How to prepare atropine for the introduction of a child Atropine is indicated before ingestion. Interaction with other medical care

Pharmaceutical form: rozchin for injections Stock:

storage for 1 ml.

Dyucha speech: atropine sulfate (for an anhydrous rechovina) - 1.0 mg;

Additional speeches: hydrochloric acid 1M - up to pH 3.0-4.5, water for injections - up to 1.0 ml.

Description:

Bezbarvna or trohi zabarvlena prozor native land.

Pharmacotherapeutic group:M-anticholinergic ATX:

A.03.B.A Beladoni alkaloids, tertiary amines

A.03.B.A.01 Atropine

Pharmacodynamics:

M-cholinergic receptor blocker is a natural tertiary amine. It is important that the M1-, M2- and M3- subtypes of muscarinic receptors are associated with each other. It flows both on the central and on the peripheral m-cholinergic receptors. Changes the secretion of sloughing, sloughing, bronchial, sweat cavities. Decrease the tone of smooth pulpsinternal organs (including bronchi, organs of the herbal system, urethra, sich michur), altering the motility of the intestinal tract (GIT). Practically does not affect the secretion of zhovchі and pіdshlunkovoї zoloza. At medium therapeutic doses, there may be a calming stimulating effect on the central nervous system (CNS) and an alimentary sedative effect. Central anticholinergic disease explains the development of atropine and tremor in Parkinson's disease. At toxic doses, it causes agitation, agitation, hallucination, coma. changes the tone of the bulging nerve, which leads to an increase in the frequency of the heart rate (with a slight change in the arterial pressure (AT)), an increase in the conductivity in the bundle of His.

At therapeutic doses, it does not significantly affect the peripheral vessels, but vasodilation is suspected in case of overdose. Pharmacokinetics:

After systemic administration, it is widely distributed in the body. Penetrates the blood-brain barrier. Significant concentration in the central nervous system reaches 0.5-1 year. Communication with plasma proteins is less. Drinking period(Ti/2) become 2 years old. Get out of the cut; close to 60% - at the same time, a part that was lost - at the sight of products of hydrolysis and conjugation.

Shown:

- Spasm of the smooth and lingual organs of the PCT; Virazkovy ailment of the stool (in the phase of aggravation) and the twelve colonies (in the phase of aggravation), hostrial pancreatitis, hypersalivation (parkinsonism, poisoning with salts of important metals, with dental implants), nirkova kolka, liver kolka, bronchospasm;

- premedication before surgical operations;

- atrioventricular block; bradycardia; abuse by m-cholinomimetics and anticholinesterase speeches (reverse and irreversible diseases).

Contraindication:

Hypersensitivity, closed-cut glaucoma (mydriatic effect, which can lead to an increase in internal pressure, can cause a hostile attack), tachyarrhythmias, severe chronic heart failure, ischemic heart disease, mitral stenosis, ref lux-esophagitis, hernia of the stravochid opening of the nirkov insufficiency, intestinal atony, obstructive disease intestines, paralytic ileus, toxic megacolon, nonspecific virazkovy colitis, xerostomia, myasthenia gravis, obstruction of the cut or sciatica to it, sickness, which are accompanied by obstruction of the cuticles (including toxicosis of the vaginal stі, Down's disease, infantile cerebral palsy, lactation period

If you have had one of the illnesses (stands), before taking the drug obov'yazkovo consult a doctor.

With care:

Hyperthermia, acute glaucoma, chronic heart failure, arterial hypertension, chronic disease of the leg, acute hemorrhage, hyperthyroidism, 40 years of age, vaginess.

Vagity and lactation:

Atropine penetrates through the placental barrier. Adequate and strictly controlled clinical studies on the safety of atropine ingestion during pregnancy were not conducted.

With intravenous administration in case of vagity, or not too early to the fold, the development of tachycardia in the fetus is possible.

The drug should be contraindicated in case of vaginess less in depressions, if the potential measles is true potential risk for the fetus.

Atropine appears in breast milk at trace concentrations.

If necessary, the drug can be injected into the breast during lactation.

Method of stosuvannya that dose:

For the treatment of acute pain in cases of mucosal and duodenal ulcers and pancreatitis, in case of nirk, hepatic colitis, the drug should be administered subcutaneously or internally at a dose of 0.25-1 mg (0.25-1 ml in each case).

For usunennya bradycardia - intravenously at 0.5-1 mg, for consumption, after 5 minutes, the introduction can be repeated.

With the method of premedication - internally 0.4-0.6 mg 45-60 minutes before anesthesia.

For children, the drug is administered at a dose of 0.01 mg/kg.

In case of disorders with m-cholinergic stimulants and anticholinesterase methods, administer 1.4 ml intravenously, most importantly in combination with cholinesterase reactivators.

Side effects:

From the side of the herbal system: dry mouth, constipation, intestinal atony.

From the side of the central nervous system:bіl head, confused.

From the side of the cardiovascular system: sinus tachycardia,exacerbation of myocardial ischemia through supramundane tachycardia, tympanic tachycardia and tympanic fibrillation.

From the side of the sieve system: difficulty in cutting, atony of cut michur.

From the side of the organs a little: photophobia, mydriasis, accommodative paralysis, impaired tactile sensation, movement of the internal pressure.

As if there were any side effects, or you remembered whether there were any other side effects that were not listed in the instructions, tell me about the healer.

Overdose:

Symptoms:Dryness of the mucus membrane of the empty mouth and nasopharynx, damage to the bowing and movement, dryness of the skin curves, hyperthermia, mydriasis (increased variability of side effects); Rukhove and movement of awakening, memory damage, hallucinations, psychosis.

Likuvannya:Anticholinesterase and sedative drugs.

Interaction:

In case of one-hour stagnation with anticholinergic effects and the effects that may have anticholinergic activity, anticholinergic effects are increased.

With one-hour exposure to atropine, there may be an increase in the absorption of zopiclone, mexiletin, a decrease in the absorption of nitrofurantoin, and yogo administration with nirks. Improving the therapeutic and side effects of nitrofurantoin.

With one-hour stagnation with phenylephrine, it is possible to move the arterial pressure. Under the injection of guanethidine, it is possible to change the hyposecretory di atropine. Nitrati zbіlshhuyt ymovіrnіst pіdvishchennya vnutrishnoochnogo vice.

Procainamide potentiates the anticholinergic action of atropine.

Atropine reduces the concentration of levodopa in blood plasma.

Injected into the building keruvati transp. since. that tricky.:

In the period of rejoicing, it is necessary to take into account the transportation barriers and take other potentially unsafe types of activity, which will increase the concentration of respect and the flexibility of psychomotor reactions.

At the warehouse of the drug, the main speech atropine sulfate that dodatkovі skladovі zalezhno vіd yogo form.

Release form

The main form of release of Atropin is: injectable variety and drops of eyes. Rozchin packages in 1 ml ampoules, and eye drops in dropper bottles of 5 ml.

Pharmacological activity

May drug cholinolytic dієyu, zdatnoyu blockade of M-cholinergic receptors.

Pharmacodynamics and pharmacokinetics

Atropine is an alkaloid, which is also found in certain roslins, for example, beladoni, dope, bilen and others. In medicine, speech is victorious, as it is called. It should be noted that the form of the release of this component is a granular or crystalline powder of a white color that does not smell. Vin is easily separated from water or ethanol, showing stability to chloroform and ether.

Pharmacological group, up to which the whole drug should be included, є cholinolytic. In this case, the mechanism of action includes blocking of m-cholinergic receptors.

