Leprosy chi leprosy. What is this sickness? Lіkuvannya leprosy and first signs of ailment What is leprosy?

This is a systemic infectious process with chronic overflow, which is caused by leprosy mycobacteria and is accompanied by epidermal, visceral manifestations, as well as signs of damage to the nervous system. There are 4 clinical forms of leprosy: lepromatous, tuberculoid, undifferentiated, and pericardial. The typical signs of leprosy are skin manifestations (erythematous-pigmented patches, bumps, humps), polyneuritis, sharp deformity and appearance, endings and other. The diagnosis of leprosy was made with a lepromin test, bacterioscopy and pathohistological follow-up. Treatment of leprosy is carried out by repeated courses of antileprosy preparations.

ICD-10

A30 Leprosy [Gansen's disease]

Zagalni vіdomostі

Leprosy (leprosy, Hansen's disease) is a low-contagious infection that can lead to generalized granulomatous damage to the curved tissues, peripheral nerves, in important cases - the cystic-mucosal system, eyes and internal organs. Leprosy is considered one of the most ancient ills of the people, like a long run of riches, it instilled a sinister zhah. In the Middle Ages, “lepers” were deafened “died alive”, were ostracized by chivalrous isolation in specialized lichens - leper colonies. Today, the situation before the illness has changed, but, regardless of the availability of a specific treatment, the problem of falling ill with leprosy is no longer relevant for the low lands of Asia, Africa, Latin America. For various tributes, in the world, 3 to 12-15 million people are sick with leprosy; widely diagnosed over 500-800 thousand. new vipadkіv ill.

Cause lepri

Sick people act as leprosy infections, as they see health workers with nasal mucus, spit, breast milk, our homeland, cross section, fecal masses, that leprosy shkiri are cremated. Also, natural reservoirs of infection can be creatures - armadillos and mavpi. Infection with leprosy mycobacteria is most likely to be covered with a mottled path, more often - with a slight skin curve or coma bites. Described the incidence of infection when tattooed.

Leprosy is respected by a slightly contagious ailment; ring the infection before regular and trivaly contact from sickness. Healthy people may have high natural resistance to leprosy. Children are more susceptible to leprosy infection, as well as individuals who suffer from chronic intercurrent illness, alcoholism, drug addiction. The validity of the incubation period has not been established; according to the data of various authors, it can become from 2-3 months to 20 and more years (for the average 3-7 years).

Classification

Vydpovidno to zagalnopriynyatoy klassifikatsii, see 4 main clinical types of leprosy: lepromatous, tuberculoid, non-differentiation and near-cordon (dimorphic). Undifferentiated leprosy is considered an early manifestation of illness, from which two polar clinical and immunological variants develop - lepromatous or tuberculoid. The most malignant type - lepromatous leprosy is characterized by the presence of large numbers of mycobacteria in the body and the negative nature of the lepromine test. In case of a similarly accommodating, tuberculoid type of leprosy, now, in May, the amount of the alarm is small and positive lepromin reaction.

The protyazh of skin s variants of leprosy are indicated as stationary, progressive, regressive and that residual stage. The first two stages are characterized by leprous reactions - aggravated follicles of illness, regardless of the therapy that is being carried out.

Symptoms of lepri

Lepromatous leprosy

The most unacceptable clinical variant of leprosy, which occurs with generalized lesions of the skin, mucous membranes, eyes, peripheral nerves, lymph nodes, internal organs. Shkirny syndrome is characterized by the presence of symmetrical erythematous patches on the faces, hands, front shoulders, gomels, and seats. A heart of stink is filled with a scarlet color, a rounded or oval shape, a smooth gleaming surface, a brown-rusty color swells like a year. After a month, the rocks of the shkir in the area of ​​their visips will be narrowed, and the elements themselves will turn into infiltrates and humps (lepromi).

In the area of ​​infiltration of the skin, there is a bluish-brown color, increased greasiness, enlarged pores. Sweating in the affected areas of the skin decreases, then it reappears. Appreciation of the appearance of brіv, vіy, beard, vusіv. Diffuse inflіltrativnі zmіni lead to the destruction of natural wrinkle and folds of the skin of the face, drooping of the nose, superciliary and temporal arches, broken mimicry, which is why the face of the ailing leprosy is cast and looks fierce leva"). Already at the early stages in the infiltrative follicles, leprosy are established - painless humps with a size of 1-2 mm to 2-3 cm, like rotting hypodermally or dermally.

On the smooth glossy surface of the leprosy, there can be trees of peeling skins, telangiectasia. For the presence of the glee, the leprosy bow their heads; zagojnnya virazok vіdbuvaєtsya trivalo z utavlennyam keloid scar. The skin of the inguinal depressions, the ulna, the sub-knee, the inguinal regions, the scalp is not affected.

With lepromatous leprosy, the pathological process often results in the development of conjunctivitis, episcleritis, keratitis, iridocyclitis. Typical blockage of the mucus membrane of the empty mouth, larynx, tongue, vermilion oblyamіvki lips and especially the mucosa of the nose. In the rest of the fall, nosebleeds, rhinitis are blamed; nadali - infiltration and lepromy. With the development of leprosy in the area of ​​the cartilaginous septum of the nose, there may be perforation and deformity of the nose. Injuries of the larynx and trachea in lepromatous type of leprosy can lead to voice damage right up to aphonia, stenosis of the vocal cord. Visceral lesions are represented by chronic hepatitis, prostatitis, urethritis, orchitis and orchiepidimitis, nephritis. Achieving a specific process of the peripheral nervous system proceeds with a type of symmetrical polyneuritis. With leprosy, derangements of sensitivity, trophic and rukhovy damage develop (paresis of mimic muscles, contracture, trophic viraz, mutilation, atrophy of sweat and sebaceous deposits).

Techniques of lepromatous leprosy of power and periodic flare-ups (lepromatous reactions), when there are times when there is an increase in leprosy, the adoption of new elements, lihomania, polylymphadenitis.

Tuberculoid leprosy

Tuberculoid type of leprosy occurs more benignly with lesions of the scalp and peripheral nerves. Dermatological signs are characterized by hypochromic and erythematous patches with clear contours on the coat, coat, and upper tips. On the periphery of the patches, there are flat slit papules of a reddish-violet color, which predict red flat lichen. Angry among themselves, the papules form plaques of a ring-like configuration (figurative tuberculoid), at the center of which there is a patch of depigmentation and atrophy. The functions of sweat and sebaceous furrows decrease, dryness and hyperkeratosis develop, and vellus hair falls out. With tuberculoid leprosy, nails are often affected, they become dark gray, sweaty, deformed, fragile.

