine, which improves the risk for the health of the fetus from the woman's camp.

If it is necessary to recognize the child during lactation, pinch the baby to the breast, and transfer the child to the sum.

Pobichna diya

The side effects caused by the vicarious drug are most often blamed for individual intolerance to the components in the warehouse. The stench is manifested by the symptoms of an allergic reaction: redness, overthrown, liver, droppings in the area of ​​application.

Overdose

There is no information about cases of overdosing with ketonal when the drug is ingested.

An overdose of oral and injectable drugs may be accompanied by the following symptoms:

• entanglement of information;
• Difficulty breathing;
• Nudota;
• Vomiting, including vomiting of blood clots;
• Bіl in the stomach;
• Nir's deficiency;
• Destruction of robotics.

There is no specific antidote for Ketonal overdose. It is prescribed symptomatically.

Medical interaction

Apply the Ketonal cream at once, using medical methods, to avoid ketoprofen. It is not recommended in conjunction with other forms of non-steroidal anti-inflammatory drugs for healthy constipation.

Ketoprofen reduces the incidence of methotrexate and increases its toxicity to the body.

Taking acetylsalicylic acid reduces the binding of ketoprofen to plasma proteins.

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The main component of Ketonal is ketoprofen.

Pharmacological power of ketoprofen:

• Usuvaє igniters;
• Knowing swelling;
• Pain.

Ketoprofen, penetrating into the depths of the skin's curve, suppresses the synthesis of components, which induces the ignition process. For the lowering of the vibrations of these speeches, that scorched inflamedness is known.

The active warehouse does not indicate functional or structural damage to the loamy cartilage. The drug is fully absorbed from the skin and cartilage tissue, so it accumulates in the body in a small amount. An insignificant amount of ketoprofen accumulates in m'yazah, zv'yazkakh, pіdshkirny ball and synovial rіdinі, reaching optimal therapeutic doses. Plasma concentrations of ketoprofen are low.

The cream of the main component, before the warehouse of the medicinal form, additional speeches are included, in order to improve the penetration of assets and to win the additions of power:

• Vaseline;
• propylene glycol glyceryl oleate;
• propylene glycol;
• Isopropyl myristate;
• Magnesium sulfate;
• Elfakos ST9;
• Methyl parahydroxybenzoate;
• Propylparahydroxybenzoate;
• Purified water.

Skіlki koshtuє?

The price of Ketonal in the form of a cream is approximately 110 rubles per tube of 30 grams.

A tube of Ketonal with a volume of 50 g will cost 350 - 400 rubles.

What is better than Ketonal gel chi cream?

Cream and gel to avenge one and the same fluffy speech, but the difference between them is.

Indications for cream or gel Ketonal have a consistency in the preparation. The gel miraculously penetrates into the deep corner of the skin behind the shell of active conductors, which are located at the warehouse. Tse give zmogu zbіshiti trivalіst dії drug. The medicinal value of the form of the cream is more often spread on the skin curve and it can be twisted for massage.

Installation instructions

Before using the cream, it is necessary to read the instructions and change the contraindication. It is recommended to go back to fakhivtsya, which will help you to set the course of likuvannya.

Instructions for zastosuvanya Ketonal:

1. Apply as needed on a clean and dry skin;
2. Whisk a small portion - enough pea cream for a suglob;
3. Apply the drug on the epidermis of the inflamed and painful area;
4. Rub the portion with light massage rubs;
5. Vykoristovyte zasіb vіd 2 to 3 times per day;
6. Trivality to the course of healing should follow the doctor;
7. The trivality of the jubilation of the mazzyu is not guilty of revisiting the 2 tyzhn ​​without recognition of the doctor.

especially vkazіvki

• Uniquely used ointment on mucous membranes;
• Can be combined with other medicinal forms of strengthening therapeutic action;
• Do not overdosing, if you forgot to apply the drug every hour, skip this time and apply the next time;
• With the appearance of side effects, or teasing on the skin's cover, attach glee and turn to the doctor;
• To prevent the photo-sensitivity of the shkiri, it is recommended to wear a closed garment, protecting the area of ​​application with it;
• After victorious ointment, gently shake your hands in order to avoid teasing the skin's curve and mucous membranes.

Analogues

Іsnuyut analogues of Ketonal of venison and foreign production. Similar preparations are on sale, in the basis of which there is an identical infective speech, or they are similar to pharmacological authorities. Find out from the doctor how you can replace Ketonal.