The stagnation of this speech can lead to amidriasis, paralysis of accommodation, movement of the internal pressure and xerostomia. It is also noted to suppress the secretion of bronchial, sweat and other diseases. Relaxation in the smooth muscles of the bronchi, zhovcho-or sechovidnyh organs, shkt, so speech acts as an antagonist and has an antispasmodic effect.

In great doses, the nervous system can be damaged. If Atropin is administered intravenously, showing the maximum effect, it is seen after 2-4 whilins, and as a rule, there are eye drops, then after 30 whilins.

The use of antacids, albeit against Al3+ or Ca2+, may reduce the absorption of the basal tract from HCT. Active tricyclic antidepressants, , phenothiazini , Khinidin, antihistamines and other drugs with m-anticholinergic features can contribute to the development of systemic non-significant effects.

Nitrat zdatnі viklikatі vіdvishchennya vnutrіshnоchnogo vysku, and Atropin - zmіniti absorption parameters і Mexiletin .

especially vkazіvki

The use of Atropine in distal AV block, which is accompanied by wide QRS complexes, is ineffective and, in general, is not recommended.

If the drops are dripping at the conjunctival sac, then carefully press the lower tear point so that the drips do not get into the nasopharynx. Conducting subconjunctival or parabulbar insertion is recommended for one-hour indications to reduce tachycardia.

Wash away the sale

For a prescription.

Wash away the savings

To take care of any form of the drug, you need a dark, cold place, inaccessible to children.

The term of appurtenance

For injectable spray - 5 doses, for ophthalmic drops - 3 doses.

Atropin analogs

Signs for the ATX code of the 4th level:

Main analogues: , і .

Gross formula

C 17 H 23 N 03

Pharmacological group of speech Atropine

Nosological classification (MKH-10)

CAS code

51-55-8

Characteristics of speech Atropine

Atropine sulfate is a white crystalline abo-granular powder, odorless. Easily soluble in water and ethanol, practically insoluble in chloroform and ether.

Pharmacology

Pharmacological activity- cholinolytic.

Blocking m-cholinergic receptors. Viklikaє mydriasis, paralysis of acomodation, movement of the internal pressure, tachycardia, xerostomia. Ignore the secretion of bronchial and ductal, sweat cavities. Relaxation of the smooth muscles of the bronchi, mucosal-intestinal tract, zhovchota sichovovidnoy systems - spasmolytic effect. Destroys (large doses) the central nervous system. After intravenous administration, the maximum effect is manifested after 2-4 minutes, after oral administration (in the form of droplets) after 30 minutes. In the blood, 18% binds with plasma proteins. Pass through the blood-brain barrier. Seen by nirkami (50% - in the same look).

Stopping speech Atropine

Virazkov's ailment of the duct of the duodenum, pylorospasm, cholelithiasis, cholecystitis, hostrial pancreatitis, hypersalivation (parkinsonism, poisoning with salts of important metals, with dental implants), irritable bowel syndrome, intestinal colic, and l oatrial block, proximal AV block, electrical activity of the ducts without pulse, asystole) for preoperative premedication; disruption by m-cholinergic stimulants and anticholinesterase LDs (reverse and irreversible diseases), incl. organophosphates; with radiological findings of the intestinal tract (if there is a need for a change in the tone of the intestinal tract), bronchial asthma, bronchitis with hyperproduction of mucus, bronchospasm, laryngospasm (prevention).

In ophthalmology. To expand the range of the reach of accommodative paralysis (definition of true refraction of the eye, maintenance of the fundus of the eye), the creation of functional calm in case of inflammatory diseases and injuries of the eye (iritis, iridocyclitis, choriosideitis, keratitis, thromboembolism and spasm central artery of the sitkivka).

Contraindication

Hypersensitivity, for ophthalmological forms - subcutaneous glaucoma (including with suspected glaucoma), subcutaneous glaucoma, keratoconus, childish glaucoma (1% of cases - up to 7 years).

Frozen until zastosuvannya

Illness of the cardiovascular system, with any increase in heart rate, may be unbearable: fleeting arrhythmia, tachycardia, chronic heart failure, IXC, mitral stenosis, arterial hypertension, acute bleeding; thyrotoxicosis (maybe worse tachycardia); increased body temperature (it is possible to move further away due to strangulation of the activity of sweat deposits); reflux esophagitis, herniation of the stravochid opening of the diaphragm, which is associated with reflux esophagitis (decreased motility of the stravochodal valve and the weakening of the lower stravochid sphincter can help improve the esophagus and gastroesophageal al relux); illness of the HKT, which is accompanied by obstruction: achalasia of the stravohod, stenosis of the hiatus (possible decrease in motility and tone, which can lead to obstruction and obstruction of evacuation in the place of the drain); intestinal atony in ailments of a frail age or weakened ailments (possible development of obstruction), paralytic intestinal obstruction (possible development of obstruction); illness with increased intraocular pressure: zakritokutova (mydriatic effect, which can lead to an increase in intraocular pressure, may lead to a hostile attack) and acute glaucoma (mydriatic effect may be secondary to deake nya vnutrishnyoochnogo vice, may need correction of therapy); nonspecific virazkovy colitis (high doses can aggravate intestinal motility, leading to remission of paralytic intestinal obstruction; in addition, it can manifest or worsen such a severe condition, like toxic megacolon); dryness in the mouth (trivale zastosuvannya may be more aggravated away from xerostomia); hepatic insufficiency (decreased metabolism) and nirk insufficiency (risk of development of side effects due to reduced excretion); chronic infection of the leg, especially in children of a young age and weakened ailments (changes in bronchial secretion can lead to a thickening of the secretion and elimination of plugs in the bronchi); myasthenia (stand can be affected by inhibition of diacetylcholine); hypertrophy of the anterior ridge without obstruction of the sieve passages, slashing of the sieve or scaling up to it, or illness, which is accompanied by obstruction of the sieve paths (including the neck of the sieve laceration due to hypertrophy ії premіhurovoї zoloza); preeclampsia (possible worsening of arterial hypertension); cerebral palsy in children, infantile cerebral palsy, Down's disease (reaction to anticholinergic LZ increases). For ophthalmological forms (dodatkovo) - age older than 40 years (nebezpeka manifest undiagnosed glaucoma), synechia of the iris membrane.

Congestion with vagity and breastfeeding

Side effects of speech Atropine

System effects

From the side of the nervous system and organs are sensitive: headache, confusion, sleeplessness, confusion of information, euphoria, hallucinations, mydriasis, paralysis of accommodation, impaired tactile sensation.

From the side of the cardiovascular system and blood (hematopoiesis, hemostasis): sinus tachycardia, exacerbation of myocardial ischemia through supramundane tachycardia, tympanic tachycardia and tympanic fibrillation.

From the side of the organs of the shlunkovo-intestinal tract: xerostomia, constipation.

Other: fever, atony of the intestines and sich mihur, zatrimka sichovipkannya, photophobia.

Mіstsevі efekti: minusche pokolyuvannya i p_dvischennya vnutr_shnyoochnogo vice; in case of trivial zastosuvanni - teasing, hyperemia of the hips; hyperemia and swelling of the conjunctivitis, development of the conjunctivitis, mydriasis and paralysis of accommodation.

When administered in single doses<0,5 мг возможна парадоксальная реакция, связанная с активацией парасимпатического отдела вегетативной нервной системы (брадикардия, замедление AV проводимости).