As a result, damage to the peripheral nerves of leprosy is accompanied by impaired temperature, tactile and pain sensitivity. Most often, the lesions of the facial, promeneval, and small milky nerves are sharpened: the stench is emaciated, it becomes painful and palpable. As a result of pathological changes in the peripheral nerves, there are paresis and paralysis, atrophy of the muscles, trophic bends of the feet, contractures (“claw-like hand”, “seal foot”). In neglected depressions, resorption of the phalanges and shortening (mutilation) of the hands and feet may occur. Internal organs in tuberculoid leprosy, as a rule, are not affected.

Undifferentiated that pericordonna leprosy

With undifferentiated type of leprosy, typical dermatological manifestations are daily. At the same time, asymmetric patches of hypo-or hyperpigmentation are blamed on the skins of ailments with this form of leprosy, which are accompanied by a decrease in skin sensitivity and anhidrosis. Damage to the nerves proceeds to the terminal polyneuritis with paralysis, deformity and trophic kinks.

Shkіrnі show prikordonní leprosy represented by asymmetric pigmented patches, rimmed with nodules or plaques, which protrude, stagnant-red color. Sounds hanging are localized on the lower ends. Neurological manifestations include asymmetric neuritis. Nadal undifferentiated, that near-cordon leprosy can transform into both lepromatous and tuberculoid forms.

Diagnostics

Leprosy is not the same forgotten disease, and its morbidity is related to it in clinical practice, doctors of various specialties: infections, dermatologists, neurologists and others. , papules, infiltrates, humps, nodules), damage to various types of sensitivities on the okremih trees of the skin, sweating of the nerve trunks and other typical manifestations. More accurate diagnosis allows to carry out bacterioscopic detection of mycobacterium leprosy in mucosal membranes of the nose and lesions of the larvae, histological preparations of leprosy humpbacks and lymph nodes.

The results of the reaction to lepromin allow differentiation of the type of leprosy. So, the tuberculoid form of leprosy gives a sharply positive lepromin test; Lepromatous form - negative. In case of undifferentiated leprosy, the reaction to the lepromatous antigen is weakly positive or negative; in case of cordonial leprosy - negative. The functional tests with nicotinic acid, histamine, gyrchichnik, the Minor test may have less specificity.

Leprosy follows differentiation from the disease next to the disease of the skin and the peripheral nervous system. Among the dermatological manifestations of similarity with leprosy, there are hanging in the tertiary period, syphilis, bugatoform exudative erythema, toxicoderma, tuberculosis and sarcoidosis shkiri, lichen planus, leishmaniasis, vuzluvat erythema and other. true amiotrophy of Charcot-Marie-Tuta and in.

Lepri's glee

In this hour of leprosy, there are forty ills. With widened skin manifestations, positive results of microscopy, or relapses of leprosy, ailments are hospitalized to special anti-proliferative settings. In other cases, patients receive therapy on an outpatient basis for the cost of living.

Lіkuvannya lepri to be carried out trivalo that in a complex, course method. One hour, 2-3 protyleproznі are prescribed, the main ones being drugs of the sulfonic series (diaminodiphenylsulfone, sulfametrol and in). In order to eliminate the development of drug resistance, the preparations are used to change the skin 2 courses of treatment. Trivality to the course of specific leprosy glee becomes a sprat of fate. Antibiotics (rifampicin, ofloxacin), immunocorrectors, vitamins, adaptogens, hepatoprotectors, saline preparations are also prescribed. BCG vaccination is indicated as a method of improving immunoreactivity for leprosy.

For the prevention of disability on the cob we are ill for leprosy, massage, exercise therapy, mechanotherapy, physiotherapy treatment, wearing orthopedic aids are prescribed. The important warehouses of complex rehabilitation are psychotherapy, professional reorientation, training, treatment of leprophobia in patients.

Forecast and prevention

The prognosis of leprosy depends on the clinical form of the pathology and the terms of the treatment. Early diagnosis and the beginning of healing (prolonging the fate of the moment the development of symptoms of leprosy) allow us to eliminate the disability. At the time of the late manifestation of leprosy, damaged sensitivity, paresis, which cause deformities, are saved. For the duration of the treatment, the death of patients can occur in the form of leprosy cachexia, asphyxia, amyloidosis, intercurrent illnesses.

The system for the prevention of leprosy transfers the obov'yazkovuyu registration and the appearance of ailments, the hospitalization of previously diagnosed patients, the dispensary for the members of the family and contact persons. Zagalnі profіlaktіchnі go straight to the improvement of the minds and the quality of life, the improvement of immunity. Individuals who have been ill with leprosy are not allowed to work in food and communal areas, child and medical mortgages; cannot change the country of residence.

The world has an impersonal ailment, as if they appeared in old times and dosі oppose people. One of them is leprosy, otherwise, as it is most commonly called, leprosy.

What is it?

It is necessary to grow on the very cob, but it is leprosy. Ailment may be infectious in nature, chronic in nature. Zbudnik є microorganism Mycobacterium leprae. Basically, the problem zachіpaє shkіru human, as well as mucous membranes and the nervous system. The incubation period of the disease is even trival. So, you can get infected with a virus, and the worst manifestations will only start in 5-20 years. Important: this ailment is not strong. Prote yakscho hourly rozpochatiyu therapy, you can get rid of disability.

Roseeveryday

Leprosy is the sickness of the poor. Most disadvantaged sections of the population are infected with it. Near the risk zone are the most extreme regions of the African continent, as well as Brazil, Angola, Nepal, India and others. Ale іz in the middle of the infection today, actively fight the light of sleep. And since 1995, the fate of the skin of a person can be taken well, like that, smut, without costly exultation in case of an illness.

Trochs of history

Leprosy is a sickness, as it was known to the bagmen of ancient civilizations (India, China and Egypt). In the past, the riddle about being ill appeared 600 years before our time. In that hour, vtim, like richly piznishche, such ailments were often ostracized (pardoned, ostracized) not only by suspense, but by close people. With the advent of Christianity, the picture changed little. People who were ill with leprosy, were taken in by the Lord punished for sins, and so they were succumbed to suspense. Only in the middle of the last century, faces were found that could effectively help to prevent illness. And since 1995, the time of preparations in risky areas has been promoted to people on a free basis. Today, the susceptibility to such people is most often tolerant.