Artrosilene Gel

• May be analgesic, anti-inflammatory, antipyretic;
• Ignore the vibration of ignition components in the body;
• Usuvaє swollen suglobіv and zbіshuє rukhovu activity;
• It is recommended to use vicorist for pains of the musculoskeletal apparatus, for rheumatic diseases, for injuries and clogged muscles, as well as for flare-ups in the snow, m'yazah and tendons.

Variation: 420 rub.

Fastum gel

• Maє nebolyuvalnu diyu;
• Knowing the burning;
• It is recommended to vicorate in case of injuries of m'yazіv and zv'yazok;
• Effective in igniting processes of acute and chronic type;
• Plivaє shvidko and usuvaє bіl;
• Do not fill up the tracks on the odes.

Variation: 270 rub.

Bistrumgel

• May analgesic diyu and usuvaє inflamed;
• Effective in traumatic injuries of the musculoskeletal apparatus;
• The formulation contains the active ingredient ketoprofen;
• It is necessary to apply with a thin ball.

Variation: 230 rub.

Ketonal has cheaper analogues: Ketoprofen, Flamax, Artrum.

Instructions for zastosuvanya Ketonal
Buy Ketonal cream 5% 50g
Medical Forms
cream for healthy congestion 5%
Virobniki
Lik d.d. (Slovenia), Salyutas Pharma GmbH (Nimechchina)
group
Anti-seizure drugs - poisons of propionic acid
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Active speech - ketoprofen.
International non-proprietary name
Ketoprofen
Synonyms
Arketal Rompharm, Artrozilen, Artrum, Bistrumgel, Bistrumcaps, Valusal, Ketonal Duo, Ketoprofen, Ketoprofen MV, Ketoprofen Organic, Ketoprofen-Verte, Ketoprofen-Vramed, Oki, Fastum, Febrofid, Flamax, Flamax
Pharmacological activity
Antiseptic, analgesic, antipyretic, antiaggregatory. May have anti-bradykinin activity, stabilize lysosomal membranes and inhibit the development of enzymes from them, which will help to absorb the destruction of tissues in chronic inflammation. When introduced internally, it is wetted to milk again. Absorption is accompanied by the effect of "first pass" through the liver. The concentration in the blood is dose-dependent. It is easy to pass through histohematic barriers and rozpodіlyaєtsya in tissues and organs. Biotransformation in the liver (practically more). Metabolism is excreted from the section. Changes the rank scootiness and swelling of the loams, increasing the swelling.
Indication before zastosuvannya
Rheumatoid arthritis, non-specific spondyloarthritis (ankylosing and psoriatic spondylitis), pain syndrome (postoperative, post-traumatic pain, pain with bone metastases), gouty arthritis, pseudogout, osteoarthrosis, post-surgical rheumatism and menorrhea. Gel - uncomplicated injuries (stretch marks and rupture of the tendon and ligaments, clogged m'yazіv, bruises).
Contraindication
Hypersensitivity, nirkova and liver insufficiency, dyspepsia and duodenal ulcer in the acute phase, "aspirin" asthma, vaginess and childish age. Candles - proctitis and proctorrhagia; Gel - dermatosis, eczema, infections of the garden and wounds (moist).
Pobichna diya
Headache, constipation, noise in the ears, drowsiness, weakness, sickness, dyspeptic symptoms (nausea, vomiting, abdominal pain, diarrhea, flatulence, constipation, anorexia), stomatitis, impaired liver function, hyperemia, allergic re shares.
Interaction
Suggested toxicity to methotrexate. Plasma concentrations of ketoprofen increase against the background of probenecid (ignoring nirk excretion). Substance effect of anticoagulants, heparin, ticlopidine, corticosteroids, oral anti-diabetic effects and alcohol, mild effect of spironolactone, peripheral vasodilators.
Method of stoking and dosing
Zovnishno, apply the cream with a thin ball over the center of the fire 3-4 times on the doba, then gently rub it gently. Trivality to the exchange rate is more than 14 days.
Overdose
No data.
especially vkazіvki
Taking ketoprofen may mask the signs of an infectious disease. When the function of the liver is damaged, it is necessary to reduce the dose and more carefully. It is not possible to allow the gel to get on the mucous membranes of the veins. From the protection of zastosovuvat pіd hour of work to the waters of transport zabіv that to people, the profession of which is due to the increased concentration of respect. For an hour of rejoicing, the next step is to take alcohol infusions. In patients with bronchial asthma or allergic diathesis, Ketoprofen can cause bronchospasm.
Wash away the savings
At room temperature in a sheltered light and inaccessible to children.