Interaction

Weaken the effect of m-cholinomimetics and anticholinesterase effects. LZ with anticholinergic activity potentiate atropine. With one-hour administration of antacids, which eliminate Al 3+ or Ca 2+ , the absorption of atropine from HCT changes. Diphenhydramine and promethazine are effective against atropine. Imoving the development of systemic side effects promotes tricyclic antidepressants, phenothiazines, amantadine, quinidine, antihistamines and other drugs with m-cholinoblocking powers. Nitrati zbіlshhuyt ymovіrnіst pіdvishchennya vnutrishnoochnogo vice. Atropine alters the absorption parameters of mexiletine and levodopa.

Ways to enter

Internally, in / in, in / m, PC, conjunctival, subconjunctival or parabulbarno path to electrophoresis. The ointment is placed behind the veki.

Zapobіzhnі come in speech Atropin

In patients with distal type AV block (with wide QRS complexes), atropine has little effect and is not recommended.

When instilling into the conjunctival sac, it is necessary to press the lower lacrimal point to avoid getting into the nasopharynx. In case of subconjunctival or parabulbar introduction of a change in tachycardia, Validol is indicated as an additional dose.

The iris is intensively pigmented to dilatation, and in order to achieve the effect, it is necessary to increase the concentration or the frequency of administration, which should be afraid of an overdose of the drugs.

Expansion of the eyes can provoke a hostile attack of glaucoma in especially older than 60 years and people with hypermetropia, slender to glaucoma in starvation, because the stench may sting the anterior chamber.

Eye drops Atropine - ophthalmological zasib, yogo zastosovuyut for diagnosis will become a patient's eye.

Components of a dewy journey that enters the warehouse, blows on the chin, provoking drug mydriasis.

In household minds, without the recognition of a doctor, the drug is blocked.

Installation instructions

In order to get it right, the pharmacist should present the doctor's prescription, which he knows.

Atropine (in droplets) - light-prosorium, non-staining, at a concentration of 1% in a 5 ml container (polyethylene capsule - dropper). Packing the medicinal product in a box of thin cardboard, when buying, turn it over, which is a report instruction from the packing. Drops of eyes of Atropin are allowed at the retail store for a prescription from the doctor.

Atropine is a substance based on the growth components of the alkaloid class, which is to avenge the growth from the paslon class.

The drug improves the circulation of the eyelids in the eye apple and provokes the expansion of the eyes, which leads to an increase in pressure, progression of the paralysis of accommodation, a decrease in the clarity of the eye, and a decrease in the shortness of the eyes.

When Atropine is recognized, it is littered with vehicles, read books and strain zir.

The maximum concentration of the drug in plasma is measured after thirty minutes after administration of the drug. Penetration of the lips through the conjunctiva of the eyes and causing an increase in the flow of the eyes, an increase in the intraocular pressure.

In patients with glaucoma types of glaucoma, the drug causes an increase in symptoms. Povnotsіnny zіr vіdnovlyuєє protyag chotirioh days after the completion of the jubilation of Atropin.

For lonely occasions, the renewal of the functions of the eye needs these days. After the completion of this term, the term is normal to react to subdivisions, to expand quickly and expand beyond reflexives.

Korisn_ power likіv

Ophthalmologists zastosuvannya Atropin to lead to the power of the drug to increase the value of the eye, which makes it easier to follow the patient's internal bottom. Vykoristovuetsya with the method of follow-up when making a diagnosis.

Components of ophthalmic eye drops can be used for atrophy of the eye and relief of spasm in case of eye injury and opia. Atropine, zavdyaki spasmolytic effect, safe calm in case of eye injuries and weakness to the formation of blood clots. Without vicissitude, the rozchinya is driven out more.

Negative characteristics of Atropine ingestion are indicated in patients with increased sensitivity to the drug components, with particular types of cataracts, glaucoma and in people with increased internal pressure.

A number of chronic illnesses (cardiac arrhythmia, systematic reduction of arterial pressure, depression of a hypertensive crisis, nirk or liver failure, thrombophlebitis, adhesions on the bronchial leg) are treated for signs of Atropine eye drops, to avoid provocation ї side effects.

An ophthalmologist writes down a note for the treatment of the eye, having read the medical record of a person with ill eyes. The patient with full responsibility must be informed of the doctor about health problems.

Showing that zastosuvannya at the sight of the difference

Assign droplets of the eyes of Atropine for the diagnosis and revision of the fundus of the eye, for the relief of spasm and pain in case of injuries of the eye. Fahіvtsem podbiraєtsya more precisely dozuvannya that concentration of likіv, after which you write a prescription, for the presentation of yoga in the pharmacy.

Even before the recognition of ophthalmic streaks, the patient has won lenses, then for an hour they are inspired and replaced with eyepieces. In the case of a bright sun, the vicorist should use sunscreen eyepieces with a shifting filter of ultraviolet changes.

In ophthalmology, eyedrops stagnate at the sight of water, burying in the eye, near the bone, like a medicine. Burying is carried out in a singing way, so that the medicine gets into the throat of the sick person.

Zavdyaks warehouse Atropin know zastosuvannya in a number of areas of medicine. Anesthesiologists should introduce one hour of surgery to reduce the severity of the sinuses, changes in reflex reactions.

In case of extended organs of the shlunkovo-intestinal tract for additional x-ray changes, Atropine is prescribed to reduce the activity and tension of these organs.

Ophthalmologists vykoristovuyut likarsky zasib when treating severe inflammation of the eyes (iritis, keratitis, iridocyclitis) and in trauma.

Try to expand, skilki di rozchin. Shvidke penetration of the drug, that the maximum concentration of active speech is observed in patients through the first year after the stagnation. Revival of the natural functions of the eye is coming for this day.

Contraindication before victoria

As a potent drug Atropine may be contraindicated:

keratocon;
glaucoma of closed-vugular form;
synechia of the iris membrane;
increased sensitivity of the eyes;
hypothermia;
increased body temperature;
mitral stenosis;
arrhythmias of the heart;
hypertension (systematic increase in arterial pressure);
vinification of the fetus;
a century older than sixteen years.

Under observation:

children from age to seven years;
grown up for forty years through the development of glaucoma.

Schob zastosovuvati Atropin, sled vrakhovuvat yogo sumsnіst іz likarskim zabomami. Beware of weakening of m-cholinomimetics and anticholinesterase in case of total intake. Antacids may be present in aluminum and calcium stores, and may interfere with the absorption of Atropine in the intestinal tract.

Antihistamines can reduce the risk of developing side effects in the form of congestion of ophthalmic drops. Appointment about the prescription of drugs to carry out the drug under suvorim control of the results.

Video

Side effects and consequences

Trivaliy course of taking the drug Atropine is indicated at the critical stage of the patient. Destroyed by the dawn, as if calling out the components of the difference, allows the person to be able to work loudly, for which the tension of the eyes is invisible to me.

From the physical exchanges, the problems are blamed on the deterioration of health - tse manifesting side reactions to the body on the drug.

In case of congestion of ophthalmic drops of Atropin, side effects are observed in the eyes:

nabryaku povіk ta con'junctivitis;
bumps of the eyeball;
hyperemia of the shkiri of the century;
midriase;
photo of that light-phobia;
growing vise in the middle of the eye.

Side effects of systemic nature:

migraine;
cardiac tachycardia;
zamorochennya;
dryness of the mucous membranes in the mouth;
upovіlnennya protsessіv in sich mihuri and shlunkovo-intestinal tract;
damage to the exhalation of feces.

When symptoms of a negative influx are detected, Atropine is given a prescription for drug treatment and is terminously converted to a doctor.

Likar skasovuє tsey zasib or prescribes for the continuation of the treatment an analogue of Atropin.