Cause viniknennya ailments

How and why blame leprosy (ailment)? Causes doctors dosi nevidomі. And all the things that the incubation period of illness is already trivial. The first symptoms may appear for a few years after infection. The only thing that can be said with confidence is that children are infected with leprosy more often and more, less grown up. You can become infected through close contact with an ill person. If the ailments are relatively rejoiced, then after a singing hour they become safe for the sick. In whom the activity of pathogenic organisms is already high. Less people can become infected with leprosy as a sick person: people with weakened or not yet fully formed immunity.

See the leprosy

Leprosy has two main types:

1. Tuberculoid form. Legsha. It develops in different ways, as the building organism resists attacks of microbacteria.
2. Cordonna form. Something more important than the front shape. However, it often overgrows in the lepromatous form.
3. Lepromatous leprosy. Naivazhcha form. It develops in times of severe weakening or damage to the immune system of the sick.

Symptoms

How does the ailment "leprosy" manifest itself? The symptoms of this are as follows:

1. Injury shkіri, fabrics, yakі contact from poіtryam. The mucous membranes of the nose, mouth, nerve endings are also affected, which are known in the guise of a person. Quite often, leprosy of the flooring penetrates deeply into the skin, which leads to the destruction of nerve fibers. It is worth bringing it to the point that a person becomes indulgent, creates a normal, first look.
2. Leprosy is a disease, which is not the cause of the death of the fingers on the hands. Tse vіdbuvaєtsya zavdyaki re-infection (bacterial infection) and tissue necrosis.
3. The wounds of the villager's shkiri become insensitive to pain, cold, sintering.
4. Onimіnnya kіntsіvok ill. It can also be a waste of sensitivity in kintsivkah.
5. A sick person develops a strong m'yazova weakness.

Form ailments: symptoms

Perebіg ailments for the tuberculotype type are considered as lepromatous leprosy. In the first fall, on the body of an ailing person, they are flat tares, like a white or reddish breeze, and the stench is often covered with small patches. At the time of the attack, the skins of the shells of the nerve fibers become narrower, which leads to a decrease in their sensitivity. As the alarms penetrate the largest storms, they can cause destructive changes in the snow and brushes. Most of the time, the kіntsіvki people suffer. However, let’s say something about those that, with this form of ailment, symptoms can be caused by powerful forces without a trace and irrevocably. As well as the purpose of lepromatous leprosy, then in the guise of people, they most often begin to establish themselves in such a way as the university, or plaques, the skin in these places becomes sensitive, sweats. Large rough folds can be formed on the skins. The guise of a sick person in such a case is the so-called form of the “left muzzle” - a symptom characteristic of lepromatous leprosy.

Diagnostics

Leprosy (ailment) is the problem, which is smoothly manifested. And even more often it will be camouflaged under other illnesses and it can manifest itself through many fates after an infection of a person. Also, we use trivalo and ground diagnostics. With what can you vicorate:

1. Bacteriological analysis of the sound of a sick man.
2. PLR (polymerase lanceuge reaction method) is a costly, yet effective method for laboratory diagnosis of ailments. Yogo meta is a manifestation of the health workers of infectious diseases.
3. Leprominova test (required for the diagnosis of the form of ailment).

Celebration

Later, as if leprosy (illness) was revealed in people, the jubilation was carried out in a different skin stage of the historical step of civilization.

1. With the help of bagatiohs, they rejoiced with haulmug oil to kill leprosy (or leprosy).
2. They gave us sulfonic preparations to change my school.
3. Since 1950, when struggling with this problem, ailment, becoming vicorist, diafenilsulfone (dapsone). However, yoga day can only be swayed through the sprat of rock. Sometimes the jubilation dragged on for 8-10 years. Qi preparations with deaky zamorozhuvacha zamorozhuvannya.
4. On the cob of the 80s of the last century, leprosy began to be treated in a complex way for additional antibiotics: such drugs as "Rifampicin", "Dapson", "Sparfloxacin".

Complicated forecast

Varto tell about those who have leprosy - it’s chronically ill, it’s impossible to find out. You can only galmuvati yogo development. The middle way can be called like this:

1. Striking the skin of the crooks of the ailing to the point of unfamiliarity.
2. That is the fault of the human nervous system.
3. Such an illness can lead to blindness.

In order to avoid such a development, it is necessary for the ailment to be diagnosed in early terms. It is also necessary to constantly fight against the symptoms of illness.

Ailment of the poor?

In the rest of the world, the community began to actively talk about those who have leprosy - not less than the ailment of the most diverse populations. Thus, the deacons of fakhivtsi are stubborn that they are ill enough to oppose the Ukrainian elite. On the very cob it was less about the colossal President Viktor Yushchenko (as it seems, the symptoms are obvious and in the eyes). Dali vcheni began to actively stverdzhuvaty, scho tse and ailment Timoshenko. Leprosy was passed on to each other during the hour of Yushchenko's and Timoshenko's thirteenth contact during Maidan 2004. The symptomatology on Yuliya Volodymyrivna appeared at the hour of the morning. However, there is no reliable information about those who are so true.

Few ailments can have such a gloomy reputation, like leprosy. In the first place, she encourages people in an important way, and even more in a different way, most of the time, it is more aesthetically shocking. In another way, before the wine-housing in 1943 specific chemotherapy, leprosy was practically non-violent. Thirdly, cause mischief for a long time. Tsya ailment was specially invented to cope with the hostility of the unprepared "God's punishment": it opposes people even more vibirkovo and there is still a great incubation period. Until the end of the 19th century, the middle of the medical profession was full of serious discussions about those who were contagious with leprosy and who were not called out, for example, to ribs.

In Greek, the word “leprosy” (λέπρα), which means leprosy, entered the scientific world in the III century BC, since the famous seventy tlumachs in Oleksandriya, Egypt, translated the Old Testament in Greek. Ale, well, this ailment was known to people earlier. In some lands, it allows you to forget about yourself for a long time, in others - to roam. At the beginning of the 20th century, on the outskirts of the Belgian Congo, there was a long area, where 20% of the population fell ill with leprosy, tobt skin five ( Transactions of the Royal Society of Tropical Medicine and Hygiene, 1923, 16, 8, 440-464). And in Western Africa (French Guinea), at the beginning of the day, having found the area, it was devastated to have 32% - the third skin ( Annales de médecine et de pharmacie coloniales, 1920, 18, 109-137). It is important to believe the numbers, but in the literature there is a stench.

Leprosy is a tricky thing. It can be an object of the study of various sciences, from molecular biology to culturology, to read such books, like Umberto Eco's "Im'ya Trojandi" or Michel Foucault's "History of Madness in the Classical Epoch".

However, knowing that we live in the world, that we are evolving, naturally put and such food: did leprosy come from? Or more precisely: where is vinyl out?

Genomics and deduction

"About the adventure of leprosy" - this is the name of the article, published in 2005 by the international group of microbiologists and geneticists in collaboration with Mark Monod, a collaborator of the famous Pasteur Institute in Paris ( Science, 2005, 308, 5724, 1040-1042). Zbudnik leprosy is a non-fertile bacterium, close to tuberculosis sticks (the stink lies up to one genus). The bacterium is called Latin Mycobacterium leprae. Vaughn was introduced by the Norwegian Gerhard Hansen and the German Albert Neisser back in the 70s of the 19th century. And on the cob of the 21st century її far away to do good, to try the virishity of nutrition about leprosy by the methods of equal genomics. Himself for the tse gurt Mono and got to know.

The genome of the leprous beetle was more re-read in 2001. Vіn dosit small, navіt behind the worlds of bacterial genomes, as always small. This genome, without a doubt, has undergone evolution in the future: a significant part of the genes in the newcomer has changed into pseudogenies (this is how the non-functional genes are called, as they have grown, but they have spent the building before being active). In addition, the difference between different populations M. leprae shows that the internal species variability of the genome is even low, wine is vinyatkovo stable in the vastness of that hour. It was not so easy to know in such a genome of a small village, on the basis of which it is possible to inspire at least some evolutionary whiskers.

Roughly speaking, the Mono group focused on elementary warehouse genetic inconsistencies: on single-nucleotide polymorphisms (single-nucleotide polymorphisms, SNPs), as it was possible to know the genome in non-coding plots. Guessing, nucleotides are the only "letters" of the genetic code. DNA includes all types of nucleotides, which are considered to be the same functional group, and may have adenine (A), thymine (T), guanine (G) or cytosine (C). Changes of nucleotides in non-coding plants do not embed the genome into the structure of proteins, which can easily accumulate. In addition, in the case of the genome of the leprosy genome, in such villages, the survivors were able to select only three small loci for analysis (in Latin, this term simply means “miss”).

Well, navit stingy material often allows you to find out about it more importantly, so that you correctly use the deductive method. Let's say we have three single-nucleotide loci. How many types of nucleotides are possible at the skin locus? That's right, chotiri: A, T, G or C. Tse means that the maximum number of possible combinations here is 64 (4 in the third step).

The first valuable information, taken by previous researchers, was similar to that in real populations M. leprae of 64 potentially possi- ble ones present only chotiri: Ts-G-A, Ts-T-A, Ts-T-Ts and T-T-Ts. Tse sharply ask the system that you are playing. Only a little understanding is lost, in the form of a combination everything looks like everything else.

Chotiri rows support hypotheses about the primitivity of skin diseases of various genetic types of leprosy. At the clients the number of replacements is shown, if they were needed, if the leather is a real type (chotiri stovptsya) of the veins of the vyhіdnogo. Pravoruch the number of necessary replacements is summed for all types. The less change, the more plausible is the hypothesis about the primitiveness of this option.

The axis here is the need for a deductive method. Nasampered bachimo, that in three options from chotiriox the first position is C (div. table). In modern evolutionary studies (especially molecular ones), the principle of parsimony has been adopted as such, it is reasonable to choose the same version for other equal ones, because of the least amount of allowance for independent pods. In this way, tse means that C in the first position should be taken into account by the primitive state (it is easy to change, if there is another version of the postulation of additional changes). In this rank, the fourth genetic type, T-T-C, is still excluded from the candidates for the role of the most recent one.

At the other position, three of the options from chotiriox cost T. In a similar order, let it go, which is the most primitive. Among the candidates for the most recent role, the first genetic type (C-G-A) is also included.

Also, in the most recent genetic type of leprosy, the first position C was in the first position, just like the other T. Ale C-T-A chi C-T-C? The primitivness of that second variant is equally modern. Razdіlna zdatnіst sutо genetic approach here vycherpuєtsya.

Prote be-yak evolution in the abstract space of genotypes, and in the vast geographic one. Important additional information can be taken away by placing genetic types on the map of the world. Fortunately, Mono's group has developed bacteria from different regions of the Earth.

For clarity, genetic types M. leprae were identified by a color code. The first type (Ts-G-A) is “yellow”, the other (Ts-T-A) is “red”, the third (Ts-T-Ts) is “violet” and quarters (T-T-Ts) are “ greenery." Judging by the genetic mirroring, the role of the most recent can be claimed by the "red" and "violet" tipi. And now we wonder what seems to us to be geographically wider.

Genomics is focused on geography

On the back of the head, we’ll put a dry zvedennya otrimanih danikh.

"Zhovty" type: Hidden Africa (pvdenny part), Madagascar, India, Korea, Malaysia, Philippines.

"Chervoniy" type: Skhіdna Africa (Ethiopia, Malawi), Nepal, pivnіchny skhіd Іndії.

"Violet" type: Pivnіchna Africa (Morocco), Western Europe, most of the American continents.

"Green" type: Zahidna Africa (for a day in the Sahara), the islands of the Caribbean Sea, Brazil.

In New Caledonia, there are three types (“yellow”, “red” and “violet”), but there are clearly traces of the settlement of the island by various ethnic groups in the colonial period, and we can not argue at the price.

Which type is the most recent? If you choose between "red" and "violet" types, then the shortest, obviously, "red" types. European leprosy is infinitely less old (for example, in Italy it is still behind the hours of the Emperor Augustus, so at the borders of our land, it was known to be unknown). And in Africa, the "violet" type is less common in the Sahara, for example, in Morocco, - there, de vyazok іz evropoy it is clearly embossed. Prote the area of ​​the "red" type hoards the whole of Northern Africa. Does this mean that this is fatherland leprosy? As much as possible.

True, even the hypothesis of the Asian adventure of leprosy, yak Mono and the authors of the same did not immediately become apparent. But from the genetic point of view, the version is less modified: it transfers at least one additional nucleotide change. Better for everything, let’s see not the “zhovty” (Asiatic) type, but the “chervony” type. Tse means that the leprosy of Vinicla is there, de y vigliad Homo sapiens: near the depths of Northern Africa.