Vikoristannya drops Atropine sulfate 0.1, 0.5 and 1%

Introduce one or two drops of the drug atropine sulfate at a concentration of 1% trich into the eye at equal intervals of six years. The ophthalmologist shortens the intervals between diggings, so as to improve the standard of the organ of the eye. It is not possible to prescribe your own treatment with Atropine sulfate, the effects of the medication on health will be irreversible.

Subconjunctivally vicariously vaccinated 0.1% total in 0.2 to 0.5 ml. Parabulbarno vіd 03 to 05 ml.

In case of electrophoresis through the hands, for the additional face-to-face bath, the concentration of active speech is 0.5%.

Take the medicine at a temperature of five to six degrees in the refrigerator, or to a cold room up to sixteen to twenty degrees from the cold air. The term for saving the drug is three-fold depending on the date of selection.

Containers-droplets with a variety of curls, so that the hit will disappear again. Take the “dropper” out of the refrigerator and close it with a lid until four days later.

Yakshto zasіb did not get away with using the term specified in the instructions, such a drug is used for disposal. Vikoristovuvaty faces with the term of appurtenance, after passing - they are defended!

Indication for zastosuvannya for children

With special care and under the watchful eye of fakhivtsya, to carry out the jubilation of children with drops, with the reach of seven years, reaching the exact proportions of active speech.

In view of the severity of the loss of the eye, the doctor prescribes a course and dosing up to two doses of the amount of 0.5% up to three times for production, with intervals for six years. In children of the early age, drops of Atropine are used as a splendid method for trivalo therapy.

For diagnosing ailment of the eyes, medical doctors should be used from a non-trivial period of infusion. Іsnuyut preparations for zbіlshennya zіnitsі z rehabilitation in one day. The administration of medications in this group will be docilly for carrying out manipulations on the child's oral apparatus.

Administer the drug at the eye of the child, following the technique of effective instillation.

Faces are spent on the conjunctiva. Take care of Atropin at the empty nose and mouth.

The child is laid on a horizontal surface, and the head is turned at the side of the eye, where the burial will be carried out.

Squeeze the mucus canal with your finger (press without squeezing on the canal and squeeze it until the child is transferred), inject faces, let the medicine spread evenly on the surface, squeeze the canal. At the first entry, the child is under constant control of fahivtsya.

Atropine is available in the following forms:

Rozchin for injections in the form of 1 ml of 1 mg atropine sulfate (in ampoules of 1 ml);
Eye droplets 1% in 1 ml of 10 mg atropine sulfate (5 ml in polyethylene bottles).

Atropine is an anticholinergic and antispasmodic agent. Speech is also active - a brittle alkaloid, which is found in the leaves of those native plants of the solanaceous family, such as henbane, beladona, dope. The main chemical peculiarity of the drug is related to its ability to block the m-cholinergic system of the body, as well as to rotting in the heart meat, organs with smooth muscles, the central nervous system and secretory cavities.

Zastosuvannya Atropin priyaє izmenshennuyu sekretoriї ї ї ї ї zloz, razlalennyu tonus smooth'yazovykh organіv, zіnitsі expansion, pіdvіschenny vnutrishnyokochnogo twitch and paralysis akomodatsiі (zdatnostі oka zmenyuvaty fokushnіvіdstan). This quickening of the heart activity after the stagnation of the faces is explained by the gaudy ripple of the bulging nerve. After injecting the drug into the central nervous system, it causes visual stimulation of the dichal center, and at higher toxic doses, it can lead to mental agitation (sudomi, hallucinatory hallucinations).

Atropine is prescribed:

Virazkov's ailment of the slough and 12-colon intestine;
Spasms of the biliary ducts, smooth lingual organs of the intestinal tract, bronchial tubes;
Hypersalivation (parkinsonism, poisoning with salts of important metals, dental implants);
bradycardia;
hostile pancreatitis;
Kishkova and Nirkov Kolka;
Syndrome of the teased colon;
Bronchospasm;
Bronchitis due to hypersecretion;
AV block;
laryngospasm;
Destroyed by anticholinesterase speeches and m-cholinomimetics.

Also, Atropine is used during X-ray examinations of the mucosal-intestinal tract, for premedication before surgical operations and in ophthalmology (for expanding the range and reach of accommodative paralysis with the method of designating true refraction ї eye, follow-up of the fundus of the eye, exaltation of spasm of the central artery of the network, ker, iridocyclitis, embolism and some eye injuries).

Ingestion of Atropine is contraindicated in case of hypersensitivity to the components that enter the warehouse of the drug.

Rozchin for injections

As a fallow indication Atropin should be injected subcutaneously, internally or internally at a dose of 0.25-1 mg, the frequency of ingestion is 2 times a day.

For the purpose of bradycardia, it is necessary to administer intravenously 0.5-1 mg, if necessary, after 5 minutes of administration, the drug is repeated. Child dosing is determined by body mass - 0.01 mg / kg.

For premedication, Atropine is administered internally 45-60 times before anesthesia:

Dorosli - 04-06 mg;
Children - 0.01 mg / kg.

Eye drops

When Atropine is ingested in ophthalmology, 1-2 drops of 1% are buried in the eye, the frequency of congestion (depending on the indications) is up to 3 times per day with an interval of 5-6 years. In some cases, it is possible to introduce 0.1% difference:

Subconjunctival - 02-05 ml;
Parabulbarno - 0.3-0.5 ml.

For electrophoresis, inject 0.5% of atropine from the anode through the poky.

With systemic ingestion of Atropine, the following may develop:

Tachycardia;
Dryness in the mouth;
Difficulty in cutting;
Zamorochennya;
Constipation;
photophobia;
Midriaz;
Paralysis of accommodation;
Damage to tactile sprinyattya.

In case of stasis of Atropin, in case of lustful eye disease, in some cases, one can blame:

Swelling of the conjunctivitis and hyperemia of the internal apple and povik;
Hyperemia of the hips;
Dryness in the mouth;
photophobia;
Tachycardia.

Atropine should be used to protect against ailments of the cardiovascular system, if there is an increase in the frequency of heart rates.

Tachycardia;
Mild arrhythmia;
ischemic heart disease;
Chronic heart failure;
Arterial hypertension;
Mitral stenosis.

Also, Atropine should be used to protect against thyrotoxicosis, acute bleeding, reflux esophagitis, elevated body temperature, increased internal pressure, ailments of the mucosal-intestinal tract, which are accompanied by obstruction , gestosis, dry mouth, non-specific viral colitis. insufficiency, hypertrophy of the anterior sinus without obstruction of the sebaceous pathways, mastthenia, infantile cerebral palsy, cerebral palsy in children, Down's disease.

Follow an interval of at least 1 year between the intake of antacid preparations and Atropine.

In case of parabulbar or subconjunctival administration of the drug with a change in tachycardia, the sick person should be given a tablet of Validol under tongue.

In the period of rejoicing with Atropine, we should protect it when busy with potentially unsafe types of activity and when caring for motor transport.

Behind the mechanism there are analogues of Atropin є: Bellacehol, Apamid Plus, Cyclomed, Tropicamide, Hyoscyamine, Midriacil, Cycloptik, Midrimax, Becarbon.

The drug is allowed for a doctor's prescription. The term of attachment to Atropine at temperatures up to 25 ° C becomes:

Rozchin for injections - 5 years;
Eye drops - 3 rocks.