Out of Africa, leprosy took a break before going to the Close Skhid, and then two small roads - to Europe and Asia. Migration in the Bik of Europe gave rise to the "violet" type, migration in the Bik of Asia - "zhovty". The ancient powers of the Indian subcontinent and China appeared to us as a living center for the rest. Europe simply did not have such a large number of people for a long time;

Tsikavo, which is the island of the "red" - similar to the African type of designation itself on the Indian subcontinent (Nepal, pivnichny skhid of India). Possibly it is a relic that has been lost in the bud migration.

From the other side, "zhovta" - Asian - the line of leprosy was revealed in Africa. But what about Africa? Tse Madagascar is a part of Northern Africa, roztashovan approximately opposite. The native inhabitants of Madagascar are the Malagasy, as if they were Indonesians. And in the middle part of Northern Africa there are old ports, oriented towards trade with Asia - Malindi, Mombasa, Zanzibar. There is no doubt that leprosy was brought here from Asia itself through the Indian Ocean.

Dzhe tsikavoy є the share of the "green" line of leprosy. It is even more genetically distant from the imovirno vihid "red" type, and wider it is bordered by West Africa for a day from the Sahara. How did she go there? Possibly, along the path of long-standing continental migrations through Africa from the very beginning. This continent is not particularly easy for distant mandrikovs, so the isolation understood. Or maybe, the Finniki, like they went on the ships of the African coast of the Atlantic, they brought leprosy there from the Mediterranean in their own time (here you can read Ivan Efremov’s novel “On the Edge of the Oikumeni”, de description itself is so expensive). It is similar to the mischief of this version to say that the “green” type of leprosy is genetically closer not to “red”, but to “purple” - for the Mediterranean, like for Europe, which is characteristic of the rest itself.

On the American continents, leprosy is mostly "purple", which looks completely natural: even America was colonized by Europeans. In the Antilles and Brazil, the “green” type of leprosy is growing, but it is also clearly explained by the Atlantic slave trade - the slaves were transported most importantly from Western Africa in their own time.

It is noteworthy that the Europeans seem to have contrived to infect with leprosy the widest nine-banded armadillos in Pivdenniy, Central and Pivnichniy America. Dasypus novemcinctus. The nine-armed armadillo is perhaps the only biological species, Crimean people, slender to the point of ailment. On the pivdni of the United States and in Mexico, they managed to create natural environments. So axis, armadillos have a genetic type M. leprae- “violet”, exactly, as a trace of eye-catcher, based on the fact that Europeans brought leprosy to America.

Ask here all the same zalishaєtsya chimalo. But still, we have before us a bright evolutionary scenario.

...І with archeology

The scheme of the evolution of the leper's bugger, proponed by the Mono group, for the beauty of the solution by Sherlock Holmes, the task of dancing people. Of course, I figured out that the documents didn’t go wrong. A few years later, the same group published a clarifying work, in a sort of genetic type M. leprae divided already into 16 subtypes ( Nature Genetics, 2009, 41, 12, 1282-1289). There is nothing there that fundamentally changes the picture, but there are details. For example, DNA M. leprae, revealed in a leprosy skeleton from Egypt for about 1500 years, was shown not to be of the “red” type (as one might think), but of the “violet” type. Those same in Turkey. You can see that the range of the "violet" type is overwhelming the entire Mediterranean. In the exchange of leprosy by the sprouts of the Near Descent, that Europe - at the hour of cross-country marches, for example - took the fate of the "violet" line of the microbe.

If there is a “zhovtoї” line, then, maybe, on the cob it penetrated from Africa to Asia, not through a land place between them (it would be easy to think again), but rather along a different path. Yakshcho "violet" type M. leprae having collapsed from Egypt through Sinai, Palestine and Syria, then “zhovtiy” - directly from the Somali breeding island of the pivine coast of the Indian Ocean. Behind the Great Arc, as if the heroes of Efremov would hang.

Here, however, let me think.

Mayzhe, at the same time with the release of the new article of the Mono group, data appeared about the knowledge of leprosy skeletons in India as far back as 2000 years before our time. PloS One, 2009, 4, 5, e5669 (special photo). There are no molecular confirmations there, but the anatomical (more precisely, osteological) ones look hostile. It is quite natural that the authors of this opinion put the hypothesis of the Mono group under doubt, assuming that the typical type of leprosy is not “red” (African), but “zhovty” (Asiatic). As far as we remember, such a version and the Mono edge itself is not seen again. Ale naytsіkavіshe: the place of knowledge of these skeletons is not easy India, but Western India. This is the area of ​​the most ancient civilization of the Indus Valley, the same area, where the famous places of Mohenjo-Daro and Harappa were. The Sumerians and Akkadi called this country Meluhkha (History of the Ancient Descent. Edited by B.S. Lyapustin M., 2009).

Here the authors of the Indian version speak about the foundation of 2–3 thousand years before ours, the so-called single sphere of mutual modality, to which Mesopotamia, Turan, Meluhha and the kingdom of Magan on the Arabian Piostrov were included. De not for the leprosy of Vinyl, those who were expanding in this sphere, - for sure. The Russian civilizations were a life-giving medium for her.

Where did you come from? It's a pity, but there are no genetic data, but it's possible to guess the hypothesis of leprosy coming from India.

"For ever and ever"

In one recent work, the estimate is: close to 10 million years ago ( PLoS Neglected Tropical Diseases, 2014, 8, 2, e2544). Tse duzhe rich! The most recent and most upright relative of the human being - Sahelanthropus - is alive only 6-7 million years ago. And 10 million years ago, our upright hіba started to take shape. And at any time, all the early stages of the evolution of people were expected by Africa. Like an ancient leprous alarm clock, then it will appear in a moment only there.

Apparently, there were a lot of infectious ailments so chi were taken by people like creatures, with whom I had a chance to contact ( Nature, 2007, 447, 7142, 279-283). About tuberculosis, which is also referred to by a microorganism of the genus Mycobacterium It's a hypothesis that people took yoga from savages. But, however, it’s a crazy thought that it’s already a long time ago that a human infection that infected the zhuynyh suddenly ( PLoS Pathogens, 2005, 1, 1, e5). There are no such super-boys for mischief, because there are no serious charges for them. Tse ill people. It is true that armadillos are ill with leprosy and rarely (literally in lonely vipadkahs) on chimpanzees, as well as deaks and other African mawpis. Ale, it seems that all the stench took off the leprosy again and again in people. The leper chimpanzee, brought from Western Africa, has a genetic type M. leprae appearing "green", tobto the very same, that the expansion of the middle of the local meshkantsiv ( Future Microbiology, 2011, 6, 10, 1151–1157).