Respect! Information is hoped solely for understanding. This instruction is not guilty of victoriousness as a helper for self-exaltation. The need for recognition, the way that dose is prescribed to the drug is determined solely by the doctor.

chemical name: bis (1R, 3r, 5S)-3-8-methyl-8-azabicyclo octane sulfate monohydrate;

main physical and chemical authorities: prozora bezbarvna homeland;

stock: atropine sulfate - 0.001 g (in ampoules 1 ml);

additional speech: hydrochloric acid 0.1 M, water for injection.

Release form. Rozchin for injections ( injection- vporskuvannya, pіdshkіrne, vnutrishnyom'yazov, vnutrishnyovenne and іn. The introduction into the tissue (judgment) of the body of small quantities of rozchiniv (most importantly medicinal) 0.1%.

Spasmolytic and anticholinergic diseases.

Effekti atropin pov'yazanі z blockade ( Blockade- increase or interruption of the conduction of electrical impulses in either the conductive system of the heart or the myocardium) of M-cholinergic systems, as they lose sensitivity to acetylcholine-mediator ( Mediator- Speech, which causes the transfer of nerve endings to the working organ and from one nerve cell to the tongue), which vibrates in the area of sensitive endings of postganglionic parasympathetic nerves. Pharmacological effects of atropine may be protractile, which are to blame for the presence of M-cholinomimetics ( cholinomimetics- medical treatment with a different mechanism of action, which is directly related to the stimulation of cholinergic receptors). The drug may have a central cholinolytic effect, which manifests itself in changes in contraction and muscle tension in parkinsonism ( parkinsonism– neurological syndrome, maddening dysfunction of the exchange of adrenaline, norepinephrine, dopamine and their effects in subcutaneous nerve nodes (ganglia). It is characterized by a rhythmic m'ulcer tremor (three fingers, sometimes killing and other parts of the body), rigidity, changes in the volume and stiffness of the hand, hypokinesis), connection with powerful peripheral M-cholinolytic authority. Atropine improves breathlessness. At high doses, it stimulates the cerebral cortex and causes psychomotor arousal, hallucinations ( Hallucinations- tse rozladi priynyattya, at some objects chi manifestations appear there, de not really), judge. Peripheral M-cholinolytic effect on atropine manifests itself in extended lines, paralysis ( Paralysis- the loss of strength in case of prevalent m'yazovyh ruhi after a slow or pathological change in the nerve that innervates the m'yazi) accommodation ( Accommodation- Understand, close to the term "adaptation". For example, the accommodation of the eye is the attachment to a clear tower of objects that are found on different windows of the eye), the movement of the internal vice. Tsya deya is taken for 6-7 years. Atropine causes tachycardia ( Tachycardia- increased heart rate up to 100 and more strokes per whilin. Blame for physical and nerve strains, diseases of the cardiovascular and nervous systems, ailments of internal secretion and ing) for blockage of the flaccid nerve, relaxation of the smooth mucosa of the internal organs (bronchi, herbal tract, gallbladder) that sechovividnі ways and іn.) , especially in spastic camps; Ignore the secretory function of the follicle ( Zaliza- organs that vibrate and see specific speech, like taking part in various physiological functions and biochemical processes of the body. The cells of the internal secretion see the products of their own life - hormones in the blood lymph. Saliva of the outer secretion - on the surface of the body, mucous membranes of the outer middle (sweat, slough, milk slough)) (bronchial, slough, slough, sweat and others.); in the event of a miscarriage, causing anesthesia.

Pharmacokinetics. Atropine sulfate is readily resorbed into the bloodstream during the month of administration and rapidly distributed in the body, passing through the blood-brain and placental barriers. Seen from the cross section as in the unchangeable view, so in the view of metabolites. The next amount of the drug is indicated in breast milk.

The drug is administered intravenously, intraperitoneally at a dose of 0.25 - 0.5 - 1 mg (0.25 - 0.5 - 1 ml) 1-2 times a day. Sometimes subconjunctivally 0.2-0.5 mg (0.2-0.5 ml) or parabulbarly 0.3-0.5 mg (0.3-0.5 ml).
With introductory anesthesia ( anesthesia- a deep dream, which is called out piece by piece, with a second awareness and pain sensitivity. Stopping with the method of pain relief during operations) with the method of changing the risk of depression by the vagus ( Vagus- (nervus vagus), X pair of cranial nerves) heart rate and changes in the secretion of sinus and bronchial ulcers - 0.3 - 0.6 mg under the skin or internally for 30 - 60 minutes before anesthesia; in combination with morphine (10 mg morphine sulfate) - one year before anesthesia.
For grown-ups, a single dose is 2 mg, dobova - 3 mg; for children, the dose in the fall should be: up to 6 months - 0.02 mg, from 6 months up to 1 year - 0.05 mg, 2 years - 0.2 mg, 3 - 4 years - 0.25 mg, 5 - 6 years - 0.3 mg, 7-9 years - 0.4 mg, 10-14 years - 0.5 mg twice a day. When used against anticholinesterase drugs - 2 mg intradermal 20-30 minutes until redness and dryness of the skin, expansion of the line and the appearance of tachycardia, normalization of the breath. With mild and severe disorders, atropine can be administered for 2 days.

Dryness at the mouth, dryness of the skin, scarlet-like drooping, dysphagia ( Dysphagia- discord, whether it be phases of the act of forging, or unacceptable, that we become ill when passing through the stravochid), sprag, tachycardia, damage to the dawn, paralysis of accommodation, psychomotor arousal, sudomi, zatrimka sich ( Zatrimka Sich- the venims of the Sichostate system of systems were borne by the Riznimi, with the Yakik -Vonystoy, the abnice of Otkhov, the sichovypinutal canal of the Uzhnovyk system of the central nervous systems, the smallers of the Zakhvoryuvan, the cluser of the switchboy), the temperaturis.

critocutaneous glaucoma; vuzkiy kut mizh ryadzhoy shell and horn ( Rogivka- (cornea), the anterior opening of the part of the outer shell of the eye, one of the yogo luminous media); organic damage to the heart and vessels; hypertrophy of the anterior fold; sickness nirok; cachexia ( Cachexia- the extreme stage of the body's exhaustion, which is more characteristic of severe weight loss, severe weakness, a decrease in the activity of physiological processes, mental disorder); miastema gravis (with a hint of withdrawal, if atropine is prescribed for changing side effects of antimuscarinic and anticholinesterase drugs); Increased sensitivity to the drug.

Diya Atropin-Darnytsia can be strengthened with one-hour ingestion of other drugs with an antimuscarinic effect (amantadine, other antihistamine drugs. Antihistamines- Medicinal speeches that will help or change the effects, viklikanі histamine, tobto. effects of expansion of capillaries and increased penetration, shortening of smooth muscles thinly), preparations of groups of butyrophenones, phenothiazines, tricyclic antidepressants ( Antidepressants- soobi, how to improve mood, relieve anxiety and stress, increase mental activity. Zastosovuyutsya for likuvannya depression)). The suppression of peristalsis under the direction of Atropin-Darnytsya can cause changes in the intake of other medical problems.

Symptoms: with a slight overdose - dryness in the mouth, widening of the jaws, impaired accommodation ( Damaged accommodation- Damage to the process of changing the breaking force of the eye for attaching to the attachment of objects that are seen in different places), tachycardia, difficulty in the passage of the eyes, atony of the intestine, congestion.
In severe cases - widening of the jaw, increased internal pressure, dryness of the mucous membranes and skin, increased temperature, tucked section, tachycardia, head pain, confusion, hallucinations, total loss of orientation, p zke psychomotor arousal; can rozvinutisya sudomi zі vtratoyu svidomosti, lowering the arterial pressure, coma.

Likuvannya: administration of an antidote Antidotes- likarski zasobi, scho zastosovuyutsya for likuvannya otruen z neshkodzhennya wipe off that usunennya pathological damage, scho vyklikayutsya him; In case of psychomotor agitation - intravenous chlorpromazine (2 ml of 2.5% solution). For sudoma - barbiturates (5-10 ml of 2.5% solution of hexenal sodium intravenously or up to 10-15 ml of 2.5% solution of hexenal intravenously - 3-4 ml with breaks of 30 s). With a sharp manifestation of hyperthermia ( Hyperthermia- Overheating of the body. A person at a body temperature of over 41-42C may experience a heat stroke) - ice on the head, groin, throatiness. With tachycardia - enderal.
In case of obstruction of the section - catheterization. In case of manifestation of intoxication ( Intoxication- poisoning the body with toxic speeches) - forcing diuresis ( diuresis- the number of sections, visions for the singing hour. In humans, the average diuresis is 1200-1600 ml), blood lubrication. Intravenous administration of glucose is shown ( Glucose- grape zukor, a carbohydrate from the monosaccharide group. One of the key products of the exchange of speech, which provides living cells with energy) with ascorbic acid.

Zastosovuyut z berezhnistyu in ailments with severe injuries of the cardiovascular system. In case of subconjunctival and parabulbar administration for the prevention of tachycardia, the sick person should be given a tablet of Validol under the tongue at the same time as Atropin-Darnitsa. Guard. To recognize the protection of children and persons of a frail age, zastosovuvat in ailments with diarrhea ( diarrhea- sooner vision of rare deformities, due to faster passage through the intestines due to increased peristalsis, impaired water absorption in the colon, and vision of the intestinal wall of a significant amount of ignition secretion), with viral colitis (may expand the swelling of the colon from the hyper.

To protect, especially for children, to stop when the temperature of the naukolichny middle is elevated (rhysic hyperexia), with hyperthermia, camps, which are accompanied by tachycardia (thyrotoxicosis ( Thyrotoxicosis- Syndrome, madness due to excess thyroxine and triiodothyronine on the target tissue. Causes of thyrotoxicosis are rich; The most common cause is diffuse toxic goiter (Graves' disease). The clinical picture includes the development of hormones in various organs. Characteristic symptoms of activation of the sympathoadrenal system: tachycardia, tremor, thirstiness, anxiety. Qi symptoms are caused by beta-blockers), heart failure, surgical intervention on the heart), with myocardial infarction ( myocardial infarction- ischemic necrosis of the myocardium, resulting in sudden changes in blood flow in one of the 1st segments. At the heart of IM is a thrombus, which has rapidly expanded, molded like a tie with an atherosclerotic plaque rupture) (risk of worsening ischemia ( Ischemia- local anemia due to mechanical blockage of the arteries or due to bleeding) of the myocardium ( Myocardium- m'yazova tissue of the heart, to become the main part of yoga masi. Rhythmical coordination of the contraction of the myocardium of the slunot and the atrium are controlled by the conductive system of the heart)), in case of hypertension.

Diagnosis of atropine on the esophageal sphincter ( Sphincter(Greek sphinkter, like sphingo - I squeeze) - circular m'yaz, which sounds or clicks with a short sound (for example, mouth) or transitional (for example, sich mihur in sechivnik) otvir) can cause reflux to become stronger ( Reflux(in porіvn.-stolіttya lat. refluxus - svorotny perebіg) - transfer of rare empty organs (grass, sichovovividnyh and іn) to the virulent (antiphysiological) direct, for example, throwing shlunkovy vmіstu in stravokhіd with diaphragmatic mushrooms). Under the hour, the receptionist of Atropina-Darnytsya needs to be taken care of, as it will require control from the side of the organization of the day (driving cars, caring with mechanisms too).

Wash away that term of saving. Take care of the light of the world from the protected one, from the place that is inaccessible to children! The term of applicability - statements on packaging.

Wash the permits. For a prescription.

Package. 10 ampoules of 1 ml.

Virobnik. CJSC "Pharmaceutical firm "Darnytsya".

Miscellaneous. 02093, Ukraine, m. Kiev, st. Boryspilska, 13.

Website. www.darnitsa.ua

This material was presented in a free form on the basis of official instructions for medical treatment of the drug.

The drug Atropin reduces the tone of the internal mucous membranes of the bronchi, the shunt and the sieve mucus. Changes in the secretion of sinus, sweat and bronchial congestion are prescribed. It is necessary to know in which doses the faces are taken, and if the stench may have side effects on the body.

Headache for Atropin - blocking of M-cholinergic receptors. The drug is to change the secretion of the slough in case of bronchial ailments. Also, Atropin to increase the heart rate for a therapeutic effect. Faces can reduce the tone in the bronchi and empty stomach. If the patient has a flaccid nerve tone, then Atropine is even stronger. Faces are poured into the expansion of the eyes in the eyes. Tse vіdbuvaєtsya at the moment of relaxation of m'yazіv in the shell of the eye.

Doctors prescribe Atropine as a symptomatic therapy for such illnesses:

Virazka shlonk;
Problems with the twelve-fingered intestine;
hostile pancreatitis;
At the moment of pylorospasm;
For therapy of zhovchnokam'yanoy ailments;
Treatment for cholecystitis;
Violent spasms in the intestines;
Problems with sichway paths;
Severe attacks of bronchial asthma;
To improve the tone of the nerve under the hour of bradycardia;
To reduce the tone of the activity of organs under the hour of X-ray.

Also, the drug can be considered an injectable drug for the following purposes:

Before the introduction of anesthesia at the time of surgery;
To relieve bronchial spasms in surgical intervention;
To reduce the secretion of the burrow;
Understanding the reflex reaction;
It is prescribed as an antidote for overdose of cholinergic drugs.

For a skin condition, it is necessary to know the exact dosing frequency of the intake. Only a doctor can competently recognize the course of excellence and praise for the correctness of therapy.

In some ways, the choice of Atropin is unsafe for a healthy patient. Doctors pick up faces in such situations:

Strong allergy to any component in the warehouse;
Problems with the heart system;
Blame a flashy arrhythmia;
attack tachycardia;
Deficiency in a robotic heart;
Ischemic attacks;
Unsafe with mitral stenosis;
Not prescribed for severe stage of arterial hypertension;
How can a patient be bleeding;
Unsafe drug for thyrotoxicosis;
Not prescribed for hyperthermic syndrome;
How does the patient have problems with the tube;
Unsafe with glaucoma;
It is not prescribed for problems with nirkami and liver;
Like the patient has a part of the cut;
Unsafe with serious brain damage.

If you try to beat the drug in specific situations, it can cause harm to the body. Obov'yazkovo pass obstezhennya, so that Atropin is correctly beaten.

It is necessary to know with which drugs Atropine is insane or it can cause side effects. Axis for the latest list of words:

Vikoristannya together with MAO inhibitors to bring to a change in the rhythm of the heart;
Zastosuvannya Atropin z Khinidine inducing an increase in cholinolytic disease;
If you take the drug at once from tannin, then weaken the effect of both speeches;
Atropine reduces the analgesic effect of conventional opiates;
The drug changes the hour of drug use;
Parallel intake of Diphenhydramine potentiates the effect of Atropine;
Vykoristannya haloperidol lead to zbіlshennya vice in the middle of the eye;
Zastosuvannya at once from sertraline viklikaє feel like depression and depression;
With the help of penicillin, bring both faces to strength;
If you mix Atropin together with ketoconazole, it will change the blood circulation.