Also, leprosy is a specific disease of people. Vrakhovuchi її ancient times, to say more briefly not "people", but "hominids" (in the narrow sense of the word, upright primates). What are the peculiarities of їх - our way of life was zoomed in by її іsnuvannya?

The great anthropologist Owen Lovejoy blames the uprightness for a new breeding strategy that allowed the hominids to drastically increase the number of their populations. With this strategy, females spend a large part of their life in a small safe "nesting zone", taking care of the children (straight is necessary for them, call for a robotic hand). Males, not shy of children and females, can greatly expand their territory, moving far and wide foraging trips. The new structure of society has created new possibilities, and new risks. In the mawpyachy stage, the viability of individuals, those who have suffered from a serious common infection, which is better for everything, is not high. And the axis of the hominid cosmos, clearly divided into the “nesting zone” (where the females live), the zone of foraging and watering (where the males go) and the absolutely wild world, - here the lepers could know for themselves even if it’s gloomy and unsettled, but all the same still niche.

“At Brueghel, for the convergence to Golgotha, where all the people follow Christ, lepers watch in the distance: such is the place for ages and ages,” wrote Michel Foucault. Still not knowing that it is “for ever and ever”, it is possible, to endure millions of fates. Leprosy is a long-standing shadow of human society. It's scary to show, it's a long time ago. One of the quiet products of evolution, which you most want to explore. Good luck, for the good fortune of nareshti, allow you to grow.

In this article, we can see what is the cause of leprosy, how it is infected, which is why people get sick in special leper colonies. Let's figure out how to protect yourself from a terrible ailment, which you should work with if you suspect leprosy. You know how effective methods of investigation are to find out what to check for the hour of infection.

Appointment

Leprosy - We see hundreds of contagious infections. Since there may be a trivaly incubation period - then after infection it may not practically appear until 5 years, it is necessary to know the specifics of the infection, so that you can immediately show the first symptoms.

Leprosy has a lot of names - Finnish ailment, mournful ailment, Hansen's ailment, St. Lazarus' ailment. Previously, leprosy was called leprosy.

Speaking scientifically, leprosy is chronic granulomatosis, which is a chronic infection of the body. An alarmist is the mycobacterium Mycobacterium leprae, born in 1871 by the Norwegian Hansen. Recently, in 2008, a new variety of the bacterium Mycobacterium lepromatosis was discovered. This bacterium does not make superchicks and does not make capsules. Surprisingly, but the reproduction of the bacterium in a special living medium did not work.

Today in Russia there are even few ills for leprosy, so the epidemic is small, and until that day, singly flus of infection trap.

The most widespread leprosy is in the Lower Volga region, in the Pivnichny Caucasus, and near the Baltic states.

Ways of infection that group of risiku

You can get infected with leprosy in the form of sick people, both in the case of a povitryano-crippled, and in a contact-butt route. Mycobacterium leprosy in large numbers is found in nasal mucus, sleigh, slit, breast milk and blood. Why does one person get sick with five-way contact with sickness, and another person can lose a healthy one with a tribal splintering, medicine is still unknown.

It is important that some people develop resistance to illness - that stench is unacceptable to her. It is easier for children to become infected, especially if they develop into allergies.

Intrauterine leprosy is not transmitted. If a woman is ill with leprosy, then the child will be born healthy, only if she should be isolated from her mother in order to get rid of the infection.

People with poor immunity, high-grade diseases (alcoholism, smoking, improper eating) are most at risk of becoming infected. Also, social and economic officials are pouring in. Most often, leprosy occurs in Asia, the lands with low living standards.

Symptoms of teepee lepri

After infection with leprosy, there is an incubation period, an hour, if the disease does not show itself in any way. Standardly, such a period lasts 4-5 years, so you can get infected and don’t know anything about it.

Rarely, the incubation period is short - symptoms appear after 3-5 months. Also, there are cases of asymptomatic nosebleeds for 10-50 years.

The patient's lower back is beginning to feel unwell - there were swells, severe weakness, problems with the mucosal-intestinal tract, nasal bleeding is common.

Crimean shkiri, leprosy attacks the nervous system, and neurological pain manifests itself.

Then the ailment develops as the main symptomatology. And there are three paths, that's three different lepri.

Lepromatous type

This variety is characteristic of the most skinny manifestations. On the shkir, people are covered with red patches, sometimes with a purple color. An important sign of a change in sensitivity - in the area of ​​\u200b\u200bthe flames can be named, pokolyuvannya, or else the loss of sensitivity of nerve endings.

Step by step the daedals are melting with lashes, the shkir at these places are sweating, the underclothes of the klitkovina are falling behind, de z'yavlyayutsya vuzli. Flames can spread all over the body, and more often they appear on the shkiri on the ridges.

There is a shock of disguise, with whips they start from the vuh, go into disguise, supporting mimicry. Such a manifestation is called the "Left's face".

Likewise, the underarms of the red to the rusty color are blamed, as they turn into the visor for an hour. From such virazok, billions of bacillus lepri are seen.

The mucous membrane of the nose is also affected. At the nose, crevices and folds are established, lesions can erode the cartilaginous tissue, then one more characteristic symptom appears - the tip of the nose is lifted.

The ailment can expand on the mucous membrane of the mouth and larynx, which causes hoarseness, and when the ligaments are affected, the person speaks.

The eyes of the people are in awe, the eyes are also settling there, without exuberance you can spend money. The lymph nodes of the infected person are greatly enlarged, but if they are painless, they are collapsed.

Lepromatous type of disease rots the nervous system. Symptoms range from the simplest nerve disorders to severe psychosis.

The peripheral nervous system is also affected, which manifests itself as neuritis and polyneuritis. Rukhovi discord often traplyayutsya.

Sensitive reactions are seen - cold is mistaken for warmth and at the same time. Dalі nastaє povna vtrata sensitivities shkіri. Through the destruction of the blood circulation, a mutation of the hands and feet occurs.

The cystic skeleton is bulging, the nails are deformed. Stop or the hands become flat, like seals. So you can sweat sweat and sweat, then the skin becomes completely dry.

At once, the organs of the people are attacked, the legens, the liver, are growing stronger. Hormonal decay is vibrating, people are getting old fast, there is a pre-menopause in women and impotence in people.

Tuberculoid type

The Danish variety of leprosy may be more calm. Here, the strikes of the shkir are also seen.