So the fahіvtsі saw low іnshih vzaєmodіy, on yakі it is necessary to show respect before the reception:

The drug Atapulgіt will change the exuberant effect of Atropin;
Faces will, with parallel administration, reduce the therapeutic effect of Pilocarpina;
When vikoristannі octadine change the effect of Atropin;
How to win the faces at once from sulfanamide methods, there may be a big problem with nirk and liver;
Parallel intake of potassium preparations to bring up to the level of the tube. It can also cause bleeding;
Diagnosis of the drug Atropine is possible when taking antidepressants, Amantadine and Fenotiazine;
Be-yakі іnshі lіkarskі zasobi will be more smoky and children after the reception of Atropin.

If a patient takes other preparations for therapy, he needs to correct the dosage or take a dose. Only the doctor is guilty of virishiti.

Doctors saw a low illness, for which Atropine is prescribed with great care. In this case, the doctor is guilty of controlling the patient's state and regulating the dosing. The axis is a list of the main ailments, with which the drug can be damaged:

Cerebral palsy in children;
Problems from sechoviprosy;
Down's illness;
With hernias in the grass zone;
Be it a stage of virazic colitis;
At the moment of megacolonies;
Preservation for dosing to patients in the frail;
At the start of the stage of illness, legenia;
For children with autonomic neuropathy.

Patients with such ailments are obligated to follow the camp of health after zastosuvannya Atropin and see the doctor.

Physicians do not allow Atropin to be victorious for female women, whatever the term. Also, do not stop the drug at the time of breastfeeding. Scientists have brought that toxic speech can be consumed through milk to a child. Tse prizvede to strong allergies and health complications.

Be aware that Atropine has side effects such as confusion and mild hallucinations. The very same varto utrimatisya in the caravannya by car until the end of therapy. Doctors to please patients also do not work with mechanisms, as they require a great concentration of respect.

Atropine can be administered by the intravenous, intravenous, and subcutaneous methods. To reduce heart rate and change in bronchial ulcers, doctors prescribe 0.5 mg of the drug in case of a visible subcutaneous injection. It is necessary to administer it a year before anesthesia with morphine at once.

In cases of severe cholinergic disorders, inject the drug at a dose of 2 mg internally. It is necessary to administer Atropine to the skin in the first place. Apply the insertion of the liqiv following the reddening of the shkiri, or in the event of a tachycardia attack. In case of a severe stage of illness, vicorate the preparation 1-2 times.

The maximum dose for grown-up people is 3 mg per doba. A single dose of 1 mg Atropine can be administered. For children, it is selected individually by a doctor. Vaughn lie down in the form of a vіku that vag of the baby, and also in the stage of illness. For the protection of the next zastosovuvat dosing for patients of the frail age.

If a person has side effects, the doctor is guilty of changing the dose of Atropine or changing the frequency of injections.

If you administer too much of the drug to the patient, it may lead to worsened health problems. The first signs of overdose appear in such symptoms:

Strongly visible nudoti, vomiting;
The patient's vice decreases;
Vinica tremor;
Lyudina vodchuvaє peresbudzhennya;
Judge strongly;
At night it’s difficult to sip;
Hallucinations may occur;
The patient becomes nervous and drastic;
Blame hyperthermia;
The process of gnosis in the nervous system;
Decreased activity in the dichal zone.

As soon as the patient sees such symptoms, he may once again take Atropine and turn to the hospital. Doctors are guilty of promptly promit the tube and introduce into the body of cholinergic drugs. With symptoms of hyperthermia, it is necessary to wipe the patient with water towels and use antipyretic preparations.

As if a person is aware of that fear, the doctor prescribes injections of thiopental. You can also take Physostigmine. In case of glaucoma, the patient is guilty of digging Pilocarpine in the eyeball. At this point, you can work with an injection of Prozerin 3 times a day. The patient may be out of the clinic only after all the unacceptable symptoms pass.

In the instructions from the zastosuvannya, you can add all the side effects of the drug. Sound aggravated blame in case of individual intolerance to the liquor, or dependent dose to the liquor.

De z'are?	Pobichna diya
The slug may have such side effects	Seeing dryness in the mouth; Strong spraga; Change the taste of the eyes to the reception of the hedgehog; Problems with motility in the intestines; Decreased tone in zhovchi; Blame dysphagia; Problems of sechoviprosy.
At the heart zone, you can start so folded	attack tachycardia; Strong arrhythmia; attack of ischemic disorder; The appearance of the patient becomes a chervonim; Seems like a rush of blood to the body.
In the nervous system, there are such side effects	attack a strong headache; The patient is confused in the head; Blame a little nervousness and fear; It is important for people to get hoarse at night.
Zir can start so complicated	The patient's eyes expand; Blame photophobia; attack paralysis of accommodation; There is a vice in the middle of the eyes; The clarity of the dawn falls swiftly.
The dichal system has such side effects.	Reduced bronchial tone; The phlegm becomes more viscous; It is important for the patient to cough.
There are such side effects on the screen:	Chervony visip on the body; Viniknenny kropiv'yanki; Manifest exfoliative dermatitis; Strong allergy to the warehouse of liquids.
Other side effects on the drug	The patient begins to sweat less; The shkira at the entrance becomes dry; Vinica dysarthria; Shkіra can be blackened through sensitivity to the warehouse.

If any side effects are detected, it is necessary to inject the drug. The doctor can determine the reason for such a reaction. It is possible, necessary to reduce the dosage or replace Atropine by a similar method.

Keep the drug only in the original packaging. It is important to trim the ampoules at a temperature of three times more than +25 degrees and at least +15 degrees. Do not put Atropin by the refrigerator at any time. It is important that the children could not get enough faces to take the middle. The term for the attachment of ampoules is three times more than 3 years from the moment of extraction. Robiti іn'єktsії, yakscho Atropin є prostrochenim.

Since the patient is blamed for side effects on Atropine, the drug may indicate similar signs for therapy. Axis list of main related drugs:

Spasmoveralgin;
Liki Perfillon;
The drug Neoefrodal;
Atropine sulfuric acid;
Faces of Atromed.

Skin from these preparations may have their own side effects and contraindications. That is why it is necessary to read the instructions to zastosuvannya in front of vikoristannyam and obov'yazkovo consult with the doctor.

At the same time, you can get Atropin from looking at the ampoules from any pharmacy. Acts of a pharmacist should be recognized by a doctor with accurate dosing. The average price of the drug is 70 to 90 rubles. For qiu vartist you can get 1 ampoule of 0.1-hundredth grade.

Before trying to win Atropin, it is necessary to get acquainted with the observations of patients. From them it is possible to learn about the subtlety and effectiveness of the drug:

Valentina, 42 years old. I recently had a serious vein operation. Nebezpeka believed in the fact that in me there was a sprinkling of rokiv nevpinnі bronchospasm. It could have made the surgery easier. However, the drug was injected with Atropine to reduce the tone in the bronchi and prevent attack. The operation was successful and the spasms were not blamed on him. The injection with the drug was just a supplement and saved me at the time of such a serious procedure;
Vladislav, 32 years old. I was prescribed an injection of Atropine to treat an advanced form of cholecystitis. The doctor robbed the internal language of injections at the doctor's office, to follow the signs in the body. The drug is not viklikav sladnennya chi side effects. Atropine and true dopomogaє for complex therapy. Variation of ampoules in pharmacies is available;
Marina, 27 years. When I was severely disturbed by cholinomimetic drugs, I drank to the medicinal level. As an antidote drug vikoristovuvav zasіb Atropin. I was robbed by skin injections of 30 quilin until the onset of unacceptable symptoms. After the injection, my skin became dry at the injection site. However, other side effects did not bother me. The drug is right to supplement for such a serious disorder and not allowing a deterioration in health.