Ale tse is clearly adorned with bezbarvnі plyami or yaskravі chervonі show with papules along the edges, similar to lichen. Then the papules get angry to buy, fixing large plaques, the skin in the center of which will atrophy with time.

Torkaetsya and peripheral nervous system. Here sooner the sensibility of the shkiri disappears. The ailment does not see heat and cold, does not see the painful sight of the skin, then we know and tactile notice - dotik.

The tuberculoid type is characterized by hair loss, sweating on the wounds of the shkiri.

non-differential type

Such a variety is seen in the daily screenings. Possibly a sprat of an ignorant and spreading flames on the shkir. This moment to introduce into Oman that complicates diagnostics.

It is possible to have papules, but they do not have leprosy, which can be treated like dermatitis. Most of the self-feeling of the ill is also destroyed. The nervous system is affected. The deformation of kіntsіvok is possible - "kіnsk foot", "kіgtepodіbna brush".

This type of leprosy is gradually transformed either into lepromatous or tuberculoid. If the test for lepromin reaction is positive, then the transformation may be only more mild tuberculoid form. As a result, the result is negative, as a whole there is a possible lepromatous form.

Diagnostics

Leprosy is difficult to diagnose. On the other hand, patients with shinny hangings most often go to the dermatologist and do not cause minor ailments with shinny problems. Leprosy can be mistaken for genodermatosis, sarcoidosis, tuberculosis, vasculitis, dyschromia and other infections of the skin.

Here it is important to report the patient's history, show the skin with neurological symptoms, treat the patient's skin for the presence of nerve endings near the skin lesions.

For diagnosis, bacteriological and pathomorphological studies are carried out on the material that is creamed from the nose, viscera (which is also the case), larynx. The method is called "zabarvlennya for Ziehl-Nielsen".

Bacteria leprosy acid-resistant, such micro-organisms are filthy zabarvlyuyuyutsya roses barvnikiv, so the sample is zabarvlyuyut special carbolic fuchsin Tsilya, then treated with acid. Because of this, only the leprosy bacteria do not vanish, but become overwhelmed with bright-chervonim.

In the case of an undifferentiated type of disease, the diagnosis cannot be made because the leprosy bacteria are present in the worms from the nose or from the nose.

For diagnosis, a nicotine test can be performed. For this, nicotinic acid is administered intravenously, after which the skins become red with leprosy patches and swell.

Celebration

No matter how many names I call that terrible symptomatology, leprosy rejoices. For whom special antimicrobial preparations are suitable.

Appointed faces are assigned to the ailing person for leprosy with a trivalid course.

Start the leprosy bacteria to die after 12 years of leprosy, the course must be continued, shards of leprosy can recur for a few years. It is standard trivality to become 2 fates.

If the course of ailments is taken into account "dignity", so that wines do not become a threat to those who are sick, but still people are guilty of regularly undergoing a medical examination, the stink is changed to the appearance of a child.

Liprozoria

Tse special medical mortgages, where the sick are placed on leprosy for healing. There are 4 leper colonies in Russia: in the Stavropol Territory, Astrakhan, Krasnodar Territory and the Sergiev Posad District of the Moscow Region.

Patients who have been licked, as if they are being looked after in such places, do not allow the possibility of contact with the outer world, stench can contact with healthy people, vizhzhdzhati to the place.

Ale, the shards of the great risk of relapse, are left at the specialized installations.

The leaders of modern therapy, the patients with lung disease, miraculously look like healthy people. Rarely suffer from leprosy with characteristic defects of the kinks, often do not reach the “left hand” ones.

In Europe there are leprosaria every day, there the proclaimed patients are allowed to go home.

In Russia, it is important that the leprosy is unviable to the end, to bring all the offspring of a person to a terrible sickness. However, the Russian leper colonies have a high level of trivality of life, as the doctors themselves stagger, people die of old age, and not of leprosy.

In this video, you can get to know the patients of leprosy, which was spread in the Sergiev-Posad district of the Moscow region and recognize the thought of a leprologist doctor about this ailment:

Folk methods

Zasobi folk medicine under the hour of leprosy, sorry, Marni. However, the mіstsevі procedures shkіri can be combined with the main procedures.

Aloe juice compress

How to stop: vychavit with aloe, apply compresses on the lesion of a woman's house for a day for a month, repeat the course of skin treatment for 2 months.

Result: scarlet scarlet is repulsed by strong anti-powerful powers, with such exuberant shkirn, it will show lepri to go richly shvidshe. Alece for systemic medical therapy with special preparations.

Prevention

• As in this case, if you fall ill with leprosy, it is necessary for everyone to undergo medical examination for a short time.
• Newly born children need to be isolated from their mother and translated into piecewise vigodovuvannya.
• Children of a high school age can go to primary schools, however, the infection should be treated 2 times a day.
• Let us, who are in close contact with ailments, conduct a lepromin test and the Mitsudi reaction. Suspensions of mycobacteria are injected into the skin and the reaction of the organism is observed. If the immune system is strong, then the risk of infection is minimal. For the presence of the immune system, the person is subject to detailed obstezhennia.

Food service

I was diagnosed with leprosy, sent to the leper colony for treatment. Am I going to die there now?

Leprosy has ceased to be a deadly disease. Dane, ill, especially revealed at an early stage, is kindly welcomed. The course of therapy is threefold, if a person is not contagious and can lead the best way of life. Proteo-infected leprosy has been fenced off to be used in the food industry and in children's mortgages. You will stand on the guise of that regularly pass obstezhennya.

My sister was diagnosed with leprosy, everything is passable. Ale sister vagіtna! Lіkar seems to be a threat to the child, don't you, is it so? The sister is staying at the leper colony, it seems, after the half-hearted child is handed over to her homeland, and the sister is left to be treated.

Doctors make a ration. Leprosy is not transmitted intrauterine. The child can be born healthy. However, in the wake of the fall of yoga, it is necessary to isolate the mother from the mother's point of view, so that one can easily become infected through mother's milk.

Our distant relative was diagnosed with leprosy. We don't talk so often, but now we need to go through obstezhennya. I have two children of schoolchildren, now they are not allowed to go to school without permission, why stink on the right?

Mustache relatives and people who are staying with a close contact are obliged to undergo medical treatment. In order to see the children of the school, now they will have to undergo medical examination of the girls on the river. For grown-ups, do a diagnostic test carefully.

What to remember:

1. The leprosy is a mycobacterium Mycobacterium leprae or Hansen's wand.
2. You can get infected with leprosy in the form of sick people with a contact-button or a covered-crippled path. However, intrauterine infection is not transmitted - women infected with leprosy give birth to healthy children. Ale of all offspring is deprived of schilnist before infection.
3. The incubation period after infection, if the disease is not practically manifested for oneself, is usually 4-5 years. Vignyatkas have sprats of months. A precedent for an incubation period of 10 - 50 years has been set.
4. The most important type of leprosy is lepromatous. Tuberculosis type proceeds more easily. They also designate a non-differentiated type, which in turn transforms into one of the above listed main ones.
5. Leprosy is subject to scrutiny, the course of special groups of antibacterial drugs is threefold. Dali ailments are not contagious, ailments do not progress. However, obov'yazkovoyu є shorіchna prophylactic medical examination and dovіchny lіkarnyany form.

Leprosy, or Hansen's disease, or leprosy is a chronic infectious disease that is caused by the acid-resistant bacillus Mycobacterium leprae and is characterized by lesions of the nervous system, mucous membranes, skin, internal organs and musculoskeletal apparatus.

Symptoms of leprosy can vary from painless skin lesions to peripheral neuropathy.

Diagnosis of leprosy disease is based on a typical clinical picture of skin lesions and peripheral neuropathy; confirmed by biopsy.

The exaltation of leprosy is rooted in the drug dapsone taken at the same time with other antibiotics.

Cause lepri

For a long time it was considered that the only natural reservoir of the ailment of leprosy is the human being, but not long ago it was established that the carriers of infection can be and human-like primates and armadillos.

A leprosy alarm clock can be used when coughing, coughing and seeing the secret of an infected person. Also described are the types of infection through microtrauma on the mucous membranes and skins. Individuals with chronic illnesses, reduced immunity, and living in unsanitary minds are at a higher risk of infection.

Mycobacteria are consumed along the bloodstream from different organs and settle there. Mycobacterium leprae can be matured enough, so the incubation period of infection is defined by the term for up to ten years.

Form the symptoms of leprosy

Leprosy ailment, as a rule, begins with the appearance of ill health, weakness, malaise, drowsiness. Illness on leprosy can be stinged on the names of fingers, hands, I will appear on the ridges of the chin humps.

For the type of symptomatic symptoms of leprosy, the following forms of illness are seen:

• Tuberculoid leprosy. The best option for the development of ailments. At times, there is damage to the skeletal curves and the nervous system, the functions of the internal organs are disrupted. At the cob stages of illness on the surface of the skins of ailments, leprosy can appear one or more patches, papules or plaques, which can be red or light, lower or lower. Then the elements start to get angry one by one, satisfying the chimerical middles with burgundy contours, raised roll-like edges and thinned skin in the center. On kіntsіvkah, that person can blame puffy-like tutelage. The symptoms of leprosy, associated with lesions of the nervous system, are manifested by the fact that instructing these nerves to be felt painfully sweating nerve storms (often there is a lesion of the ulnar, exchange, pruritic, facial nerve). The motor activity of the fingers of the hand is broken, and such obvious signs of leprosy are formed, like “a foot hanging down” and “a bird's paw”. Through those who eat the shkiri break down, it becomes a lamb, it can develop a mimic wind of the body of the body, which wedmerla (mutilation);
• Lepromatous leprosy. Naivazhcha form of illness. It starts from appearing on the surface of the skies of gleaming patches (red or light). With this, sensitivity in the zone of damage is saved. Through sprats of rocks in the area of ​​\u200b\u200btheir flames, hair begins to fall, knots and plumes develop. As if puffy-like pits are localized in the area of ​​the brow, superciliary ridges, external conchas, then they look like a “left person”. To finish it often on the poohlins, virazki are vibrated, as if they are infected, and after being driven in, rough scars are formed in the same place. Also, in patients with leprosy, this form shows lesions of the mucous nose with perforation of the septum and a change in the shape of the nose. The pathological process can spread to the empty mouth, throat, which leads to a change in voice. At the end of the period, the sensitivity of the lower and upper endings is broken, contractures of the fingers are formed, the arms are fixed, so as not to fight. In ailments, lymphatic nodes are lit for leprosy. In 80% of depressions, the damage to the eyes is caused, which leads to blindness. Granulomas that develop in the cysts lead to ruptures and fractures. Granulomas can be established in legenia, nirkah, selezintsі, pechenci, leading to destruction of robotic organs;
• Near the cordon leprosy form. Characterized by the presence of the characteristics of the two main forms of illness and mildness.

Diagnosis of leprosy

Diagnosis of illness is based on the characteristic clinical manifestations of leprosy and confirms microscopic findings of biopsy findings.

In order to take biological material on the skin, a shallow cut should be made and scratches taken from the area of ​​granulomas.

Also, for follow-up, you can take samples of mucus from the empty mouth and nasopharynx, as well as from the lymph nodes.

Lepri's glee

In this hour, for the mind of the hourly visits from the rejoicing, the leprosy may be more vilіkuvan.

The exaltation of this ailment is a trivial process, a method of such an ailment of the sick, the prevention of re-development of this therapy is more complicated. Ailments for leprosy lead to hospitalizations to special deposits - leper colony.

The main cause, which is victorious in the treatment of leprosy, is dapsone, which is prescribed in a daily dosage of 50-100 mg. You can also use vikoristan such as rifampin, clofazimin, etionamide.

Recently, it has been established that such antibiotics as minocycline, clarithromycin and ofloxacin can suppress M. leprae and change the infection of the skin. Їx combined activity of visch, lower clofazimine, dapsone and etionamide.

A cream of antibacterial treatment for leprosy, and antiseptic therapy is also being established.

Even after 6-12 months after the course of treatment, the patient does not show mycobacteria, it should be transferred to the outpatient regimen of treatment.

With the method of social adaptation, if you have suffered a disease, you are recommended psychotherapeutic treatment. Because of the method of boosting immunity and the prevention of infectious diseases, such people will require a full meal, likuvalnaya physical culture, physiotherapeutic lukewarm. Since the leprosy has been transferred, the sensitivity of the noses is broken, then the stench is to be guarded against the blows, so as not to allow injuries on the butt.

In this order, leprosy is not a serious infectious disease. Irrespective of those who are more likely to turn away for their timely slaughter for medical help, they are forced to live with people until the end of life. Therefore, in order to prevent leprosy, it is necessary to carry out preventive visits, direct to improve the minds of the mind, improve the immunity and the quality of life.