Atropine is a highly effective drug that can be more beneficial. The main speech of the tsgogo likarskogo zasobu є strong otrutoyu. Yogo is seen from certain roslins - beladoni, dope, scopolis, bleck and others.

The active component of the drug is atropine sulfate, which can be classified as alkaloids. This speech is called a heterocyclic basis, as to avenge the nitrogenous group, as it reveals biological activity. Vono zdatne svoєridny rank spend living organisms.

With vicarious microdose of speech, expressions of a splendid effect are manifested. Basically, Atropine acts as an anticholinergic drug, which also works as an m-cholinergic receptor blocker.

Atropine is a functional drug. Yogo is dispensed in a number of medicinal forms:

tablets containing 0.5 mg of oral speech;
0.1 percent difference in ampoules for injections of 1 mg;
rozchin for reception inside;
1-droplets of eyes in polyethylene jars of 5 mg;
glasses 0.0016 g, 30 pieces per pack;
powder.

Atropine infuses the human body with a path of blocking receptors, which leads to the destruction of nerve impulses. Behind its mechanism of speech, the neurotransmitter acetylcholine is even guessed. It is so self-consciously connected with receptors according to the speed of nerve impulses. At tsomu є kіlka vidіv tsikh sensitive endings. Atropine building blocks less M-receptors.

The mechanism of action of the drug is affected by the fact that vin can be associated with sensitive endings of nerve cells to acetylcholine. As a result, the transmission of nerve impulses in the singing division of the body is blocked.

On this basis, the following effects are predicted for drug exposure:

relaxation of smooth m'yazіv. The galvanizing activity of the parasympathetic system leads to a positive influx on the bronchi (expansion), the grass system and the sieve mihur;
change in the secretion of sweat, mucus, and sloughs. Also, the activity of the main organs of the herbal system, bronchi, decreases;
guard mydriasis - expansion of the lines. Building atropine binds with cholinergic receptors in the iris of the eye. As a result, there is a tension in the radial muzzle, which provokes the expansion of the chin;
paralysis of accommodation develops. Diya Atropina is grounded on the relaxation of the ciliary m'yaz of the eye, which leads to the agglomeration of the crystal. Such an effect is the cause of the development of far-sightedness;
increase in heart rates. Tse v_dbuvaєtsya through blocking di parasympathetic nervous system on the sinoatrial vuzol;
posterіgaetsya positive injection on the atrioventricular conduction;
with the introduction of large doses of Atropine, the expansion of great vessels is observed. In the wake of that cloth, twist the redness. In the case of a small number of medical professionals, such an effect is not expected. Regardless of the price, binding with specific receptors is expected to produce a positive result after taking the drugs, which the judges will expand.

This medical treatment is mainly zastosovuetsya for symptomatic exaltation of the first negative states for the manifestation of such diseases or pathologies:

virazkova ailment (shlunka, 12-colon intestine);
irritable bowel syndrome;
liver or nirkov rings;
for the prevention of spasms of smooth intestinal mucosa, zocrema for an hour of conducting a radiological examination;
bronchial asthma;
bradycardia;

prophylaxis of arrhythmias during the first hour of anesthesia;
manifestation of the Morgani-Adams-Stokes symptom complex;
promoted the vibrancy of m'yaziv sich mihur, which provokes mimicry sichovipskannya in children that grown up;
spermatorrhoea;
presence of chronic bleeding;
zhovchnokam'yana twig (for loosening the duct for the introduction of zhovchі);
destruction by organophosphorus slabs;
laryngospasm.

In ophthalmology, Atropine is used to expand the range. Most of all, it is necessary to have a good diagnosis of the dawn, at the hour when it is necessary to determine the very bottom.

Also, the choice of this medical treatment is pre-existing for the presence of serious injuries, or in the treatment of certain illnesses - iritis, keratitis, iridocyclitis and others.

rozchin for living. The optimal dosage is 0.25-1 mg 1 to 3 times per doba. For doba, a person can live no more than 3 ml of Atropine;
pills. The main recommendation is 0.5-2 tablets 1-3 times per doba;
rozchin for injections. You can enter internally, pidshkirno or internally. The optimal dose is 0.25-1 mg 1-2 times a day. In times of symptomatic therapy, start with the minimum amount of the drug. After the introduction of the first dose, check the sprat of whilin. Although there is no positive action, all manipulations are repeated;
eye drops. Stop through the skin for 5-6 years, 1-2 drops. at a time;
eye ointment. Vykoristovuetsya 1-2 times a day.

When vikoristanni Atropin should be remembered that the drug should be taken to an increase in the short-livedness of the heart.

Therefore, yoga with great care is prescribed to people who suffer from such pathologies:

fleeting arrhythmias;
heart failure;
ischemic heart disease;
mitral stenosis;
arterial hypertension

Also, with great care, this medical condition is prescribed for thyrotoxicosis, cerebral palsy, with elevated body temperature, with nirk and liver failure for the manifestation of other serious illnesses.

With the total intake of Atropine with other drugs, there is a risk of strengthening yoga. These include a lot of antihistamines, tricyclic antidepressants, phenothiazines, butyrophenones, amantadine.

Also, remember that a decrease in intestinal peristalsis can lead to an increase in the intake of any other drugs that were administered orally.

Negative manifestations, after overdose of Atropin, are observed after 40-60 minutes after taking the drug. The most widespread symptoms of this will be:

dryness of all mucous membranes;
reduced sweating;
increase in the number of heart rates;
a development of nudity, to go to vomit;
tremor of kintsivok;
difficulty breathing;
blackening of the skins;
destruction of dawn;
appearing in court.

Hand tremor

Side effects from the reception of Atropin.

To the side effects, which can be blamed for the hour of treatment with Atropine, we can mention:

development of tachycardia;
appearance of dryness in the mouth;
zamorochennya;
the emergence of difficult times from sechovipkannyam;
constipation;
midriaz;
fear of light;
damage to the tactile sprinyattya;
accommodation paralysis;
swelling and hyperemia of the eyes.

It is necessary to take care of the temperature again in Denmark, so as not to exceed +25°С. In this case, all the power factors of the drug are saved for 3 years (for injections - 5 years).

Vartist Atropina in Russian pharmacies to become from 11 to 59 rubles.

When buying these drugs, pay attention to yoga analogues:

Cycloptic;
Midrimax;
Becarbon;
Belacehol;
Tropicamide;

Cyclomed;
Midriacil;
Hyoscyamine,
Apamid Plus.

Sergiy, 29 years. I can give you Atropin, the rocks are one of the best and inexpensive drugs in this group. I work in the daily diagnostic center, demi all the time I have been given a preparation for the follow-up of the intestines. For a few years, the patient did not have any side effects after I received it.

Valeria, 41 r_k. Torik, they showed my sechokam'yana ailment. I felt bad for myself, for I didn’t smell it. Dopomіg Atropin, which may be mittevo having sunk into the mustache of the unacceptable mind. You can say what zasіb vryatuvav me.

Olga, 39 years old. Because of this, I became more and more disturbed by the cultivation of the garden. It seemed to be late, it avenged organophosphorus from the floor. My life was ruined by those who injected Atropin in the medical clinic. Vіn dopomіg neutralize diyu otti and fringe її negative influx on the internal organs.